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Dae-Ro Ahn

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  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (생물화학)
  • 연락처02-958-6645
  • 출신전공생유기화학
  • 학위박사
  • 최종출신대학University of Bern
  • 이메일

연구분야

생명의료기술을 위한 핵산화학

Nucleic acid chemistry for innovative biomedical technology

대표연구실적

-  Ki-Cheol Han, Eun Gyeong Yang*, Dae-Ro Ahn* /A highly sensitive, multiplex immunoassay using gold nanoparticle-enhanced signal amplification/Chem. Commun. 2012, 48, 5895 ? 5897 -  Kim KR, Kim DR, Lee T, Yhee JY, Kim BS, Kwon IC, Dae-Ro Ahn*/Drug delivery by a self-assembled DNA tetrahedron for overcoming drug resistance in breast cancer cells/Chem. Commun. 2013, 49, 2010 ? 2012 -  Kim KR, Lee YD, Lee T, Kim BS, Kim S, Dae-Ro Ahn*/Sentinel lymph node imaging by a fluorescently labeled DNA tetrahedron/Biomaterials, 2013, in press

논문(최근 5년)

-  Highly sensitive detection of a bio-threat pathogen by gold nanoparticle-based oligonucleotide-linked immunosorbent assay[Biosensors and Bioelectronics,2015-02-15] -  Utilizing the bioorthogonal base-pairing system of L-DNA to design ideal DNA nanocarriers for enhanced delivery of nucleic acid cargos[Chemical Science,2014-04-01] -  A dual-responsive pH-sensor and its potential as a universal probe for assays of pH-changing enzymes[ ANALYST,2015-04-01] -  A microwell plate-based multiplex immunoassay for simultaneous quantitation of antibodies to infectious viruses[ ANALYST,2015-03-01] -  Discovery of a non-cationic cell penetrating peptide derived from membrane-interacting human proteins and its potential as a protein delivery carrier[SCIENTIFIC REPORTS,2015-06-01] -  Utilization of a pH-responsive DNA motif for beta-lactamase assays[ BULLETIN OF THE KOREAN CHEMICAL SOCIETY,2016-04-01] -  Overcoming doxorubicin resistance of cancer cells by Cas9-mediated gene disruption[SCIENTIFIC REPORTS,2016-03-01] -  Nano-formulation of a photosensitizer using a DNA tetrahedron and its potential for in vivo photodynamic therapy[BIOMATERIALS SCIENCE,2016-02-01] -  Biophysical and chemical handles to control the size of DNA nanoparticles produced by rolling circle amplification[BIOMATERIALS SCIENCE,2016-04-01] -  A fluorogenic substrate of beta-lactamases and its potential as a probe to detect the bacteria resistant to the third-generation oxyimino-cephalosporins[ BIOSENSORS & BIOELECTRONICS,2016-03-01] -  Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs[ JOURNAL OF CONTROLLED RELEASE,2016-12-01] -  An Immunoassay Utilizing DNA-Coated Cage Protein As a Signal Generator[ BULLETIN OF THE KOREAN CHEMICAL SOCIETY,2014-08-01] -  Fluorogenic nanoreactor assembly with boosted sensing kinetics for timely imaging of cellular hydrogen peroxide[ CHEMICAL COMMUNICATIONS,2016-01-01] -  NMR-based Fragment Screening of Inhibitors Against p300 CH1 and HIF-1 CTAD Interaction[ BULLETIN OF THE KOREAN CHEMICAL SOCIETY,2016-10-01] -  Modular delivery of CpG-incorporated lipid-DNA nanoparticles for spleen DC activation[ BIOMATERIALS,2017-01-01]

특허(최근 5년)

-  L-DNA 나노케이지 구조를 가지는 약물 전달체[2015-02-12] -  면역분석 기반의 항원 검출용 키트 및 항원 검출 방법[2015-02-25] -  변형 뉴클레오티드 및 이를 이용한 실시간 중합효소 반응[2014-11-14] -  조영제 조성물 및 이를 이용한 바이오 영상화 방법[2015-01-16] -  신규 세포투과성 펩타이드 및 이의 용도[2016-08-05] -  시료 내 약물-내성 박테리아 검출용 프로브 및 이의 용도[2018-02-08]