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정상훈 교수

Sang Hoon Jung

INFO

  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (생물화학)
  • 연락처033-650-3653
  • 출신전공천연물과학
  • 학위박사
  • 최종출신대학서울대학교
  • 이메일

연구분야

천연물로부터 생리활성물질 분리, 정제 및 구조동정. 안과질환 억제 천연물소재 생리활성 in vitro 및 in vivo 스크리닝

The isolation, purification and structure elucidation of biological active molecules from natural products. In vitro and in vivo biological screening for the development of eye-related inhibiting substances.

대표연구실적

-  Kim K., Kang S.W., Ahn H.R., Song Y., Yang S.J., Jung S.H.*./ The leaves of persimmon (Diospyros kaki Thunb.) ameliorate N-methyl-N-nitrosourea (MNU)-induced retinal degeneration in mice. / J. Agric. Food Chem. / 2015년 9월 -  Jang H., Choi Y.S., Ahn H.R., Lee C.Y.* Jung S.H.* / Effects of phenolic acid metabolites formed after coffee consumption on retinal degeneration in vivo. /Mol. Nutr. Food Res. / 2015년 10월 -  Jung S.H., Kim K., Sohn, S.W., Yang S. / Association of aqueous humor cytokines with the development of retinal ischemia and recurrent macular edema in retinal vein occlusion. / Invest. Ophthalmol. Vis. Sci. / 2014년 4월

저서(최근 5년)

-  Coffee: Emerging Beneficial Effects on Ocular Health[2016-04-01]

논문(최근 5년)

-  Secretome Profiling Reveals the Signaling Molecules of Apoptotic HCT116 Cells Induced by the Dietary Polyacetylene Gymnasterkoreayne B[Journal of agricultural and food chemistry,2014-03-01] -  Cytokine levels of the aqueous humour in central serous chorioretinopathy[Clinical and Experimental Optometry,2014-05-01] -  Baicalin Attenuates Laser-Induced Choroidal Neovascularization[Current eye research,2014-07-01] -  The extract of Chlorella vulgaris protects transformed retinal ganglion cells from oxidative stress-induced cells death[Journal of food biochemistry,2014-04-01] -  Association of aqueous humor cytokines with the development of retinal ischemia and recurrent macular edema in retinal vein occlusion[Investigative ophthalmology & visual science,2014-04-01] -  8-Hydrocalamenene, derived from Reynoutria elliptica, suppresses constitutive STAT3 activation, inhibiting proliferation and enhancing chemosensitization of human multiple myeloma cells[Journal of medicinal food,2014-03-01] -  Sulodexide inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy[BMB REPORTS,2014-11-01] -  Youngia denticulata attenuates diet-induced obesity-related metabolic dysfunctions by activating AMP-activated protein kinase and regulating lipid metabolism[Journal of Functional Foods,2015-10-01] -  Leaves of Persimmon (Diospyros kaki Thunb.) Ameliorate N-Methyl-N-nitrosourea (MNU)-Induced Retinal Degeneration in Mice[Journal of agricultural and food chemistry,2015-09-01] -  The effect of baicalin in a mouse model of retinopathy of prematurity[BMB REPORTS,2015-05-01] -  One-step isolation of sappanol and brazilin from Caesalpinia sappan and their effects on oxidative stress-induced retinal death[BMB REPORTS,2015-05-01] -  Effects of phenolic acid metabolites formed after coffee consumption on retinal degeneration in vivo[Molecular nutrition & food research,2015-10-01] -  Diospyros kaki Extract Inhibits Alkali Burn-Induced Corneal Neovascularization[Journal of medicinal food,2016-01-01] -  The leaves of Diospyros kaki exert beneficial effects on a benzalkonium chloride-induced murine dry eye model[Molecular vision [electronic resource],2016-04-01] -  A standardized extract of Rhynchosia volubilis Lour. exerts a protective effect on benzalkonium chloride-induced mouse dry eye[JOURNAL OF ETHNOPHARMACOLOGY,2018-04-01] -  Persimmon Leaves (Diospyros kaki) Extract Protects Optic Nerve Crush-Induced Retinal Degeneration[SCIENTIFIC REPORTS,2017-04-01] -  Phyllanthus emblica L. (Indian gooseberry) extracts protect against retinal degeneration in a mouse model of amyloid beta-induced Alzheimer's disease[JOURNAL OF FUNCTIONAL FOODS,2017-10-01] -  2,5-Dihydroxyacetophenone Induces Apoptosis of Multiple Myeloma Cells by Regulating the MAPK Activation Pathway[MOLECULES,2017-07-01] -  Development of an endoplasmic reticulum calcium sensor based on fluorescence resonance energy transfer[SENSORS AND ACTUATORS B-CHEMICAL,2017-08-01] -  Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model[PHYTOMEDICINE,2017-07-01]

특허(최근 5년)

-  감나무 추출물을 포함하는 망막질환 예방 또는 치료용 조성물[2014-07-29] -  생강나무속 식물 추출물을 포함하는 안압 하강용 조성물[2014-09-24] -  망막질환 예방 및 치료에 유용한 이고들빼기 추출물[2014-05-29] -  벌개미취 추출물 또는 이의 분획물을 포함하는 망막질환 예방 및 치료용 조성물[2014-04-25] -  이고들빼기 추출물, 이의 분획물 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 간 기능 개선용 약학적 조성물 및 간 기능 개선용 건강기능 식품조성물[2014-05-14] -  이고들빼기 추출물을 유효성분으로 함유하는 체중감량 및 비만의 예방과 치료용 조성물[2015-02-04] -  좁쌀풀 추출물을 포함하는 지방간 조성물[2016-12-30]