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최용수 교수

Choi, Yong Soo

INFO

  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (생물화학)
  • 연락처033-650-3505
  • 출신전공화학
  • 학위박사
  • 최종출신대학University of Illinois, Chicago
  • 이메일

연구분야

세포기반 또는 표적단백질 기반 천연물 활성탐색 및 천연물 구조동정

Cell or targeted protein based screening of natural products and structure identification of bioactive compounds

대표연구실적

-  Choi YS, Cho S, Lee C, Luu HM, Guo J/Contamination of ultrapure water with bisphenol A leached from polysulfone ultrafilter/Talanta/2012. 05.30 -  Choi Y, Jermihov K, Nam SJ, Maloney K, Qiu X, Main M, Chen SN, Mesecar AD, Pauli GF, Fenical W, Pezzuto JM, van Breemen RB/Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS/Analytical Chemistry/2011, 02.01 -  Choi YS and van Breemen RB/Development of a screening assay for ligands to the estrogen receptor based on magnetic microparticles and LC-MS/Combinatorial Chemistry and High Throughput Screening/2008.01

논문(최근 5년)

-  Efficient and Rapid Regioselective One-Pot Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from In Situ Generated Potassium Arylethynyltrifluoroborates through Sonogashira Reaction[European journal of organic chemistry,2013-10-01] -  Melittin suppresses EGF-induced cell motility and invasion by inhibiting PI3K/Akt/mTOR signaling pathway in breast cancer cells[Food and Chemical Toxicology,2014-06-01] -  Identification of eupatilin from Artemisia argyi as a selective PPARα agonist using affinity selection ultrafiltration LC-MS[Molecules,2015-07-28] -  Effects of phenolic acid metabolites formed after chlorogenic acid consumption on retinal degeneration in vivo[Molecular nutrition & Food Research,2015-07-14] -  Direct analysis of prostaglandin-E2 and -D2 produced in an inflammatory cell reaction and its application for activity screening and potency evaluation using turbulent flow chromatography liquid chromatography-high resolution mass spectrometry[ JOURNAL OF CHROMATOGRAPHY A,2016-09-09] -  Differences in the metabolic profiles and antioxidant activities of wild and cultivated black soybeans evlauted by corrrelation analysis[ FOOD RESEARCH INTERNATIONAL,2017-10-15] -  Eupatilin with PPARα agonistic effects inhibits TNFα-induced MMP signaling in HaCaT cells[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2017-11-04] -  AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A547 human lung cancer cells in vitro and in vivo[ JOURNAL OF ETHNOPHARMACOLOGY,2017-04-18] -  Metabolite profiling of peppers of various colors reveals relationships between tocopherol, carotenoid, and phytosterol content[Journal of food science : an official publication of the Institute of Food Technologists,2017-12-01] -  High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quarupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer celss[Biotechnology letters,2018-02-01] -  Association study between metabolomic profiling and bioactivity of crop diversity [한국분석과학회,2017-11-01] -  Eupatilin with PPAR alpha agonistic effects inhibits TNF alpha-induced MMP signaling in HaCaT cells[Biochemical and biophysical research communications,2017-11-01]

특허(최근 5년)

-  속수자 추출물을 함유하는 흉터개선용 조성물[2016-05-13] -  합성 라이브러리 및 천연물 스크리닝하는 방법 및 장치[2018-01-18] -  더덕 추출물을 함유하는 장 건강 개선용 조성물[2018-02-01] -  푸코잔틴을 포함하는 디하이드로테스토스테론 과다생성에 의해 유발되는 질병 예방 및 치료용 조성물[2018-01-09] -  LB 배지를 포함하는 미세조류 배양용 배지 조성물[2017-11-10]