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Yoosoo Yang

INFO

  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (생물화학)
  • 연락처029586655
  • 출신전공생명공학(생화학)
  • 학위박사
  • 최종출신대학성균관대학교 인문사회과학캠퍼스
  • 이메일

연구분야

막융합, 신경전달물질 방출, 스네어, 엑소좀

membrane fusion, neuroexocytosis, SNARE, exosome

대표연구실적

-  Bong-Kyu Choi*, Mal-Gi Choi*, Jae-Yeol Kim*, Yoosoo Yang, Ying Lai, Dae-Hyuk Kweon, Nam Ki Lee and Yeon-Kyun Shin/ Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking / Proc Nat Acad Sci USA / 201303 -  Yoosoo Yang et al., Dissection of SNARE-driven membrane fusion and neuroexocytosis by wedging small hydrophobic molecules into the SNARE zipper/ Proc Nat Acad Sci USA /201012 -  Han-Ki Lee*, Yoosoo Yang*, Zengliu Su*, Changbong Hyeon, Tae-Sun Lee, Hong-Won Lee, Dae-Hyuk Kweon, Yeon-Kyun Shin, and Tae-Young Yoon / Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1/Science/201005

논문(최근 5년)

-  Switch for the necroptotic permeation pore[Structure,2014-10-07] -  Beta-amyloid oligomers activate apoptotic BAK pore for cytochrome c release[Biophysical J,2014-10-07] -  SNARE zippering is hindered by polyphenols in the neuron[BBRC,2014-07-18] -  Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking[PNAS,2014-03-05] -  Polyphenols differentially inhibit degranulation of distinct subsets of vesicles in mast cells by specific interaction with granule-type-dependent SNARE complexes[Biochemical J,2014-03-15] -  Dissection of SNARE-driven membrane fusion and neuroexocytosis by wedging small hydrophobic molecules into the SNARE zipper[PNAS,2012-12-21] -  Dynamic light scattering analysis of SNARE-driven membrane fusion and the effects of SNARE-binding flavonoid[Biochemical and biophysical research communications,2015-10-01] -  Synaptotagmin-1 Is an Antagonist for Munc18-1 in SNARE Zippering[The Journal of biological chemistry,2015-04-01] -  Display of membrane proteins on the heterologous caveolae carved by caveolin-1 in the Escherichia coli cytoplasm[Enzyme and microbial technology,2015-11-01] -  A Chemical Controller of SNARE-Driven Membrane Fusion That Primes Vesicles for Ca(2+)-Triggered Millisecond Exocytosis[Journal of the American Chemical Society,2016-04-01] -  Inositol pyrophosphates inhibit synaptotagmin-dependent exocytosis.[Proceedings of the National Academy of Sciences of the United States of America,2016-07-01] -  Virus-mimetic fusogenic exosomes for direct delivery of integral membrane proteins to target cell membranes[ ADVANCED MATERIALS,2017-02-06] -  Exosome-SIRPa, a CD47 blockade increases cancer cell phagocytosis[ BIOMATERIALS,2017-01-03]

특허(최근 5년)

-  항알러지 물질을 스크리닝 하는 방법[2014-03-06] -  알러지성 질환의 치료 및 예방을 위한 펩타이드[2013-08-22] -  식물추출물을 포함하는 비만세포의 과립 분비 억제용 조성물[2013-08-28]