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마크 윈디쉬 교수

Marc Peter Windisch

INFO

  • 소속캠퍼스한국파스퇴르연구소
  • 전공 바이오-메디컬 융합
    (생물화학)
  • 연락처031-8018-8180
  • 출신전공분자바이러스학
  • 학위박사
  • 최종출신대학University of Heidelberg
  • 이메일

연구분야

분자 바이러스학

Molecular virology

대표연구실적

-  Dong-Kyun Ryu, Yeji Ahn, Wang-Shick Ryu, and Marc P. Windisch. “Development of a novel hepatitis B virus encapsidation detection assay by viral nucleocapsid-captured quantitative RT-PCR.” BioTechniques. 2015-11-02 [Epub ahead of print] -  Windisch MP, Jo S, Kim HY, Kim SH, Kim K, Kong S, Jeong H, Ahn S, No Z, Hwang JY. “Discovery of 2-iminobenzimidazoles as potent hepatitis C virus inhibitors with a novel mechanism of action”. Eur. J. Med. Chem. 2014-05-06 -  Kim HY, Li X, Jones CT, Rice CM, Garcia JM, Genovesio A, Hansen MA, Windisch MP. “Development of a multiplex phenotypic cell-based high throughput screening assay to identify novel hepatitis C virus antivirals”. Antiviral Res. 2013-05-06

논문(최근 5년)

-  Development of a novel hepatitis B virus encapsidation detection assay by viral nucleocapsid-captured quantitative RT-PCR.[BioTechniques,2015-11-02] -  Identification of a resveratrol tetramer as a potent hepatitis C virus helicase inhibitor.[Br J Pharmacol,2015-10-07] -  DDX60L Is an Interferon-Stimulated Gene Product Restricting Hepatitis C Virus Replication in Cell Culture.[J Virol,2015-10-15] -  The FDA approved drug irbesartan inhibits HBV-infection in HepG2 cells stably expressing sodium taurocholate co-transporting polypeptide.[Antiviral Therapy,2015-05-01] -  DDX3 DEAD-box RNA Helicase is a Host Factor that Restricts Hepatitis B Virus Replication at the Transcriptional Level.[J Virol,2014-09-17] -  Discovery of 2-iminobenzimidazoles as potent hepatitis C virus inhibitors with a novel mechanism of action[Eur. J. Med. Chem.,2014-05-06] -  Virtual Screening in Hepatitis B Virus Drug Discovery: Current State-of-the-Art and Future Perspectives.[CURRENT MEDICINAL CHEMISTRY,2018-02-21] -  Antiviral properties of chemiscal inhibitors of cellular anti-apoptotic Bcl-2 proteins.[VIRUSES-BASEL,2017-09-25] -  Characterization and structure-activity relationship study of iminodipyridinopyrimidines as novel hepatitis C virus inhibitor.[EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,2017-09-06] -  Abl Tyrosine Kinase Regulates Hepatitis C Virus Entry[FRONTIERS IN MICROBIOLOGY,2017-06-19] -  Virucidal activity of WHO-recommended formulations against enveloped viruses including Zika-, Ebola- and emerging Coronaviruses.[JOURNAL OF INFECTIOUS DISEASES,2017-03-15] -  A Novel Inhibitor IDPP Interferes with Entry and Egress of HCV by Targeting Glycoprotein E1 in a Genotype-Specific Manner[Scientific Reports,2017-03-23] -  GRIM-19 Restricts HCV Replication by Attenuating Intracellular Lipid Accumulation.[FRONTIERS IN MICROBIOLOGY,2017-04-11] -  TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus[Nucleic Acids Research,2017-01-09] -  Micrococcin P1, a naturally occurring macrocyclic peptide inhibiting hepatitis C virus entry in a pan-genotypic manner.[Antiviral Research,2016-08-01] -  Benzothiazepinecarboxamides: Novel hepatitis C virus inhibitors that interfere with viral entry and the generation of infectious virions[Antiviral Research,2016-02-02] -  Type I and type II interferon responses in two human liver cell lines (Huh-7 and HuH6)[Brazilian journal of anesthesiology (Elsevier),2015-12-28] -  In Silico Design and Experimental Validation of siRNAs Targeting Conserved Regions of Multiple Hepatitis C Virus Genotypes.[PLoS ONE,2017-07-21] -  Structure-Based Discovery of Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections[Journal of Medicinal Chemistry,2015-12-24]

특허(최근 5년)

-  Genome wide visual identification of human co-factors of HIV-1 infection[2014-12-30] -  Genome wide visual identification of human co-factors of HIV-1 infection[2014-04-09]

연구과제 수행 실적

B형 간염바이러스의 새로운 진입 억제물질 개발 감염병 미충족 의료 수요 대응 연구