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Kwon, Oh-Seung(Professor)

INFO

  • AffiliationKIST School
  • Majors Division of Bio-Medical Science & Technology
    (Biological Chemistry)
  • Contact Information02-958-5184
  • Major독성학(신경독성학)
  • DegreePh.D.
  • Highest Level of EducationUniversity of Arkansas
  • E-Mail

Field of Research

Toxicology, Toxicokinetics and Metabolism, Neuroimmunology, Doping Drug Analysis

Research Results

-  Mahbub Hasan, Ji-Eun Seo, -, -, - and O.S. Kwon*. Novel genes in brain tissues of EAE-induced normal and obese mice: Upregulation of metal ion-binding protein genes in obese-EAE mice. Neuroscience, 343, 322-336 (2017) (2017 February) -  Ji-Eun Seo, Mahbub Hasan, -, -, - and O.S. Kwon*. A leading role for NADPH oxidase in an in-vitro study of experimental autoimmune encephalomyelitis. Molecular Immunology, 72, 19-27 (2016 April) -  권오승, 칸다가다라, 임혜연, 강민정, 정병화, 정봉철, 하크마문: 다발성신경경화증의 치료 또는 예방용 조성물 및 이의 스크리닝 방법 (Screening of a new compound by using EAE mice model for the preventive treatment of multiple sclerosis). 관리번호 K05405, 출원번호 10-2010-0126263/등록번호 10-1324647, 등록일 2013.11.19

Treatise

-  Simultaneous analysis of 210 prohibited substances in human urine by ultrafast liquid chromatography/tandem mass spectrometry in doping control[Rapid communications in mass spectrometry : RCM,2015-02-01] -  Simultaneous ionization and analysis of 84 anabolic androgenic steroids in human urine using liquid chromatography-silver ion coordination ionspray/triple-quadrupole mass spectrometry[DRUG TESTING AND ANALYSIS ,2014-12-01] -  Activation of matrix metalloproteinase-9 (MMP-9) by neurotensin promotes cell invasion and migration through ERK pathway in gastric cancer[Tumor biology ,2015-08-01] -  Relationships between structure, inonization profile and sensitivity of exogenous anabolic steroids under elctrospary ionization and analysis in human urine using liquid chromatography-tandem mass spectrometry[ BIOMEDICAL CHROMATOGRAPHY,2015-08-01] -  Experimental autoimmune encephalomyelitis and age-related correlations of NADPH oxidase, MMP-9, and cell adhesion molecules: The increased disease severity and blood-brain barrier permeability in middle-aged mice[ JOURNAL OF NEUROIMMUNOLOGY,2015-08-01] -  Dependency of experimental autoimmune encephalomyelitis induction on MOG35-55 properties modulating matrix metalloproteinase-9 and interleukin-6[ NEUROCHEMICAL RESEARCH,2015-10-13] -  Sensitivity of GC-EI/MS, GC-EI/MS/MS, LC/ESI/MS/MS, Lg-Ag+CIS/MS/MS, and GC-ESI/MS/MS for analysis of anabolic steroids in doping control[DRUG TESTING AND ANALYSIS,2015-12-01] -  Relationship between chromatographic solution and amide structure of chiral 2-hydroxy acid as O-(-)-methoxycarbonlyated diastereomeric derivatives for enantiomeric separation on chiral gas chromatography[ JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,2016-01-10] -  Increased levels of brain serotonin correlated with MMP-9 activity and IL levels resulted in severe experimental autoimmune encephalomyelitis (EAE) in obese mice[ NEUROSCIENCE,2016-01-05] -  A leading role for NADPH oxidase in an in-vitro study of experimental autoimmune encephalomyelitis[ MOLECULAR IMMUNOLOGY,2016-05-01] -  Direct and rapid quantitation of ephedrines in human urine by paper spray ionization/high resolution mass spectrometry[Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,2016-08-01] -  Pharmacokinetic scaling of epirubicin using allometric and species-invariant time methods (J. Pharmaceutical Investigation, 45, 441-448, 2015 Mar)[Journal of Pharmaceutical Investigation,2015-03-01] -  Simple quantitation of formeterol and 11-nor-d9-tetrahydrocannabinol-9-carboxylic acid in human by liquid chromatography-tandem mass spectrometry in doping control (J. Chromatogr. B, 967, 8-12, 2014 Jul)[ JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,2014-07-03] -  LC-MS/MS methods for simultaneous analysis of growth hormone-releasing peptides and secretagogues in human urine (Mass Spectromerty Letters, 7)3), 55-63, 2016 Oct)[Mass Spectrometry Letters,2016-10-01] -  Novel genes in brain tissues of EAE-induced normal and obese mice: Upregulation of metal ion-binding protein genes in obese-EAE mice[NEUROSCIENCE,2017-02-01] -  Human chorionic gonadotropin (hCG) sub-chronic administration mediated MMP-9 activities and cytokine association deteoriate experimental autoimmune encephalomyelitis (EAE) condition in mice model[Journal of Pharmaceutical Investigation,2016-12-27] -  Analysis of glycerol with isolation of endogenous interferences using "Dilute and Shoot" strategy and high-resolution mass spectrometry in human urine for antidoping testing[Mass Spectrometry Letters,2016-12-31] -  Online Simultaneous Hydrogen/Deuterium Exchange of Multitarget Gas-Phase Molecules by Electrospray Ionization Mass Spectrometry Coupled with Gas Chromatography[Analytical chemistry ,2017-11-01] -  Development of a multi functional concurrent assay using weak cation exchnage solid phase extraction (WCX-SPE) and reconstitution with a diluted sample aliquot for anti doping analysis [Rapid Communications in Mass Spectrometry,2018-06-01] -  Methods for screening and confirming meldonium in human urine by high-resolution mass spectrometry and indentification of endogenous interferences for anti-doping testing[Mass Spectrometry Letters,2017-06-30]

Patent

-  뉴로텐신과 콜레시스토키닌을 사용한 위암 진단법[2014-09-01] -  은이온배위결합 이온분무/사증극자텐뎀질량분석기를 사용하는 동화작용 스테로이드 검출 방법[2015-09-01] -  생체 뇨 시료 중 에페드린류의 신속하고 정확한 직접 정량 분석방법[2016-06-20] -  뉴로텐신과 콜레시스토키닌을 사용한 위암진단법 (Composition of diagnostic biomaker for stomach cancer and method of diagnostic stomach cancer using the composition[2015-12-29] -  기체크로마토그래피-전기분무/질량분석기를 이용한 다환 방향족탄화수소의 이온화 및 검출방법[2015-07-23] -  생체 뇨 시료 중 에페드린류의 신속하고 정확한 직접 정량 분석방법[2016-06-20] -  기체크로마토그래피와 전기분무 이온화 장치의 연결 기술 및 이용법[2017-01-25] -  기체크로마토그래피-전기분무/질량분석기를 이용한 다환 방향족탄화수소 이온화 및 검출방법[2017-05-31]