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Oh Chang Hyun(Professor)

INFO

  • AffiliationKIST School
  • Majors Division of Bio-Medical Science & Technology
    (Biological Chemistry)
  • Contact Information02-958-5160
  • Major화학
  • DegreePh.D.
  • Highest Level of Education한양대학교
  • E-Mail

Field of Research

Medicinal Chemistry

Research Results

-   “FMS Kinase Inhibitors: Current Status and Future Prospects”. Med. Res. Rev. (IF=11.0) -  디플루오르페닐 유도체를 가지는 새로운 옥사졸리디논계 항생제 들과 그 제조방법 미국특허등롣

Treatise

-  A new series of diarylamides possessing quinoline nucleus: Synthesis, in vitro anticancer activities, and kinase inhibitory effect[European journal of medicinal chemistry,2014-11-01] -  Synthesis and Potent Anti-leukemic Activity of Novel 5'-Norcarbocyclic C-nucleoside Phosphonic Acids[Bulletin of the Korean Chemical Society,2014-12-01] -  Synthesis of Quinolinylaminopyrimidines and Quinazolinylmethylaminopyrimidines with Antiproliferative Activity against Melanoma Cell Line [Journal of enzyme inhibition and medicinal chemistry,2015-08-01] -  Design and synthesis of new RAF kinase-inhibiting antiproliferative[ EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,2017-02-01] -  Synthesis and in vitro antiproliferative and Antiinflammatory activity and Kinase Inhibitory effects Nea 1,3,4―triarylpyrazole derivatives [ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY,2017-02-01] -  A Progressive Review of V600E-B-RAF-Dependent Melano ma and Drugs Inhibiting It[MINI-REVIEWS IN MEDICINAL CHEMISTRY,2017-01-01] -  Design, synthesis, and in vitro antiproliferative and[ JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY,2016-12-01] -  Design, synthesis, broad-spectr um antiproliferative activity, and kinase inhibitory effect of triary lpyrazole derivatives possessing arylamides or arylureas moieties[ EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,2016-08-01] -  Broad-spectrum antiproliferative activity of a series of 6-(4-fluor ophenyl)-5-(2-substituted pyrimi din-4-yl)imidazo[2,1-b]thiazole derivatives[MEDICINAL CHEMISTRY RESEARCH,2016-05-01] -  A New Series of Cycloalkane- fused Coumarin Sulfonates: Synthesis and In Vitro Antiproliferative Screening[ BULLETIN OF THE KOREAN CHEMICAL SOCIETY,2016-02-01] -  Tricyclic coumarin sulphonate derivatives with alkaline phosphatase inhibitory effects: in vitro and docking studies[Journal of enzyme inhibition and medicinal chemistry,2018-01-01]

Patent

-  비정상 세포 성장 질환의 치료를 위한 단백질 키나아제 저해제인신규인다졸유도체,이의약학적으로 허용가능한 염 및 이를 유효성분으로 함유하는 약학적 조성물[2014-05-09] -  고 순도의 올메사탄 메독소밀(Olmesartan medoxomil)의 제조 및 정제방법[2014-07-07] -  흑색종 항증식 효과를 가지는 신규 이미다조옥사졸계 화합물 또는 이의제조방법[2016-07-28]