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Nho Chu Won(Professor)

INFO

  • AffiliationKIST School
  • Majors Division of Bio-Medical Science & Technology
    (Biological Chemistry)
  • Contact Information033-650-3651
  • Major영양독성학
  • DegreePh.D.
  • Highest Level of EducationUniversity of Illinois
  • E-Mail

Field of Research

Bioactivity of Natural Products

Research Results

-  Kyungsu Kang et al./A novel topoisomerase inhibitor, daurinol, suppresses growth of HCT116 cells with low hematological toxicity compared to etoposide/Neoplasia/2011 -  Kyung-Mi Lee/Nuclear factor-E2 (Nrf2) is regulated through the differential activation of ERK1/2 and PKC α/βII by Gymnasterkoreayne B/Cancer Letters/2013 -  노주원외 4명/A PHARMACEUTICAL COMPOSITION CONTAINING DAURINOL FOR THE PREVENTION AND TREATMENT OF CANCERS/8227512/2012

Treatise

-  Daurinol, a catalytic inhibitor of topoisomerase IIα, suppresses SNU-840 ovarian cancer cell proliferation through cell cycle arrest in S phase[International journal of oncology,2014-08-01] -  Phytoestrogenic activity of Aceriphyllum rossii and rapid identification of phytoestrogens by LC-NMR/MS and bioassay-guided isolation[European food research and technology = Zeitschrift für Lebensmittel-Untersuchung und -Forschung. A,2014-08-01] -  Secretome Profiling Reveals the Signaling Molecules of Apoptotic HCT116 Cells Induced by the Dietary Polyacetylene Gymnasterkoreayne B[Journal of agricultural and food chemistry,2014-03-01] -  Crepidiastrum denticulatum Extract Protects the Liver Against Chronic Alcohol-Induced Damage and Fat Accumulation in Rats[Journal of medicinal food,2014-04-01] -  Apigenin isolated from Daphne genkwa Siebold et Zucc. inhibits 3T3-L1 preadipocyte differentiation through a modulation of mitotic clonal expansion[Life sciences,2014-04-01] -  Bioavailability of Hydroxycinnamic Acids from Crepidiastrum denticulatum Using Simulated Digestion and Caco-2 Intestinal Cells[Journal of agricultural and food chemistry,2014-06-01] -  Gnetin H isolated from Paeonia anomala inhibits FcεRI-mediated mast cell signaling and degranulation[Journal of ethnopharmacology,2014-07-01] -  Effects of Surrounding Temperature on Antimicrobial Air Filters Coated with Sophora flavescens Nanoparticles[Aerosol science and technology,2014-03-01] -  Aceriphyllum rossii Extract and Its Active Compounds, Quercetin and Kaempferol Inhibit IgE-mediated Mast Cell Activation and Passive Cutaneous Anaphylaxis[Journal of agricultural and food chemistry,2014-04-01] -  Structural characterization of the pulmonary innate immune protein SPLUNC1 and identification oflipid ligands[The FASEB journal : official publication of the Federation of American Societies for Experimental Biology,2014-12-01] -  ErgosterolperoxidefromChagamushroom (Inonotus obliquus) exhibits anti-cancer activitybydown-regulationofthe β-catenin pathwayin colorectalcancer[Journal of ethnopharmacology,2015-09-01] -  Youngia denticulata attenuates diet-induced obesity-related metabolic dysfunctions by activating AMP-activated protein kinase and regulating lipid metabolism[Journal of Functional Foods,2015-10-01] -  Curcumin induces apoptotic cell death via Oct4 inhibition and GSK-3βactivation in NCCIT cells[Molecular nutrition & food research,2015-06-01] -  Youngiasides A and C Isolated from Youngia denticulatum Inhibit UVB-Induced MMP Expression and Promote Type I Procollagen Production via Repression of MAPK/AP-1/NF-κB and Activation of AMPK/Nrf2 in HaCaT Cells and Human Dermal Fibroblasts[Journal of agricultural and food chemistry,2015-06-01] -  Antimicrobial air filters using natural Euscaphis japonica nanoparticles[PLoS ONE ,2015-05-01] -  Chikusetsusaponin IVa methyl ester induces cell cycle arrest by the inhibition of nuclear translocation of b-catenin in HCT116 cells[Biochemical and biophysical research communications,2015-04-01] -  Gomisin J Inhibits Oleic Acid-Induced Hepatic Lipogenesis by Activation of the AMPK-Dependent Pathway and Inhibition of the Hepatokine Fetuin-A in HepG2 Cells[Journal of agricultural and food chemistry,2015-11-01] -  Effect of?Stellera chamaejasme?on cutaneous wound healing?in vitro and?in vivo[Fourth International Conference on Chemical Investigation and Utilization of Natural Resources,2016-07-01] -  Stellera chamaejasme and its isolated compounds induce cutaneous wound healing and anti-inflammatory activities[한국식품과학회,2016-08-01] -  Effects of light-emitting diode wavelengths on bioactive compounds in cabbage plants[한국식품과학회,2016-08-01] -  Inhibitory effect of the Larix sibirica and its various flavonoids on the IgE-stimulated mast cell activation and anaphylaxis[Fourth International Conference on Chemical Investigation and Utilization of Natural Resources,2016-07-01] -  The Stabilizing activity of Sphallerocarpus gracilis extracts and its isolated compounds on lgE-activated mast cells[Fourth International Conference on Chemical Investigation and Utilization of Natural Resources,2016-07-01] -  Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model[2016 International Symposium and Annual Meeting of The KSABC,2016-06-01] -  Daurinol, a cancer suppressing plant lignan with low hematological toxicity[2016년도 한국응용생명화학회 국제학술대회,2016-06-01] -  Effects of Hovenia dulcis Thunb. extract and methyl vanillate on atopic dermatitis­like skin lesions and TNF­α/IFN­γ­induced chemokines production in HaCaT cells[ JOURNAL OF PHARMACY AND PHARMACOLOGY,2016-08-01] -  Inhibitory effect of the branches of Hovenia dulcis Thunb. and its constituent pinosylvin on the activities of IgE-mediated mast cells and passive cutaneous anaphylaxis in mice[FOOD & FUNCTION,2015-03-01] -  Cassia tora Seed Extract and Its Active Compound Aurantio-obtusin Inhibit Allergic Responses in IgE-Mediated Mast Cells and[ JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2015-10-01] -  Inhibitory effect of the Larix sibirica and its various flavonoids on the IgE-stimulated mast cell activation and anaphylaxis[JOURNAL OF FUNCTIONAL FOODS,2016-12-01] -  Ligularia fischeri and its Constituents 3,4-Dicaffeoylquinic Acid Improves Obesity-induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism and Activating AMPK[JOURNAL OF FUNCTIONAL FOODS,2016-12-01] -  Disease-miRNAdb: a manually-curated database for the investigation of the microRNA-human disease relationship[Genes & genomics,2017-12-01]

Patent

-  무동력 태양광 추적기능이 구비된 집광형 태양광 발전장치[2014-06-20] -  간 보호용 조성물[2014-05-23] -  서시움 속 식물 추출물을 포함하는 항균용 조성물[2014-08-27] -  아임계 용매를 이용하는 대나무 잎 추출물의 추출방법[2014-07-17] -  천연항균입자와 탄소나노물질의 복합항균구조체 제조장치 및 방법[2014-08-26] -  망막질환 예방 및 치료에 유용한 이고들빼기 추출물[2014-05-29] -  벌개미취 추출물 또는 이의 분획물을 포함하는 망막질환 예방 및 치료용 조성물[2014-04-25] -  이고들빼기 추출물, 이의 분획물 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 간 기능 개선용 약학적 조성물 및 간 기능 개선용 건강기능 식품조성물[2014-05-14] -  돌단풍 추출물을 포함하는 항알러지용 조성물[2015-01-15] -  스타피레아 속 식물 추출물을 포함하는 항균용 조성물[2014-10-29] -  이고들빼기 추출물을 유효성분으로 함유하는 체중감량 및 비만의 예방과 치료용 조성물[2015-02-04] -  지구자 추출물을 포함하는 항알러지용 조성물[2015-07-01] -  자단향 추출물을 포함하는 피부 보습 및 항알러지용 조성물[2016-04-28] -  피뿌리풀 추출물을 포함하는 상처치료용 피부외용제 조성물[2016-02-19] -  식물 표현체 분석장치[2016-03-02] -  식물분석 자동화 시스템[2016-03-02] -  식물 상태 자동화 분석 장치 및 이를 이용한 식물 분석 방법[2015-10-26] -  신규한 다인다이올 화합물 및 이를 포함하는 항암 및 암예방용 조성물[2015-11-16] -  페오니아 아노말라 추출물을 포함하는 항알러지용 조성물[2015-11-17] -  바이오매스가 적은 물시료의 미생물 샘플링을 위한 여과장치 및 방법[2016-06-07] -  열화상 이미지를 이용한 작물의 엽온 계측 프로그램[2016-09-06] -  좁쌀풀 추출물을 포함하는 지방간 조성물[2016-12-28] -  물수세미 추출물을 포함하는 항균용 조성물[2016-12-26] -  피뿌리풀 추출물을 포함하는 상처치료용 피부외용제 조성물[2016-11-18] -  식물뿌리 표현형 측정을 위한 식물 생육 용기[2016-10-07] -  기린초 추출물을 유효성분으로 포함하는 항알러지용 및 피부 보습용 조성물[2017-02-02] -  유색감자를 포함하는 면의 제조방법[2016-06-02] -  누룩치 추출물을 포함하는 지방간의 치료용 조성물[2015-10-07] -  무산사상자 추출물을 포함하는 항알러지용 조성물[2017-09-11] -  이고들빼기 추출물을 유효성분으로 하는 허혈 재관류 손상의 예방 및 치료용 조성물[2017-09-07] -  휴대 단말기를 이용한 환경 정보 계측 시스템[2018-01-26] -  피뿌리풀 추출물 또는 그의 분획물을 포함하는 상처를 치료하기 위한 조성물 및 개체의 상처를 치료하는 방법[2017-11-10] -  피뿌리풀 추출물 또는 그의 분획물을 포함하는 상처를 치료하기 위한 조성물 및 개체의 상처를 치료하는 방법[2018-01-09] -  자외선 반사부를 이용한 양액 살균장치 및 방법[2017-12-18] -  플렉시블한 자외선 조사부를 이용한 양액 살균장치 및 방법[2017-11-27] -  기계학습을 이용한 작물의 생산량 예측장치 및 방법[2017-12-18] -  식물의 중량 및 함수량 산출 장치[2018-01-26] -  무산사상자 추출물을 포함하는 피부노화 개선용 조성물 [2017-12-06]