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Eun Mi Hwang(Professor)

INFO

  • AffiliationKIST School
  • Majors Division of Bio-Medical Science & Technology
    (Neuroscience)
  • Contact Information02-958-7216
  • Major신경과학
  • DegreePh.D.
  • Highest Level of Education아주대학교
  • E-Mail

Field of Research

Interactomics of ion channels

Research Results

-  Hwang EM, Kim E, Yarishkin O, Woo DH, Han KS, Park N, Bae Y, Woo J, Kim D, Park M, Lee CJ, Park JY. A disulphide-linked heterodimer of TWIK-1 and TREK-1 mediates passive conductance in astrocytes. Nat Commun. 2014;5:3227. 2014 Feb 5 -  Cho CH, Kim E, Lee YS, Yarishkin O, Yoo JC, Park JY, Hong SG, Hwang EM. Depletion of 14-3-3γ reduces the surface expression of Transient Receptor Potential Melastatin 4b (TRPM4b) channels and attenuates TRPM4b-mediated glutamate-induced neuronal cell death. Mol Brain. 7:52. 2014 Jul 22 -  Woo DH, Han KS, Shim JW, Yoon BE, Kim E, Bae JY, Oh SJ, Hwang EM, Marmorstein AD, Bae YC, Park JY, Lee CJ. TREK-1 and Best1 channels mediate fast and slow glutamate release in astrocytes upon GPCR activation. Cell. 151(1):25-40. 2012 Sep 28

Treatise

-  Optogenetic inactivation of the subthalamic nucleus improves forelimb akinesia in a rat model of Parkinson’s disease[Neurosurgery,2014-05-01] -  Extrasynaptic GABAA receptors in mediodorsal thalamic nucleus modulate fear extinction learning[Mol. Brain,2014-05-29] -  A Novel Cytosolic Isoform of Mitochondrial Trans-2-Enoyl-CoA Reductase Enhances Peroxisome Proliferator-Activated Receptor α Activity[Endocrinol Metab,2014-06-02] -  CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturation[Exp Mol Med,2014-07-11] -  Depletion of 14-3-3γ reduces the surface expression of Transient Receptor Potential Melastatin 4b (TRPM4b) Channels and attenuates TRPM4b-mediated glutamate-induced neuronal cell death[Mol Brain,2014-07-25] -  Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling[Nature Communications,2014-06-01] -  GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease[Nature medicine,2014-08-01] -  TWIK-1 contributes to the intrinsic excitability of dentate granule cells in mouse hippocampus[Mol Brain,2014-11-19] -  Physiological functions of the TRPM4 channels via protein interactions[BMB rep.,2015-01-15] -  Copine1 C2 domains have a critical calcium-independent role in the neuronal differentiation of hippocampal progenitor HiB5 cells[Biochemical and biophysical research communications,2014-10-01] -  The cytosolic splicing variant of NELL2 inhibits PKCb1 in glial cells[Biochemical and biophysical research communications,2014-10-01] -  Disinhibitory Action of Astrocytic GABA at the Perforant Path to Dentate Gyrus Granule Neuron Synapse Reverses to Inhibitory in Alzheimer's Disease Model[Experimental Neurobiology,2015-09-24] -  Suppression of 14-3-3γ-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells[Scientific Reports,2016-05-01] -  Surface expression of the Anoctamin-1 (ANO1) channel is suppressed by protein-protein interactions with β-COP[Biochemical and biophysical research communications,2016-06-01] -  Neuronal Expression and Cell-Type-Specific[Experimental Neurobiology,2016-06-30] -  Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.[ CHEMICAL BIOLOGY & DRUG DESIGN,2016-12-02] -  The Ca2+-activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons.[NATURE COMMUNICATIONS,2016-12-19] -  Optogenetic Inhibition of the Subthalamic[STEREOTACTIC AND FUNCTIONAL NEUROSURGERY,2016-03-11] -  Astrocytic Orosomucoid-2 Modulates Microglial Activation and Neuroinflammation[ JOURNAL OF NEUROSCIENCE,2017-03-15] -  Modulation of Endothelial BMPR2 Activity by VEGFR3 in Pulmonary Arterial Hypertension[ CIRCULATION,2017-03-29] -  Emerging Roles of TWIK-1 Heterodimerization in the Brain[International journal of molecular sciences,2018-01-01] -  Direct interaction with 14-3-3 gamma promotes surface expression of Best1 channel in astrocyte[Molecular Brain,2017-11-01] -  Expression of μ-Opioid Receptor in CA1 Hippocampal Astrocytes[EXPERIMENTAL NEUROBIOLOGY,2018-04-02] -  Expression of μ-Opioid Receptor in CA1 Hippocampal Astrocytes[EXPERIMENTAL NEUROBIOLOGY,2018-04-02] -  Expression of μ-Opioid Receptor in CA1 Hippocampal Astrocytes[EXPERIMENTAL NEUROBIOLOGY,2018-04-02]

Patent

-  성상교세포의 글루타메이트 방출 기작[2014-07-03] -  성상교세포의 글루타메이트 방출 기작[2014-10-28] -  페녹시프로판올 유도체 및 이를 함유하는 약학적 조성물[2014-12-18] -  망막의 ON/OFF 이극세포 선택적 유전자 발현 방법[2016-02-05]