본문 바로가기 대메뉴 바로가기
Chung, Hak Suk(Professor)

INFO

  • AffiliationKIST School
  • Majors Division of Bio-Medical Science & Technology
    (Biological Chemistry)
  • Contact Information02-958-6423
  • Major생화학 분자생물학 미생물학
  • DegreePh.D.
  • Highest Level of EducationHarvard University
  • E-Mail

Field of Research

Biochemistry/Chemical Biology/tmicrobiology

Research Results

-  Joo, S.H., Pemble, C.W. 4th, Yang, E.G., Raetz, C.R.H., Chung, H.S./Biochemical and Structural Insights into an Fe(II)/α-Ketoglutarate/O2-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO)./JMB/Oct 26 2018 -  Na, Y.R., Woo, D.J., Choo, H., Chung, H.S., Yang, E.G./Selective inhibition of the hypoxia-inducible factor prolyl hydroxylase PHD3 by Zn(ii)/Chem comm/Jul 7 2015 -   Chung, H.S., Raetz, C. R. H/Dioxygenases in Burkholderia ambifaria and Yersinia pestis that hydroxylate the outer Kdo unit of lipopolysaccharide /PNAS/JAN 11 2011

Treatise

-  Kdo hydroxylase is an inner core assembly enzyme in the Ko-containing lipopolysaccharide biosynthesis.[Biochemical and biophysical research communications,2014-09-26] -  Selective inhibition of the hypoxia-inducible factor prolyl hydroxylase PHD3 by Zn(ii).[Chemical communications,2015-05-21] -  The action of HIF-3α variants on HIF-2α-HIF-1β heterodimer formation is directly probed in live cells.[Experimental cell research,2015-08-15] -  ATP5B regulates mitochondrial fission and fusion in mammalian cells[ANIMAL CELLS AND SYSTEMS,2016-06-20] -  A facile method to prepare large quantities of active caspase-3 overexpressed by auto-induction in the C41(DE3) strain[ PROTEIN EXPRESSION AND PURIFICATION,2016-06-15] -  Crystal structure and activity of Francisella novicida UDP-N-acetylglucosamine acyltransferase[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2016-08-19] -  Poly-sgRNA/siRNA ribonucleoprotein nanoparticles for targeted gene disruption.[ JOURNAL OF CONTROLLED RELEASE,2017-03-28] -  Streptavidin-mirror DNA tetrahedron hybrid as a platform for intracellular and tumor delivery of enzymes.[JOURNAL OF CONTROLLED RELEASE,2018-06-28] -  Biochemical and Structural Insights into an Fe(II)/α-Ketoglutarate/O2-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO).[JOURNAL OF MOLECULAR BIOLOGY,2018-10-19] -  Caspase-4 disaggregates lipopolysaccharide micelles via LPS-CARD interaction.[SCIENTIFIC REPORTS,2019-01-29]

Patent

-  모노포스포릴 지질 A를 생산하는 세균, 및 이를 이용한 모노포스포릴 지질 A 생산 방법[2017-01-04] -  지질의 탈인산화용 조성물, 키트, 및 이를 이용한 탈인산화된 지질을 생산하는 방법[2017-03-06] -  헥사 아실화된 모노포스포릴 지질 A를 생산하는 세균, 및 이를 이용한 헥사 아실화된 모노포스포릴 지질 A 생산 방법[2017-07-19] -  피리치온-아연(Pyrithione-Zn)의 prolyl hydroxylase 3에 대한 선택적 저해 효과 와 그 용도[2018-05-02]