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황정환 교수

Jung Hwan Hwang

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처042-860-4633
  • 출신전공분자의학과
  • 학위박사
  • 최종출신대학충남대학교
  • 이메일

연구분야

대사질환, 폐혈증, 간질환, 염증성 장 질환, 마우스모델제작

Metabolic syndrome, liver disease, inflammatory bowel disease, generation of mouse model

대표연구실적

-  Hwang JH. et. al./Metformin ameliorates acetaminophen hepatotoxicity via Gadd45beta-dependent regulation of JNK signaling in mice/Journal of Hepatology/2015.07 -  Hwang JH. et al./The protective role of NAD(P)H:quinone oxidoreductase 1 on acetaminophen-induced liver injury is associated with prevention of adenosine triphosphate depletion and improvement of mitochondrial dysfunction/Arch Toxicol/2015.04 -  Gang GT. et al./Protection of NAD(P)H:quinoen oxidoreductase 1 against renal ischemia/reperfusion injury in mice/Free Radical Biology and Medicine/2014.02

논문(최근 5년)

-  In vivo imaging of islet transplantation using PLGA nanoparticles containing iron oxide and indocyanine green.[ MAGNETIC RESONANCE IN MEDICINE,2014-03-01] -  Inhibition of adenylyl cyclase type 5 prevents L-DOPA-induced dyskinesia in an animal model of Parkinson's disease[ JOURNAL OF NEUROSCIENCE,2014-08-27] -  Role of NADH:quinone oxidoreductase-1 in the tight junctions of colonic epithelial cells[BMB REPORTS,2014-09-01] -  Enhanced production of adenosine triphosphate by pharmacological activation of adenosine monophosphate-activated protein kinase ameliorates acetaminophen-induced liver injury[ MOLECULES AND CELLS,2015-01-01] -  NAD(P)H:Quinone oxidoreductase 1 activation reduces blood pressure through regulation of endothelial nitric oxide synthase acetylation in spontaneously hypertensive rats[ AMERICAN JOURNAL OF HYPERTENSION,2015-01-01] -  The indole derivative NecroX-7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation[ LIVER INTERNATIONAL,2015-04-01] -  The protective role of NAD(P)H:quinone oxidoreductase 1 on acetaminophen-induced liver injury is associated with prevention of adenosine triphosphate depletion and improvement of mitochondrial dysfunction[ ARCHIVES OF TOXICOLOGY,2015-04-01] -  Sulforaphane protects against acetaminophen-induced hepatotoxicity[ FOOD AND CHEMICAL TOXICOLOGY,2015-06-01] -  Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice[ JOURNAL OF HEPATOLOGY,2015-01-01] -  Anti-atherogenic effect of Humulus japonicus in apolipoprotein E-deficient mice[ INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE,2016-01-01] -  STEP signaling pathway mediates psychomotor stimulation and morphine withdrawal symptoms, but not for reward, analgesia and tolerance[ EXPERIMENTAL AND MOLECULAR MEDICINE,2016-02-26] -  Gadd45β ameliorates L-DOPA-induced dyskinesia in a Parkinson's disease mouse model[ NEUROBIOLOGY OF DISEASE,2016-03-01] -  Reply to Repurposing of metformin in liver injury: the JNK conundrum""[ JOURNAL OF HEPATOLOGY,2016-03-01] -  NQO1-knockout mice are highly sensitive to Clostridium difficile toxin A-induced enteritis[JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,2016-08-28]

특허(최근 5년)

-  환삼덩굴 추출물을 포함하는 간질환 또는 동맥경화의 예방 또는 치료용 조성물[2015-04-04] -  PspA를 유효성분으로 포함하는 퇴행성 뇌질환의 예방 또는 치료용 약학 조성물[2016-05-30]