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김승준 교수

Kim Seung Jun

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  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (단백체구조생물학)
  • 직급캠퍼스대표교수
  • 연락처042-860-4242
  • 출신전공생화학
  • 학위박사
  • 최종출신대학서울대학교
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연구분야

구조생물학, 생화학

structural biology, biochemistry

대표연구실적

-  41. Suk-Kyeong Jung, Dae Gwin Jeong, Sang J. Chung, Jae Hoon Kim, Byoung Chul Park, Nicholas K. Tonks, Seong Eon Ryu and Seung Jun Kim (2010) Crystal Structure of ED-Eya2; Insight into Dual Roles as a Protein Tyrosine Phosphatase and a Transcription Factor. FASEB Journal. 24:560-569. -  36. Navasona Krishnan, Dae Gwin Jeong, Suk-Kyeong Jung, Seong Eon Ryu, Andrew Xiao, C. David Allis, Seung Jun Kim* and Nicholas K. Tonks* (2009) Dephosphorylation of the C-terminal Tyrosyl Residue of the DNA Damage-Related Histone H2A.X is Mediated by the Protein Phosphatase Eyes Absent. Journal of Biological Chemistry. 284:16066-16070. -  57. Keum Ran Yu, Young Jun Kim, Suk-Kyeong Jung, Bonsu Ku, Hwangseo Park, Sa Yeon Cho, Hyeyun Jung, Sang J. Chung, Kwang Hee Bae, Sang Chul Lee, Bo Yeon Kim, Raymond L. Erikson, Seong Eon Ryu and Seung Jun Kim (2013) Structural Basis for the Dephosphorylating Activity of PTPRQ for Phosphatidyl Inositide Substrates. Acta Crystallographica. D69: 1522-1529.

논문(최근 5년)

-  Expression, purification, crystallization and preliminary crystallographic analysis of human myotubularin-related protein 3[ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY,2014-03-01] -  Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis[NATURE STRUCTURAL & MOLECULAR BIOLOGY,2014-06-29] -  Discovery of novel dusp4 inhibitors thgough the virtual screening with docking simulations[Bulletin of the Korean Chemical Society,2014-09-01] -  Structural analysis of the polo-box domain of human polo-like kinase2.[ PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS,2015-04-03] -  Virtual screening with docking simulations and biochemical evaluation of vhy phosphatase inhibitors[Chemical and Pharmaceutical Bulletin,2015-07-01] -  Identification of novel protein tyrosine phosphatase sigma inhibitors promoting neurite extension[ BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2015-11-20] -  structural study of the hd-ptp bro1 domain in a complex with the core region of stam2, alpha subunit of escrt-0[ PLOS ONE,2016-02-11] -  high-resolution crystal structure of the pdz1 domain of human protein tyrosine phosphatase PTP-bas[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2016-08-16] -  crystal structure of sp-ptp low-molecular weight protein tyrosine phosphatase from streptococcus pyogenes[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2016-08-19] -  structural insight into the critical role of the n-terminal region in the catalytic activity of dual-specificity phosphatase 26.[ PLOS ONE,2016-09-01] -  Discovery of novel striatal-enriched protein tyrosine phosphatase inhibtrs through structure-based virtual screening[Bulletin of the Korean Chemical Society,2016-10-12] -  The discovery of novel protein tyrosine phosphatase epsyilon inhibitors using a high-throughput screening approach.[Bulletin of the Korean Chemical Society,2017-01-09] -  two-track virtual screening approach to identify both competitive and allosteric inhibitors of human small c-terminal domain phosphatase 1[ JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN,2017-06-26] -  crystal structures of two forms of the acanthamoeba polyphaga mimivirus rab gtpase[ ARCHIVES OF VIROLOGY,2017-08-04]