본문 바로가기 대메뉴 바로가기
조이숙 교수

Cho, Yee Sook

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처042-860-4479
  • 출신전공의학과
  • 학위박사
  • 최종출신대학전북대학교
  • 이메일

연구분야

줄기세포, 리프로그래밍, 질환모델링

Stem Cell, Reprogramming, Disease modeling

대표연구실적

-  Son MY, Choi H, Han YM, Cho YS./Unveiling the critical role of REX1 in the regulation of human stem cell pluripotency./Stem Cells/in press -  Yoo CH, Na HJ, Lee DS, Heo SC, An Y, Cha J, Choi C, Kim JH, Park JC, Cho YS./Endothelial progenitor cells from human dental pulp-derived iPS cells as a therapeutic target for ischemic vascular diseases./Biomaterials/in press -  Lee J, Xia Y, Son MY, Jin G, Seol B, Kim MJ, Son MJ, Do M, Lee M, Kim D, Lee K, Cho YS./A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells./Angew Chem Int Ed Engl. 2012 Dec

논문(최근 5년)

-  Comparative receptor tyrosine kinase profiling identifies a novel role for AXL in human stem cell pluripotency[Hum Mol Genet,2014-04-04] -  Biomarker Discovery by Modeling Behcet's Disease with Patient-Specific Human Induced Pluripotent Stem Cells[ STEM CELLS AND DEVELOPMENT,2017-01-17] -  Pro-fibrotic effects of PFKFB4-mediated glycolytic reprogramming in fibrous dysplasia[ BIOMATERIALS,2016-11-01] -  Restoration of Mitochondrial NAD+ Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells[ STEM CELLS,2016-12-01] -  Generation and characterization of integration-free induced pluripotent stem cells from patients with autoimmune disease[ EXPERIMENTAL AND MOLECULAR MEDICINE,2016-05-13] -  A novel human model of neurodegenerative disease GM1 gangliosidosis using iPSCs demonstrates inflammasome activation[ JOURNAL OF PATHOLOGY,2015-09-01] -  Mitofusins deficiency elicits mitochondrial metabolic reprogramming to pluripotency[ CELL DEATH AND DIFFERENTIATION,2015-12-01] -  Proteomic and network analysis of proteins regulated by REX1 in human pluripotent stem cells.[PROTEOMICS,2015-07-01] -  Biochemical and molecular characterization of novel mutations in GLB1 and NEU1 in patient cells with lysosomal storage disorders[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2015-12-01]

특허(최근 5년)

-  미토푸신 억제제를 포함하는, 세포 리프로그래밍 촉진용 조성물 및 이의 용도[2016-08-03] -  Oct4 및 Sox2를 이용한 인간 치수강세포의 리프로그래밍 방법 및 이의 용도[2016-09-05] -  직접 리프로그래밍을 통한 유도 도파민성 전구세포 제조방법[2017-01-10] -  다능성 줄기세포의 제작, 유지, 증식을 증진하는 대사산물 및 이를 포함하는 조성물과 배양방법[2016-09-05] -  다능성 줄기세포의 제작, 유지, 증식을 증진하는 신규 저분자 화합물 및 이를 포함하는 조성물과 배양방법[2016-01-01]