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김선욱 교수

Sun-Uk Kim

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처043-240-6321
  • 출신전공분자생물학
  • 학위박사
  • 최종출신대학고려대학교 일반대학원
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연구분야

발생공학, 줄기세포생물학, 형질전환 질환모델 개발

Developmental Biotechnology, Stem Cell Biology, Transgenic Disease Model Generation

대표연구실적

-  Kim SU, Park YH, Kim JM, Sun HN, Song IS, Huang SM, Lee SH, Chae JI, Hong S, Sik Choi S, Choi SC, Lee TH, Kang SW, Rhee SG, Chang KT, Lee SH, Yu DY, Lee DS. Dominant role of peroxiredoxin/JNK axis in stemness regulation during neurogenesis from embryonic stem cells. Stem Cells. 2014 Apr;32(4):998-1011. -  Yoon SB, Choi SA, Sim BW, Kim JS, Mun SE, Jeong PS, Yang HJ, Lee Y, Park YH, Song BS, Kim YH, Jeong KJ, Huh JW, Lee SR, Kim SU, Chang KT. Developmental competence of bovine early embryos depends on the coupled response between oxidative and endoplasmic reticulum stress. Biol Reprod. 2014 May;90(5):104. -  Park YH, Kim SU, Lee BK, Kim HS, Song IS, Shin HJ, Han YH, Chang KT, Kim JM, Lee DS, Kim YH, Choi CM, Kim BY, Yu DY. Prx I suppresses K-ras-driven lung tumorigenesis by opposing redox-sensitive ERK/cyclin D1 pathway. Antioxid Redox Signal. 2013 Aug 10;19(5):482-96.

저서(최근 5년)

-  인류의가족, 인간의동반자 영장류[2015-03-31]

논문(최근 5년)

-  Differential expression pattern of gangliosides during the differentiation of human dental pulp-derived mesenchymal stem cells into dopaminergic neural-like cells[ANIMAL CELLS AND SYSTEMS,2014-06-01] -  16α,17α-epoxypregnenolone-20-oxime prevent LPS-induced NO production and iNOS expression in BV-2 microglial cells by inhibiting JNK phosphorylation[ BIOLOGICAL & PHARMACEUTICAL BULLETIN,2014-07-01] -  Developmental competence of bovine early embryos depends on the coupled response between oxidative and endoplasmic reticulum stress[BIOLOGY OF REPRODUCTION,2014-05-01] -  Insulin/IGF signaling-related gene expression in the brain of a sporadic Alzheimer's disease monkey model induced by intracerebroventricular injection of streptozotocin[JOURNAL OF ALZHEIMERS DISEASE,2014-06-01] -  Valproic acid enhances early development of bovine somatic cell nuclear transfer embryos by alleviating endoplasmic reticulum stress[ REPRODUCTION FERTILITY AND DEVELOPMENT,2014-03-01] -  Induction of autophagy during in vitro maturation improves the nuclear and cytoplasmic maturation of porcine oocytes [ REPRODUCTION FERTILITY AND DEVELOPMENT,2014-08-01] -  Dominant role of peroxiredoxin/JNK axis in stemness regulation during neurogenesis from embryonic stem cells[ STEM CELLS,2014-04-01] -  Relationship between ganglioside GD1a and inflammatory response in the coculture of human endothelial cells with porcine endothelial cells[ANIMAL CELLS AND SYSTEMS,2014-04-01] -  FOXM1-induced PRX3 regulates stemness and survival of colon cancer cells via maintenance of mitochondrial function[ GASTROENTEROLOGY,2015-10-01] -  Quantitative expression analysis of APP pathway and tau phosphorylation-related genes in the ICV STZ-induced non-human primate model of sporadic Alzheimer’s disease[ INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2015-02-01] -  Characterization of cerebral damage in a monkey model of Alzheimer’s disease induced by intracerebroventricular injection of streptozotocin[JOURNAL OF ALZHEIMERS DISEASE,2015-03-01] -  Mdivi-1, mitochondrial fission inhibitor, impairs developmental competence and mitochondrial function of embryos and cells in pigs[JOURNAL OF REPRODUCTION AND DEVELOPMENT,2015-04-01] -  Gain of a new exon by a lineage-specific Alu element-integration event in the BCS1L gene during primate evolution[ MOLECULES AND CELLS,2015-11-01] -  Exogenous gamma-tocotrienol promotes preimplantation development and improves the quality of porcine embryos[ REPRODUCTION FERTILITY AND DEVELOPMENT,2015-03-01] -  GRK5-knockout mice generated by TALEN-mediated gene targeting[ ANIMAL BIOTECHNOLOGY,2015-03-01] -  Anti-inflammatory actions of plant-derived multiple monoclonal antibody CO17-1A × BR55 related with anti-cancer effects in AOM/DSSinduced colorectal cancer mouse via downregulating of ERK1/2[ ANIMAL CELLS AND SYSTEMS,2016-09-01] -  Macaca specific exon creation event generates a novel ZKSCAN5 transcript[ GENE,2016-02-01] -  Mitochondria-targeted DsRed2 protein expression during the early stage of bovine somatic cell nuclear transfer embryo development[ IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL,2016-09-01] -  Identification of alternative variants and insertion of the novel polymorphic AluYl17 in TSEN54 gene during primate evolution[INTERNATIONAL JOURNAL OF GENOMICS,2016-12-01] -  Ganglioside GD1a promotes oocyte maturation, furthers preimplantation development, and increases blastocyst quality in pigs[JOURNAL OF REPRODUCTION AND DEVELOPMENT,2016-06-01] -  Peroxiredoxin II promotes hepatic tumorigenesis through cooperation with Ras/Forkhead box M1 signaling pathway[ ONCOGENE,2016-07-01] -  Inhibitory effect of imiquimod-induced psoriasis-like skin inflammation in mice by histamine H4 receptor agonist 4-methylhistamine[ SCANDINAVIAN JOURNAL OF IMMUNOLOGY,2016-06-01] -  Establishment and characterization of immortalized minipig neural stem cell line[ CELL TRANSPLANTATION,2017-02-01] -  Superovulatory responses in cynomolgus monkeys (Macaca fascicularis) depend on the interaction between donor status and superovulation method used[ JOURNAL OF REPRODUCTION AND DEVELOPMENT,2017-04-01] -  Alu-derived alternative splicing events specific to Macaca lineages in CTSF gene[MOLECULES AND CELLS,2017-02-01] -  Dual effect of fetal bovine serum on early development depends on stage-specific reactive oxygen species demands in pigs[PLOS ONE,2017-04-01]

특허(최근 5년)

-  변형 외막소포체를 포함하는 항감염성 면역증강용 조성물[2016-06-17] -  LPS가 결여된 아시네토박터 바우마니 유래 외막소포체를 포함하는 항암용 조성물[2016-06-17] -  디지토닌 처리된 정자를 이용한 정자매개형질전환 효율 증진 방법[2017-02-06] -  영장류 차량 이동용 케이지 장치[2015-11-27] -  스트렙토라이신 O의 처리에 의한 형질전환 동물의 생산성 향상 방법[2016-09-28]

연구과제 수행 실적

국가영장류센터사업 노인성 뇌질환 형질전환 동물모델 개발사업