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김선규 교수

Seon Kyu Kim

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (생명정보학)
  • 연락처042-879-8107
  • 출신전공의학
  • 학위박사
  • 최종출신대학충북대학교
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연구분야

생물정보학

Bioinformatics

대표연구실적

-  Kim SK, Roh YG, Park K, Kang TH, Kim WJ, Lee JS, Leem SH, Chu IS. Expression signature defined by FOXM1-CCNB1 activation predicts disease recurrence in non-muscle-invasive bladder cancer. Clin Cancer Res. 2014 Jun 15;20(12):3233-43. Epub 2014 Apr 8. -  Kim SK, Kim JH, Yun SJ, Kim WJ, Kim SY. APPEX: Analysis platform for identification of prognostic gene expression signature in cancer. Bioinformatics. 2014 Nov 15;30(22):3284-6. Epub 2014 Aug 4. -  Fukamachi H*, Kim SK*, Koh J, Lee HS, Sasaki Y, Yamashita K, Nishikawaji T, Shimada S, Akiyama Y, Byeon SJ, Bae DH, Okuno K, Nakagawa M, Tanioka T, Inokuchi M, Kawachi H, Tsuchiya K, Kojima K, Tokino T, Eishi Y, Kim YS, Kim WH, Yuasa Y, Tanaka S. A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors. J Exp Clin Cancer Res. 2019 Mar 12;38(1):127. *Equal contribution.

논문(최근 5년)

-  A Database of Gene Expression Profiles of Korean Cancer Genome.[Genomics Inform,2015-09-30] -  The c-MET Network as Novel Prognostic Marker for Predicting Bladder Cancer Patients with an Increased Risk of Developing Aggressive Disease.[Plos One,2015-07-30] -  Urinary MicroRNAs of Prostate Cancer: Virus-Encoded hsv1-miRH18 and hsv2-miR-H9-5p Could Be Valuable Diagnostic Markers.[Int Neurourol J.,2015-07-29] -  Next generation sequencing and urologic cancer.[Korean J Urol.,2015-02-01] -  A nineteen gene-based risk score classifier predicts prognosis of colorectal cancer patients.[Mol Oncol.,2014-12-01] -  APPEX: Analysis platform for identification of prognostic gene expression signature in cancer.[Bioinformatics,2014-11-15] -  Expression signature defined by FOXM1-CCNB1 activation predicts disease recurrence in non-muscle-invasive bladder cancer.[Clin Cancer Res.,2014-07-15] -  Activation of EZH2 and SUZ12 regulated by E2F1 predicts the diesease progression and aggressive characteristics of bladder cancer[CLINICAL CANCER RESEARCH,2015-08-12] -  Differential matrix metalloprotease (MMP) expression profiles found in aged gingiva[PLOS ONE,2016-07-08] -  Complex behavior of ALDH1A1 and IGFBP1 in liver metastasis from a colorectal cancer[PLOS ONE,2016-05-06] -  Feasibility of novel PPP1R15A and proposed ANXA11 single nucleotide polymorphisms as predictive markers for bevacizumab regimen in metastatic colorectal cancer[JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,2016-08-01] -  How do we manage high-grade T1 bladder cancer?: conservative or aggressive therapy?[Investigative and Clinical Urology,2016-07-01] -  Increased expression of herpes virus-encoded hsv1-miR-H18 and hsv2-miR-H9-5p in cancer-containing prostate tissue compared to that in benign prostate hyperplasia tissue[INTERNATIONAL NEUROUROLOGY JOURNAL,2016-06-01] -  Novel prognostic marker PRMT1 regulates cell growth via downregulation of CDKN1A in HCC[Oncotarget,2017-11-06] -  Transcriptomic features of primary prostate cancer and their prognostic relevance to castration-resistant prostate cancer[Oncotarget,2017-11-06] -  PSMB8 as a candidate marker of responsiveness to preoperative radiation therapy in rectal cancer patients[INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS,2017-08-01] -  Garlic extract in bladder cancer prevention: evidence from T24 bladder cancer cell xenograft model, tissue microarray, and gene network analysis[INTERNATIONAL JOURNAL OF ONCOLOGY,2017-07-01] -  Use of graph database for the integration of heterogeneous biological data[Genomics & Informatics,2017-03-01] -  Bioinformatic identification of prognostic signature defined by copy number alteration and expression of CCNE1 in non-muscle invasive bladder cancer[EXPERIMENTAL AND MOLECULAR MEDICINE,2017-01-13] -  Prediction of sarcopenia using a combination of multiple serum biomarkers[SCIENTIFIC REPORTS,2018-07-05] -  Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively[PLOS ONE,2018-08-27] -  How do we know that plants listen: advancements and limitations of transcriptomic profiling for the identification of sound-specific biomarkers in tomato[PLANT SIGNALING & BEHAVIOR,2018-11-17] -  Generation of whole-genome sequencing data for comparing primary and castration-resistant prostate cancer[Genomics & Informatics,2018-09-01] -  Beyond chemical triggers : evidence for sound-evoked physiological reactions in plants[FRONTIERS IN PLANT SCIENCE,2018-01-30] -  Whole genome MBD-seq and RRBS analyses reveal that hypermethylation of gastrointestinal hormone receptors is associated with gastric carcinogenesis[EXPERIMENTAL AND MOLECULAR MEDICINE,2018-12-03] -  Enhancer remodeling and microRNA alterations are associated with acquired resistance to ALK inhibitors[CANCER RESEARCH,2018-06-15] -  xploring the sound-modulated delay in tomato ripening through expression analysis of coding and non-coding RNAs[ANNALS OF BOTANY,2018-12-31] -  The anticancer effects of garlic extracts on bladder cancer compared to cisplatin: a common mechanism of action via centromere protein M[AMERICAN JOURNAL OF CHINESE MEDICINE,2018-01-01] -  c-MYC drives breast cancer metastasis to the brain, but promotes synthetic lethality with TRAIL[MOLECULAR CANCER RESEARCH,2019-02-01] -  The novel prognostic marker, EHMT2, is involved in cell proliferation via HSPD1 regulation in breast cancer[INTERNATIONAL JOURNAL OF ONCOLOGY,2019-01-01] -  SETDB1 regulates SMAD7 expression for breast cancer metastasis[BMB REPORTS,2019-02-01] -  Cks1 regulates human hepatocellular carcinoma cell progression through osteopontin expression[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2019-01-01]