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김용삼 교수

Kim, Yong-Sam

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (생체분자과학)
  • 연락처042-860-4156
  • 출신전공농화학과
  • 학위박사
  • 최종출신대학서울대학교
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연구분야

유전자교정기술, 당생물학, 바이오마커, 종양학

Genome editing technology, Glycobiology, Biomarker development, cancer biology

대표연구실적

-  Moon et al/Kim et al/Highly efficient genome editing by CRISPR-Cpf1 using CRISPR RNA with a uridinylate-rich 3'-overhang/Nature Communications/201809 -  Lee et al/Semi-quantitative measurement of a specific glycoform using a DNA-tagged antibody and lectin affinity chromatography for glyco-biomarker development/Molecular&Cellular Proteomics/01503 -  Kim et al/Functional proteomics study reveals that N-acetylglucosaminyltransferase V reinforces the invasive/metastatic potential of colon cancer through aberrant glycosylation on TIMP-1/Molecular&Cellular Proteomics/200801

논문(최근 5년)

-  Differential proteomic approach for identification and verification of aberrantly glycosylated proteins in adenocarcinoma lung cancer (ADLC) plasmas by lectin-capturing and targeted mass spectrometry[JOURNAL OF PROTEOMICS,2014-06-25] -  Semi-quantitative measurement of a specific glycoform using a DNA-tagged antibody and lectin affinity chromatography for glyco-biomarker development[ MOLECULAR & CELLULAR PROTEOMICS,2015-03-01] -  Direct regulation of E-cadherin by targeted histone methylation of TALE-SET fusion protein in cancer cells[ONCOTARGET,2015-09-15] -  Integrated GlycoProteome Analyzer (I-GPA) for automated identification and quantitation of site-specific N-glycosylation[SCIENTIFIC REPORTS,2016-02-17] -  Identification of mycobacterial antigens in human urine by use of immunoglobulin G isolated from sera of patients with active pulmonary tuberculosis[ JOURNAL OF CLINICAL MICROBIOLOGY,2016-06-01] -  Application of cancer-associated glycoforms and glycan-binding probes to an in vitro diagnostic multivariate index assay for precise diagnoses of cancer[ PROTEOMICS,2016-03-23] -  Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis[ NATURE CELL BIOLOGY,2016-05-01] -  Depletion of BIS sensitizes A549 cells to treatment with cisplatin[MOLECULAR & CELLULAR TOXICOLOGY,2016-03-01]

특허(최근 5년)

-  An identification method of glycoproteins using a specific lectin precipitation[2014-05-23] -  다중 당단백질의 발현량 및 당질변이의 측정을 통한 간암의 예측방법[2016-01-04] -  표적 유전자 특이적 핵산 프로브 및 FokI 제한효소 이량체를 이용하여 세포 내에서 표적 유전자를 특이적으로 편집하기 위한 조성물 및 이의 용도[2016-11-04]