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김정애 교수

Jung-Ae Kim

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처042-879-8129
  • 출신전공
  • 학위
  • 최종출신대학
  • 이메일

연구분야

후성유전학, 유전체학, 암생물학, 유전체 안정성, 크로마틴 조절

Epigenetics, Genomics, Cancer biology, Genome stability, Chromatin regulation

대표연구실적

-  Jeon J, McGinty RK, Muir TW, Kim JA, Kim J. /Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation/Nucleic Acids Research/2018-10-16 -  Cho JH, Yeom YI, Lee DC, Kim BK, Won M, Cho BC, Kang M, Park S, Yang SJ, Kim JS, Kim JA, Park KC/RNF25 promotes gefitinib resistance in EGFR mutant NSCLC cells by inducing NF-kB-mediated ERK reactivation/Cell Death and Disease/2018-5-22 -  Yang SJ, Park YS, Cho JH, Moon B, Ahn HJ, Lee JY, Xie Z, Wang Y, Pocalyko D, Lee DC, Sohn HA, Kang M, Kim JY, Kim E, Park KC, Kim JA, Yeom YI/Regulation of hypoxia response by flavin adenine dinucleotide-dependent modulation of HIF-1a protein stability/EMBO Journal/2017-04-13

논문(최근 5년)

-  Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation[NUCLEIC ACIDS RESEARCH,2018-10-16] -  RNF25 promotes gefitinib resistance in EGFR-mutant NSCLC cells by inducing NF-kB-mediated ERK reactivation[Cell Death and Disease,2018-05-22] -  Cooperative instruction of signaling and metabolic pathways on the epigenetic landscape[MOLECULES AND CELLS,2018-04-30] -  Metabolic signaling to epigenetic alterations in cancer[Biomolecules and Therapeutics,2018-01-01] -  Gut microbiome, a potent modulator of epigenetics in human diseases[Journal of Bacteriology and Virology,2017-06-01] -  Regulation of hypoxia response by flavin adenin-dependent modulation of HIF-1a protein stability[EMBO JOURNAL,2017-04-13] -  AKT-induced PKM2 phosphorylation signals for IGF-1-stimulated cancer cell growth[Oncotarget,2016-08-01] -  Pyruvate kinase isoenzyme M2 is a therapeutic target of gemcitabine-resistant pancreatic cancer cells[EXPERIMENTAL CELL RESEARCH,2015-08-01] -  Allosteric regulation of chromatin-modifying enzymes[BIOCHEMISTRY,2018-10-17]

특허(최근 5년)

-  메틸화-RACK1 단백질 검출 항체 및 그의 용도[2018-08-09]