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김석호 교수

Kim seok ho

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연구분야

ERK활성을 조절하여 면역회피 및 암 전이를 조절하는 API5 단백질의 기능 연구

Apoptosis inhibitor 5 (API5) regulates an immune escape and metastasis via ERK pathway

대표연구실적

-  seokho kim/ CD8 T cells regulate bone tumor burden independent of osteoclast resorption/ Cancer Research/ 2011 -  seokho kim/ CTHRC1 promotes pancreatic cancer progressing by regulating migration and adhesion of tumor cells/ Carcinogenesis/ 2013 -  API5 confers tumoral immune escape through FGF2-dependent cell survival pathway/ Cancer Research/ 2014

논문(최근 5년)

-  A PAUF-neutralizing antibody targets both carcinoma and endothelial cells to impede pancreatic tumor progression and metastasis[BBRC,2014-11-01] -  API5 confers tumoral immune escape through FGF2-dependent cell survival pathway.[Caner Res,2014-04-01] -  Apoptosis Inhibitor 5 Increases Metastasis via Erk-mediated MMP expression[BMB Rep,2014-09-01] -  Effect of exposure to interleukin-21 at various time points on human natural killer cell culture[Cytotherapy,2014-06-01] -  VP2 capsid domain of the H-1 parvovirus determines susceptibility of human cancer cells to H-1 viral infection[Cancer Gene Ther,2015-03-01] -  Natural Killer Cell Subsets and Receptor Expression in Peripheral Blood Mononuclear Cells of a Healthy Korean Population: Reference Range, Influence of Age and Sex, and Correlation between NK Cell Receptors and Cytotoxicity[ HUMAN IMMUNOLOGY,2017-02-01] -  Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSC) in pancreatic cancer[ONCOTARGET,2016-09-01] -  CTHRC1 promotes angiogenesis by recruiting Tie2-expressing monocytes to pancreatic tumors[ EXPERIMENTAL AND MOLECULAR MEDICINE,2016-09-01] -  Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-b-mediated MDSC infiltration[ONCOTARGET,2016-05-01] -  Pancreatic adenocarcinoma upregulated factor serves as adjuvant by activating dendritic cells through stimulation of TLR4 [ONCOTARGET,2015-09-01] -  Differential Matrix Metalloprotease (MMP) Expression Profiles Found in Aged Gingiva[PLOS ONE,2016-07-01] -  musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer[ ONCOGENE,2017-03-01] -  Irradiation of breast cancer cells enhances CXCL16 ligand expression and induces the migration og natural killer cells expressing the CXCR6 receptor[CYTOTHERAPY,2016-12-01] -  API5 confers cancer stem cell-like properties through the FGF2-NANOG axis[ONCOGENESIS,2017-01-02] -  Proteomic assessment of the relevant factors affecting prok meat quality associated with longissimus dorsi muscles in Duroc pigs[ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES,2016-11-01] -  Regional differences of proteins expressing in Adipose depots isolated from cows, steers and bulls as identified by a proteomic approach[ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES,2016-09-01] -  Age-associated chromatin relaxation is enhanced in Huntington's disease mice[AGING-US,2017-03-01] -  Age-associated chromatin relaxation is enhanced in Huntington's disease mice[AGING-US,2017-03-12] -  Aging-associated chromatin relaxation is enhanced in Huntington's disease mice[AGING-US,2017-03-12] -  Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breaset cancer[ ONCOGENE,2016-09-05] -  age-associated chromatin relaxation is enhanced in huntington's disease mice[AGING-US,2017-03-12] -  kahweol indeces apoptosis by suppressing BTF3 expression through the ERK signaling pathway in non-small cell lung cancer cells[ INTERNATIONAL JOURNAL OF ONCOLOGY,2016-12-14]

특허(최근 5년)

-  PAUF 단백질을 유효성분으로 포함하는 항원 제시 세포의 성숙화 유도용 조성물[2015-03-01] -  췌장암 치료용 융합 단백질 및 이의 용도[2017-04-25]