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이다용 교수

Da Yong Lee

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처042-860-4475
  • 출신전공
  • 학위
  • 최종출신대학
  • 이메일

연구분야

Neuroscience

신경과학

대표연구실적

-  Lee DY, Gianino SM, Gutmann DH. Innate neural stem cell heterogeneity determines the patterning of glioma formation in children.Cancer Cell 22: 131-138. 2012. -  Lee DY, Yeh TH, Emnett RJ, White CR, Gutmann DH. Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner. Genes Dev 24:2317-2329. 2010. -  Lee DY, Oh YJ, Jin BK. Thrombin-activated microglia contribute to death of dopaminergic neurons in rat mesencephalic cultures: Dual roles of mitogen-activated protein kinase signaling pathways. Glia 51:98-110. 2005.

논문(최근 5년)

-  The cytosolic splicing variant of NELL2 inhibits PKCβ1 in glial cells. [BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2014-10-29] -  Roles of mTOR Signaling in Brain Development.[EXPERIMENTAL NEUROBIOLOGY,2015-09-17] -  A novel human model of neurodegenerative disease GM1 gangliosidosis using iPSCs demonstrates inflammasome activation.[JOURNAL OF PATHOLOGY,2015-09-01] -  Mouse low-grade gliomas contain cancer stem cells with unique molecular and functional properties. [CELL REPORTS,2015-03-01] -  TWIK-1 contributes to the intrinsic excitability of dentate granule cells in mouse hippocampus. [MOLECULAR BRAIN,2014-11-19] -  GABA from reactive astrocytes impairs memory in mouse models of Alzheimer disease. [NATURE MEDICINE,2014-08-01] -  14-3-3-gamma regulates Copine1-mediated neuronal differentiation in HiB5 hippocampal progenitor cells.[EXPERIMENTAL CELL RESEARCH,2017-04-12] -  Schwann cell precursors from human pluripotent stem cells as a potential therapeutic target for myelin repair[STEM CELL REPORTS,2017-06-06] -  The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation.[Oncotarget,2017-07-18] -  Copine1 regulates neural stem cell functions during brain development.[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2018-01-01] -  A novel cytosolic isoform of mitochondrial trans-2-enoyl-CoA reductase enhances peroxisome proliferator-activated receptor alpha activity.[Endocrinology and Metabolism,2014-06-01]