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Yong-Hoon Kim(Professor)

INFO

  • AffiliationKRIBB School
  • Majors Bioscience
    (Functional Genomics)
  • Contact Information042-860-4683
  • Major수의형태학
  • DegreePh.D.
  • Highest Level of Education충남대학교
  • E-Mail

Field of Research

Studies on the regulation for hepatotoxicity by nuclear receptor

Research Results

-  Kim YH, Hwang JH, Kim KS, Noh JR, Choi DH, Kim DK, Tadi S, Yim YH, Choi HS, Lee CH/ Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice/ Journal of hepatology/ 2015.07.01 -  Kim DK, Kim YH, Jang HH, Park J, Kim JR, Koh M, Jeong WI, Koo SH, Park TS, Yun CH, Park SB, Chiang JY, Lee CH, Choi HS/ ERRγ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol/ Gut/ 2013.07.01 -  Kim YH, Hwang JH, Kim KS, Noh JR, Gang GT, Kim SW, Jang SP, Lee SJ, Her SH, Jeong KH, Kwak TH, Park WJ, Balyasnikova IV, Shong M, Lee CH/ NQO1 activation regulates angiotensin-converting enzyme shedding in spontaneously hypertensive rats/ Cardiovascular research/ 2013.09.01

Treatise

-  In vivo imaging of islet transplantation using PLGA nanoparticles containing iron oxide and indocyanine green[MAGNETIC RESONANCE IN MEDICINE,2014-03-02] -  Small heterodimer partner blocks cardiac hypertrophy by interfering with GATA6 signaling[CIRCULATION RESEARCH,2014-08-15] -  Inhibition of adenylyl cyclase type 5 prevents L-DOPA-induced dyskinesia in an animal model of Parkinson's disease[JOURNAL OF NEUROSCIENCE,2014-08-27] -  SIK2 is critical in the regulation of lipid homeostasis and adipogenesis in vivo.[ DIABETES,2014-11-01] -  PKB/Akt phosphorylation of ERRγ contributes to insulin-mediated inhibition of hepatic gluconeogenesis[ DIABETOLOGIA,2014-12-01] -  NAD(P)H:Quinone oxidoreductase 1 activation reduces blood pressure through regulation of endothelial nitric oxide synthase acetylation in spontaneously [ AMERICAN JOURNAL OF HYPERTENSION,2015-01-01] -  Sulforaphane protects against acetaminophen-induced hepatotoxicity[ FOOD AND CHEMICAL TOXICOLOGY,2015-06-01] -  Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice[ JOURNAL OF HEPATOLOGY,2015-07-01] -  Enhanced production of adenosine triphosphate by pharmacological activation of adenosine monophosphate-activated protein kinase ameliorates acetaminophen-induced liver injury[ MOLECULES AND CELLS,2015-10-01] -  The protective role of NAD(P)H:quinone oxidoreductase 1 on acetaminophen-induced liver injury is associated with prevention of adenosine triphosphate depletion [ ARCHIVES OF TOXICOLOGY,2015-11-01] -  STEP signaling pathway mediates psychomotor stimulation and morphine withdrawal symptoms, but not for reward, analgesia and tolerance[ EXPERIMENTAL AND MOLECULAR MEDICINE,2016-02-26] -  Gadd45β ameliorates L-DOPA-induced dyskinesia in a Parkinson's disease mouse model[ NEUROBIOLOGY OF DISEASE,2016-03-01] -  Reply to Repurposing of metformin in liver injury: the JNK conundrum[ JOURNAL OF HEPATOLOGY,2016-03-01] -  The orphan nuclear receptor ERRγ regulates hepatic CB1 receptor-mediated fibroblast growth factor 21 gene expression[PLOS ONE,2016-07-25] -  Orphan nuclear receptor SHP regulates iron metabolism through inhibition of BMP6-mediated hepcidin expression[SCIENTIFIC REPORTS,2016-09-01] -  Glucose-6-phosphate dehydrogenase deficiency improves insulin resistance with reduced adipose tissue inflammation in obesity[ DIABETES,2016-09-01] -  Anti-atherogenic effect of Humulus japonicus in apolipoprotein E-deficient mice[ INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE,2016-10-01] -  O-GlcNAcylation of orphan nuclear receptor estrogen-related receptor γ promotes hepatic gluconeogenesis[ DIABETES,2016-10-01]

Patent

-  환삼덩굴 추출물을 포함하는 간질환 또는 동맥경화의 예방 또는 치료용 조성물[2015-04-24] -  PsPA를 유효성분으로 포함하는 퇴행성 뇌질환의 예방 또는 치료용 약학 조성물[2016-05-30]