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Choi, Inpyo(Professor)

INFO

  • AffiliationKRIBB School
  • Majors Bioscience
    (Functional Genomics)
  • Contact Information042-860-4223
  • Major생물학
  • DegreePh.D.
  • Highest Level of EducationUniversity of Alabama
  • E-Mail

Field of Research

Cell therapy, stem cell function, immunology

Research Results

-  VDUP1 is required for the development of natural killer cells.Immunity. 2005 22(2):195-208. -  TXNIP maintains the hematopoietic cell pool by switching the function of p53 under oxidative stress.Cell Metab. 2013 Jul 2;18(1):75-85. -  Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity. Nature Communications 2016 7:13674

Treatise

-  MicroRNA-150 regulates the cytotoxicity of natural killers by targeting perforin-1[J Allergy Clin Immunol,2014-03-31] -  Thioredoxin-interacting protein hematopoietic stem cells and hematopoiesis[Curr Opinion Hematol,2014-07-01] -  Donor-derived natural killer cells infused after human leukocyte antigen-haploidentical hematopoietic cell transplantation: a dose-escalation study.[Biol Blood Marrow Transplant,2014-05-01] -  Integrated mRNA-MicroRNA Profiling of Human NK Cell Differentiation Identifies MiR-583 as a Negative Regulator of IL2Rγ Expression.[PLOS ONE,2014-10-15] -  Donor-Derived Natural Killer Cell Infusion after Human[ BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION,2016-02-01] -  Thioredoxin-interacting Protein Regulates Haematopoietic Stem Cell Ageing and Rejuvenation by Inhibiting p38 Kinase Activity[NATURE COMMUNICATIONS,2016-12-01] -  Suppressor of Cytokine Signaling 2 Negatively Regulates NK Cell Differentiation by Inhibiting JAK2 Activity[SCIENTIFIC REPORTS,2017-04-06] -  MicroRNA-150 modulates intracelluar Ca levles in naive CD8 T cells by tgargeting TMEM20[SCIENTIFIC REPORTS,2017-06-01] -  MicroRNA-150 modulates intracelluar Ca levels in naive CD8 T cells by targeting TMEM20[SCIENTIFIC REPORTS,2017-06-01] -  MicroRNA-150 moculates intracelluar Ca levels in naive CD8 T cells[SCIENTIFIC REPORTS,2017-06-01] -  MicroRNA-150 modulates intracellular Ca in naive CD8 T cells[SCIENTIFIC REPORTS,2017-06-01] -  MicroRNA-150 modulates intracelluar Ca levels in naive CD8 T cells[SCIENTIFIC REPORTS,2017-06-01] -  MicroRNA-150 modulates intracelluat Ca levels[SCIENTIFIC REPORTS,2017-06-01] -  Macrophage migration inhibitory factor interacts with thioredoxin-interacting protein and induces NF-κB activity[ CELLULAR SIGNALLING,2017-06-01] -  Understanding of molecular mechanisms in natural killer cell therapy.[ EXPERIMENTAL AND MOLECULAR MEDICINE,2015-02-13] -  Combining vasculature disrupting agent and Toll-like receptor 7/8 agonist for cancer therapy.[ONCOTARGET,2017-01-17] -  Ginsenoside Rg3 regulates S-nitrosylation of the NLRP3 inflammasome via suppression of iNOS.[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2015-08-07] -  An increased level of IL-6 suppresses NK cell activity in peritoneal fluid of patients with endometriosis via regulation of SHP-2 expression.[ HUMAN REPRODUCTION,2014-10-10] -  MicroRNA-150 modulates intracellular Ca 2+ levels in naive CD8+ T cells by targeting TMEM20.[SCIENTIFIC REPORTS,2017-06-01] -  The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein.[ NATURE COMMUNICATIONS,2014-05-01] -  Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity.[THERANOSTICS,2017-01-11]

Patent

-  티오레독신-결합 단백질을 유효성분으로 포함하는 약학적 조성물 및 이의 용도[2016-02-24] -  줄기세포로부터 IL-22를 생산하는 자연살해세포 분화 방법[2015-07-02] -  miR-150의 발현을 조절하여 자연살해세포의 세포독성을 증가시키는 방법[2016-06-12] -  섬유아세포로부터 조혈줄기세포로의 직접 역분화 유도 방법[2015-09-07] -  VDUP1을 유효성분으로 포함하는 내독소 쇼크 억제용 조성물[2015-05-19] -  탄시논을 유효성분으로 함유하는 자연살해세포 분화 또는 활성 증진용 조성물[2014-05-22] -  제대혈 CD14 양성 단핵세포로부터 자연살해세포 분화 및 증식 방법[2014-09-29]