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Bae, Kwang-Hee(Professor)

INFO

  • AffiliationKRIBB School
  • Majors Bioscience
    (Functional Genomics)
  • Contact Information042-860-4268
  • Major생물과학과
  • DegreePh.D.
  • Highest Level of Education한국과학기술원
  • E-Mail

Field of Research

Obestity and metabolic disorders, Proteomics, Stem cell differentiationa and regulation, Biomarkers

Research Results

-  배광희 등, Human zinc fingers as modular building blocks to construction of artificial transcription factors, Nature Biotechnology, 2003.03.15 -  배광희 외, Far upstream element-binding protein, a novel caspase substrate, acts as a cross-talker between apoptosis and c-myc oncogene, Oncogene, 2009.02.16 -  배광희 외, Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity, J. Lipid Res. 2012.09.15

Treatise

-  Proteomic analysis of the effect of retinoic acids on the human brest cancer cell line MCF-7[ MOLECULAR BIOLOGY REPORTS,2014-03-01] -  Selection of aptamers for mature white adipocytes by cell selex using flow cytometry[PLOS ONE,2014-05-20] -  Identification of novel binding partners for caspase-6 using a proteomic approach[JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,2014-05-31] -  Expression of the pro-domain-deleted active form of caspase-6 in Escherichia coli[JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,2014-05-31] -  A conserved mechanism for binding of p53 DNA-binding domain and anti-apoptotic Bcl-2 family proteins[ MOLECULES AND CELLS,2014-03-31] -  Identification of lactoferrin as a human dedifferentiation factor through the studies of reptile tissue regeneration mechanisms[ JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,2014-06-30] -  Identification of DNA APTAMERS TOWARD EPITHELIAL CELL ADHESION MOLECULE VIA CELL-SELEX[ MOLECULES AND CELLS,2014-10-30] -  Hax-1 regulates E3 ubiquitin ligase activity of cIAPs by promoting their dimerization[ONCOTARGET,2014-11-01] -  Reptin regulates pluripotency of embryonic stem cells and somatic cell reprogramming through Oct4-dependent mechanism[ STEM CELLS,2014-11-30] -  Intracellular annexin A2 regulates NF-kB signaling by binding to the p50 subunit: implications for gemcitabine resistance in pancreatic cancer[CELL DEATH & DISEASE,2015-01-31] -  Structural convergence of unstructured p53 family transactivation domains in MDM2 recognition[CELL CYCLE,2015-02-15] -  Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody[ BIOMATERIALS,2015-02-17] -  Dusp4 regulates neuronal differentiation and calcium homeostasis by modulating Erk1/2 phosphorylation[ STEM CELLS AND DEVELOPMENT,2015-03-31] -  Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma[ONCOTARGET,2015-06-01] -  A lactate-induced response to hypoxia[ CELL,2015-04-16] -  Isolation of foreign material-free endothelial progenotor cells using CD31 aptamer and therapeutic application for ischemic injury[PLOS ONE,2015-07-06] -  Identification of the regulators binding to the upstream region of glxR in corynebacterium glutamicum[JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,2015-08-31] -  Histone H3 is digested by granzyme A during compromised cell death in the Raji cells[JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,2015-09-30] -  Silica nanoparticles inhibit brown adipocyte differentiation via regulation of p38 phosphorylation[ NANOTECHNOLOGY,2015-10-05] -  MAP kinase phosphatase 3 inhibots brown adipocyte differentiation via regulation of Erk phosphorylation[ MOLECULAR AND CELLULAR ENDOCRINOLOGY,2015-08-29] -  Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesis[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2015-10-09] -  Loss of NDRG2 promotes epithelial-mesenchymal transition of gallblader carcinoma cells through MMP=19-mediated slug expression[ JOURNAL OF HEPATOLOGY,2015-12-01] -  c-Jun regulates adipocyte differentiation via the KLF15-mediated mode[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2016-02-15] -  Profiling analysis of protein tyrosine phosphatases during neuronla differenitation[ NEUROSCIENCE LETTERS,2016-02-01] -  Set7/9, a methyltransferase, regulates the thermogenic program during brown adipocyte differentiation through the modulation of p53 acetylation[ MOLECULAR AND CELLULAR ENDOCRINOLOGY,2016-04-29] -  Methyltransferase and demethylase profiling studies during brown adipocyte differentiation[BMB REPORTS,2016-07-31] -  Structural insight into the critical role of the N-terminal region in the catalytic activity of dual-specificity phosphatase 26[PLOS ONE,2016-09-01] -  High-resolution crystal structure of the PDZ1 domain of human protein tyrosine phosphatase PTP-Bas[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2016-08-18] -  Histone H4 is cleaved by granzyme A during staurosporine-induced cell death in B-lymphoid Raji cells[BMB REPORTS,2016-10-01] -  Graphene oxide induces apoptotic cell death in endothelial cells by activating autophagy via calcium-dependent phophorylation of c-Jun N-terminal kinases[ACTA BIOMATERIALIA,2016-09-15] -  Metabolic adaptation in obesity and type II diabetes: myokines, adipokines and hepatokones[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2016-12-22] -  Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranfin-induced cell death through activation of autophagy in gastric cancer[ONCOTARGET,2016-11-15]

Patent

-  성숙지방세포에 특이적으로 결합하는 핵산 앱타머 및 이의용도[2015-08-11] -  코플린-1을 이용한 갈색지방세포 분화조절 방법[2016-09-27] -  EpCAM 에 특이적으로 결합하는 핵산 앱타머 및 이의 용도[2016-07-18] -  PTP-RE를 이용한 갈색 지방세포 분화조절 방법[2015-11-20]