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Kim Seon Young(Professor)

INFO

  • AffiliationKRIBB School
  • Majors Bioscience
    (Functional Genomics)
  • Contact Information042-879-8116
  • Major미생물학
  • DegreePh.D.
  • Highest Level of Education서울대학교
  • E-Mail

Field of Research

genomics, bioinformatics, epigenomics

Research Results

-  Kim SK, Kim JH, Yun SJ, Kim WJ, and Kim SY* (2014) APPEX: analysis platform for the identification of prognostic gene signatures in cancer Bioinformatics, 30(22): 3284-6 -  Kim M, Park YK, Kang TW, Lee SH, Rhee YH, Park JL, Lee D, Lee D, Kim SY* and Kim YS* (2014) Dynamic changes in DNA methylation and hydromethylation when hES cells undergo differentiation toward a neuronal lineage, Hum Mol Genet: 23(3):657-67 -  Lee KS, Park JL, Lee K, Richardson LE, Johnson BH, Lee HS, Lee JS, Kim SB, Kwon OH, Song KS, Kim YS, Ashktorab H, Smoot DT, Jeon SH*, Kim SY*, and Lee YS* (2014) nc886, a non-coding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer Oncotarget, 5(11): 3944-3955

Treatise

-   Improving gene-set enrichment analysis of RNA-seq data with small replicates[PLOS ONE,2016-11-09] -   Genome-wide functional analysis using the Barcode Sequence Alignment and Statistical Analysis (Barcas) tool[BMC BIOINFORMATICS,2016-12-23] -   A proteogenomic approach for protein-level evidence of genomic variants in cancer cellsl[SCIENTIFIC REPORTS,2016-10-13] -  GSF2 deletion increases lactic acid tolerance by alleviating glucose repression in Saccharomyces cerevisiae[SCIENTIFIC REPORTS,2016-10-06] -   Infection-specific phosphorylation of glutamyl-prolyl tRNA synthetase induces antiviral immunity[ NATURE IMMUNOLOGY,2016-11-01] -  Identification of molecular subtypes and significantly mutated genes in gastric cancer using next-generation sequencing[TRANSLATIONAL CANCER RESEARCH,2016-06-01] -  Genomic and epigenomic heterogeneity in molecular subtypes of gastric cancer[WORLD JOURNAL OF GASTROENTEROLOGY,2016-01-21] -  APPEX: analysis platform for the identification of prognostic gene signatures in cancer[ BIOINFORMATICS,2014-11-15] -  Identification of body fluid-specific DNA methylation markers for forensic science[FORENSIC SCIENCE INTERNATIONAL-GENETICS,2014-11-01] -  Genome-wide profiling of the microRNA-mRNA regulator network in skeletal muscle in aging [AGING-US,2014-07-01] -  A nineteen gene-based risk score classifier predicts prognosis of colorectal cancer patients[MOLECULAR ONCOLOGY,2014-12-01] -  Microarray screening and qRT-PCR evaluation of microRNA markers for forensic body fluid identification[ ELECTROPHORESIS,2014-11-01] -  nc886, a non-coding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer[ONCOTARGET,2014-06-15] -  Differences of gastric mucosal microbiota profiling in patients with chronic gastritis, intestinal metaplasia, an gastric cancer using pyrosequencing methods[ HELICOBACTER,2014-12-01] -  REGNET: Mining context-specific human transcription networks using composite genomic information[BMC GENOMICS,2014-06-09] -  Epigenetic silencing of BTB and CNV homology 2 and concerted promoter CpG methylation in gastric cancer,[ CANCER LETTERS,2014-09-01] -  Epigenetic silencing of the non-coding RNA nc886 provokes oncogenes during human eosphageal tumorigenesis[ONCOTARGET,2014-06-15] -  Integrative genomics analysis reveals the multilevel dysregulation and oncogenic characteristics of TEAD4 in gastric cancer[ CARCINOGENESIS,2014-05-01] -  Single-nucleotide polymorphisms in the vascular endothelial growth factor pathway and outcomes of patients treated with first-line cytotoxic chemotherapy combined with bevacizumab for advanced colorectal cancer.[ ONCOLOGY,2014-12-01] -   LATS-YAP/TAZ controls lineage specification by regulating TGFb signaling and Hnf4a expression during liver development[NATURE COMMUNICATIONS,2016-06-30] -  ZKSCAN3 facilitates liver metastasis of colorectal cancer associated with CEA-expressing tumors[ ANTICANCER RESEARCH,2016-07-01] -  Feasibility of novel PPP1R15A and proposed ANXA11 single nucleotide polymorphisms as predictive markers for bevacizumab regimen in metastatic colorectal cancer.[ JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,2016-08-01] -  Complex Behavior of ALDH1A1 and IGFBP1 in Liver Metastasis from a Colorectal Cancer.[PLOS ONE,2016-05-06] -  Specific expression and methylation of SLIT1, SLIT2, SLIT3, and miR-218 in gastric cancer subtypes [ INTERNATIONAL JOURNAL OF ONCOLOGY,2016-06-01] -   Identification and evaluation of age-correlated DNA methylation markers for forensic use[FORENSIC SCIENCE INTERNATIONAL-GENETICS,2016-07-23] -  Integrated epigenomic analyses of enhancer as well as promoter regions in gastric cancer [Oncotarget,2016-05-03] -  Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites[Oncotarget,2016-02-16] -  Gpr171 expression enhances proliferation and metastasis of lung cancer cells[Oncotarget,2016-02-16] -   Integrated Genomic Analysis of Recurrence-Associated Small Non-coding RNAs in Oesophageal Cancer[ GUT,2017-02-01] -  MRTF potentiates TEAD-YAP transcriptional activity causing metastasis[ EMBO JOURNAL,2017-02-15] -  A late-lineage murine neutrophil precursor populationk exhibits dynamic changes during demand-adapted granulopoiesis[SCIENTIFIC REPORTS,2017-01-06] -  Epigenetic regulation of noncoding RNA transcription by mammalian RNA polymerase III[EPIGENOMICS,2017-02-01] -  A basal-like breast cancer-specific role for SRF-IL16 in YAP-induced cancer stemness[NATURE COMMUNICATIONS,2015-12-16] -  Decrease of 5hmC in gastric cancers is associated with TET1 silencing due to DNA methylation and bivalent histone marks at TET1 CpG island 3'-shore[ONCOTARGET,2015-11-10] -  The c-MET network as novel prognostic marker for predicting bladder cancer patients with an increased risk of developing aggressive disease[PLOS ONE,2015-01-30] -  The c-MET network as novel prognostic marker for predicting bladder cancer patients with an increased risk of developing aggressive disease[Genes and Development,2015-08-01] -  Roles of DPY30 in the proliferation and motility of gastric cancer cells[PLOS ONE,2015-06-06] -  SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase[ NUCLEIC ACIDS RESEARCH,2015-06-27] -   MED30 regulates the proliferation and motility of gastric cancer cells[PLOS ONE,2015-06-25] -  Genome-wide mutation profiles of colorectal tumors and associated liver metastases at the exome and transcriptome levels[ONCOTARGET,2015-09-08] -  Ctbp2 modulates NuRD-mediated deacetylation of H3K27 and facilitates PRC2-mediated H3K27me3 in active ESC genes during exit from pluripotency[STEM CELLS,2015-08-01] -  Vitamin C Facilitates Dopamine Neuron Differentiation in Fetal Midbrain Through Tet1- aND Jmjd3-Dependent Epigenetic Control Manner[ STEM CELLS,2015-04-01] -  ATOH1 can regulate the tumorigenicity of gastric cancer cells by inducing the differentiation of cancer stem cells[PLOS ONE,2015-05-07] -  Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway [ SCIENCE,2015-03-14] -  Epigenetic regulation of KLHL34 predictive of pathologic response to preoperative chemoradiation therapy in rectal cancer patients[ INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS,2016-03-01]