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Kyu-Sun Lee(Professor)

INFO

  • AffiliationKRIBB School
  • Majors Bioscience
    (Functional Genomics)
  • Contact Information042-860-4429
  • Major동물학
  • DegreePh.D.
  • Highest Level of Education중앙대학교
  • E-Mail

Field of Research

Develop therapeutics for age-related diseases

Research Results

-  이규선외/Polo Kinase Phosphorylates Miro to Control ER-Mitochondria Contact Sites and Mitochondrial Ca(2+) Homeostasis in Neural Stem Cell Development/Developmental Cell/2016.08 -  이규선외/Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway/Genes&Development/2013.12 -  이규선외/Drosophila short neuropeptide F signalling regulates growth by ERK-mediated insulin signalling/NatureCellBiology/2008.04

Treatise

-  Targeting PINK1 and MQC in brain tumors[ONCOTARGET,2014-05-30] -  The myriad roles of Miro in the nervous system: axonal transport of mitochondria and beyond[FRONTIERS IN CELLULAR NEUROSCIENCE,2014-10-28] -  Curcumin mitigates accelerated aging after irradiation in Drosophila by reducing oxidative stress[BIOMED RESEARCH INTERNATIONAL,2015-03-15] -  Genome-wide microRNA screening reveals that the evolutionary conserved miR-9a regulates body growth by targeting sNPFR1/NPYR[NATURE COMMUNICATIONS,2015-07-03] -  Polo Kinase Phosphorylates Miro to Control ER-Mitochondria Contact Sites and Mitochondrial Ca(2+) Homeostasis in Neural Stem Cell Development[DEVELOPMENTAL CELL,2016-04-18] -  A chemical with proven clinical safety rescues Down-syndrome-related phenotypes in through DYRK1A inhibition[DISEASE MODELS & MECHANISMS,2016-08-01] -  High fat diet-induced TGF-beta/Gbb signaling provokes insulin resistance through the tribbles expression[SCIENTIFIC REPORTS,2016-08-03] -  The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain[ PLOS GENETICS,2017-05-17] -  The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain[ PLOS GENETICS,2017-05-17]

Patent

-  인간신경펩티드수용체 형질전환 초파리를 이용한 비만 치료제 스크리닝 방법[2014-04-30] -  인간 DYRK1A 유전자 형질전환 초파리를 이용한 치료제 스크리닝 방법[2014-09-29] -  CX-4945를 유효성분으로 함유하는 퇴행성 뇌질환 예방 및 치료용약학적조성물[2017-02-03]