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이명규 교수

Lee Myung Kyu

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  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명공학
    (나노바이오공학)
  • 연락처042-860-4169
  • 출신전공생화학
  • 학위박사
  • 최종출신대학한국과학기술원
  • 이메일

연구분야

대표연구실적

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논문(최근 5년)

-  Selective Small Molecule Probes for the Hypoxia Inducible Factor (HIF) Prolyl Hydroxylases[ACS chemical biology,2013-07-19] -  Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion[Organic & biomolecular chemistry,2013-02-07] -  Novel cell penetrating peptides with multiple motifs composed of RGD and its analogs[Biochemical and biophysical research communications,2013-03-08] -  Differential in vitro and cellular effects of iron chelators for hypoxia inducible factor hydroxylases[Journal of cellular biochemistr,2013-04-01] -  Ethanol treatment a Non-extrusion method for asymmetric liposome size optimization[DARU-JOURNAL OF FACULTY OF PHARMACY,2013-04-18] -  PTPRT regulates the interaction of Syntaxin-binding protein 1 with Syntaxin 1 through dephosphorylation of specific tyrosine residue.[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2013-09-13] -  TMPRSS4 upregulates uPA gene expression through JNK signaling activation to induce cancer cell invasion[ CELLULAR SIGNALLING,2014-02-03] -  TMPRSS4 induces cancer cell invasion through pro-uPA processing[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2014-03-28] -  Filopodial morphology correlates to the capture efficiency of primary T-cells on nanohole arrays[JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,2014-06-02] -  Dependence of filopodia morphology and the separation efficiency of primary CD4+ T-lymphocytes on nanopillars[ ANALYTICAL CHEMISTRY,2014-06-03] -  Refolded scFv antibody fragment against myoglobin shows rapid reaction kinetics[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2014-12-18] -  Enhanced tumor-targeted gene delivery by bioreducible polyethylenimine tethering EGFR divalent ligands[Biomaterials Science,2016-02-17] -  Purification and characterization of Fab fragments with rapid reaction kinetics against myoglobin[ BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,2015-01-03] -  Highly efficient encapsulation of anionic small molecules in asymmetric liposome particles[한국진공학회지,2015-11-30] -  Covalent and Oriented Surface Immobilization of Antibody using Photoactivatable Antibody Fc-Binding Protein Expressed in Escherichia coli[ ANALYTICAL CHEMISTRY,2016-10-04]

특허(최근 5년)

-  광활성 메티오닌 모사체 도입 단백질 G 변이체[2016-02-23] -  광활성 메티오닌 모사체 표지 단백질 생합성을 위한 메티오닐tRNA합성효소 변이체[2015-12-29] -  압출공정 없이 핵산 함유 나노 리포솜을 제조하는 방법[2015-02-10] -  핵산 및 친수성 음이온 화합물의 고효율 포획을 위한 비대칭 리포솜 및 이의 제조 방법[2012-11-01] -  ASYMMETRIC LIPOSOMES FOR THE HIGHLY EFFICIENT ENCAPSULATION OF NUCLEIC ACIDS AND HYDROPHILIC ANIONIC COMPOUNDS, AND METHOD FOR PREPARING SAME [2016-05-03] -  나노입자가 융합된 FRET 센서 및 이를 이용한 파이토에스트로겐을 고감도로 검출하는 방법[2016-06-13] -  세포포획용 고배향성 항체 고정을 위한 아가로우즈 필름 코팅 마이크로포스트 플레이트[2017-07-28] -  세포포획용 고배향성 항체 고정을 위한 아가로우즈 필름 코팅 마이크로포스트 플레이트[2017-07-28]