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Lee Daehee(Professor)

INFO

  • AffiliationKRIBB School
  • Majors Biotechnology
    (Biosystems and Bioengineering)
  • Contact Information042-879-8225
  • Major생물공학
  • DegreePh.D.
  • Highest Level of Education서울대학교
  • E-Mail
Personal Homepage

Field of Research

Synthetic Biology & Metabolic Engineering

Research Results

-  Seong Keun Kim*, Dae-Hee Lee*, Oh Cheol Kim, Jihyun F. Kim, and Sung Ho Yoon, 2017, Tunable control of an Escherichia coli expression system for the overproduction of membrane proteins by titrated expression of a mutant lac repressor, ACS Synthetic Biology 6(9): 1766?1773. -   Seong Keun Kim, Haseong Kim, Woo-Chan Ahn, Kwang-Hyun Park, Eui-Jeon Woo, Dae-Hee Lee*, Seung-Goo Lee*, 2017, Efficient transcriptional gene repression by type V-A CRISPR-Cpf1 from Eubacterium eligens, ACS Synthetic Biology 6(7):1273?1282. -  Gui Hwan Han, Wonjae Seong, Yaoyao Fu, Paul K. Yoon, Seong Keun Kim, Soon-Jin Yeom, Dae-Hee Lee*, Seung-Goo Lee*, 2017, Leucine zipper-mediated targeting of multi-enzyme cascade reactions to inclusion bodies in Escherichia coli for enhanced production of 1-butanol, Metabolic Engineering 40:41?49. ?

Treatise

-  Optimizing promoters and secretory signal sequences for producing ethanol from inulin by recombinant Saccharomyces cerevisiae carrying Kluyveromyces marxianus inulinase[BIOPROCESS AND BIOSYSTEMS ENGINEERING,2014-08-21] -  A novel psychrophilic alkaline phosphatase from the metagenome of tidal flat sediments [BMC BIOTECHNOLOGY,2015-01-31] -  Rationmetric analyses at critical temperatures can magnify the signal intensity of FRET-based sugar sensors with periplasmic binding proteins[BIOSENSORS & BIOELECTRONICS,2015-10-01] -  Comparative genomics and parallel evolution reveals toxicity escape mechanisms caused by membrane protein overexpression?[SCIENTIFIC REPORTS,2015-11-04] -  Toward complete bacterial genome sequencing through the combined use of multiple next-generation sequencing platforms[JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,2015-10-14] -  Fumarate-mediated persistence of Escherichia coli against antibiotics[ANTIMICROBIAL AGENTS AND CHEMOTHERAPY,2016-04-01] -  A cell-cell communication-based screening system for novel microbes with target enzyme activities?[ACS SYNTHETIC BIOLOGY,2016-07-25] -  CRISPR interference-guided balancing of a biosynthetic mevalonate pathway increases terpenoid production[METABOLIC ENGINEERING,2016-11-01] -  Fermentative production and direct extraction of (-)-alpha-bisabolol in?metabolically engineered?Escherichia coli[MICROBIAL CELL FACTORIES,2016-11-08] -  Long-term stable and tightly controlled expression of recombinant proteins in antibiotics-free conditions[PLOS ONE,2016-12-01] -  Production of D-ribose by metabolically engineered?Escherichia?coli??[PROCESS BIOCHEMISTRY,2017-01-02] -  Leucine zipper-mediated targeting of multi-enzyme cascade reactions to inclusion bodies in Escherichia coli for enhanced production of 1-butanol[METABOLIC ENGINEERING,2017-03-01] -  Controlled aggregation and increased stability of beta-glucuronidase by cellulose binding domain fusion[PLOS ONE,2017-01-18] -  Efficient transcriptional gene repression by type V-A CRISPR-Cpf1 from Eubacterium eligens[ACS SYNTHETIC BIOLOGY,2017-04-04] -  Tunable control of an Escherichia coli expression system for the overproduction of membrane proteins by titrated expression of a mutant lac repressor[ACS SYNTHETIC BIOLOGY,2017-05-19] -  Enhanced production of xylitol from xylose by expression of Bacillus?subtilis arabinose:H+?supporter and Scheffersomyces stipitis xylose reductase in recombinant Saccharomyces cerevisiae?[ENZYME AND MICROBIAL TECHNOLOGY,2017-12-01] -  CRISPR interference-guided multiplex repression of endogenous competing pathway genes for redirecting metabolic flux in Escherichia coli [MICROBIAL CELL FACTORIES,2017-11-03] -  Evolution of enzymes with new specificity by high-throughput screening using DmpR-based genetic circuits and multiple flow cytometry rounds[SCIENTIFIC REPORTS,2018-02-08] -  Development of a novel cellulase biosensor that detects crystalline cellulose hydrolysis using a transcriptional regulator[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2018-01-01] -  Tabrizicola fusiformis sp. nov., isolated from an industrial wastewater treatment plant [INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY,2018-04-06]

Patent

-  LacI 단백질 변이체를 이용한 독성 단백질의 생산 방법[2014-07-08] -  재설계 유전자회로를 이용한 아미노카프론산의 감지 및 정량 방법[2017-08-31] -  신규 카프로락탐 전환 효소 및 이를 이용한 카프로락탐 생산 방법[2017-03-07] -  단백질 융합 디스플레이 기술을 이용한 물질 간 상호작용 고속분석 방법[2017-04-28] -  재설계 유전자회로를 이용한 카프로락탐의 감지 및 정량 방법[2017-03-31] -  재설계 유전자회로를 이용한 섬유소분해효소 활성의 신규 탐색 및 정량방법[2016-07-07] -  유전자회로 설계용 부품뱅크[2015-02-23]