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  • 소속캠퍼스한국화학연구원 스쿨
  • 전공 화학소재 및 공정
    (그린화학공정)
  • 연락처042-860-7186
  • 출신전공생유기화학
  • 학위박사
  • 최종출신대학Yale University
  • 이메일

연구분야

비대칭촉매, 광학활성물질의 합성, 생촉매반응

Asymmetric catalysis, Enantioselective synthesis of biologically active molecules, Chemoenzymatic reaction

대표연구실적

-  Potential Pitfalls of Using Epichlorohydrin as Starting Material for Oxazolidinone Antibacterials, Bull. Korean Chem. Soc. 2013, 34, 641 -  Protective group-free synthesis of new chiral diamines via direct azidation of 1,1-diaryl-2-aminoethanols, RSC Adv. 2013, 3, 3526 -  Regioselective Synthesis of Trialkylpyrazines via Nickel-Catalyzed Negishi Cross-Coupling of Pyrazine Triflate, Synthesis 2012, 44, 1631

논문(최근 5년)

-  Entry to Highly Hindered Chiral β-Amino Triazoles Bearing a gem-Diaryl Group by Azide-alkyne Click Chemistry[ BULLETIN OF THE KOREAN CHEMICAL SOCIETY,2014-05-29] -  A Practical Synthesis of the Antidepressant (S)-Duloxetine[ BULLETIN OF THE KOREAN CHEMICAL SOCIETY,2014-05-29] -  6-Trifluoromethyl-2-thiouracil possesses anti-Toxoplasma gondii effect in vitro and in vivo with low hepatotoxicity[ EXPERIMENTAL PARASITOLOGY,2014-08-11] -  Copper-catalyzed regio- and stereoselective ring-opening of cyclic sulamidates with Grignard reagents assisted by LiCl[ ADVANCED SYNTHESIS & CATALYSIS,2015-08-10] -  Effieient and convenient synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives mediated by L-proline[ SYNTHETIC COMMUNICATIONS,2016-08-24] -  Complete saccharification of cellulose through chemo-enzymatic hydrolysis[BIOMASS & BIOENERGY,2016-08-11] -  Mitsunobu reactions of cis/trans-3- and -4-hydroxy-2-aminomethylpyrrolidine derivatives[ BULLETIN OF THE KOREAN CHEMICAL SOCIETY,2015-08-10] -  Influence of steric demand on ruthenium-catalyzed cycloaddition of sterically hindered azides[RSC ADVANCES,2017-02-06] -  Aqueous fraction of cucumber plant extract detoxifies paraquat phytotoxicith as a superoxide scavenger[JOURNAL OF FOOD PROCESSING AND PRESERVATION,2017-01-15] -  Small molecules that allosterically inhibit p21-activated kinase activity by binding to the regulatory p21-binding domain[ EXPERIMENTAL AND MOLECULAR MEDICINE,2016-05-09] -  Identification of a novel cellulose-binding domain within the endo-b-1,4-xylanase KRICT PX-3 from Paenibacillus terrae HPL-003[ ENZYME AND MICROBIAL TECHNOLOGY,2016-08-10] -  Synthesis of functionalized 4H-3,1-benzoxazines through chemoselective reduction of benzoxazin-4-ones[ BULLETIN OF THE KOREAN CHEMICAL SOCIETY,2017-03-13] -  One-pot synthesis of four-coodinate boron(III) complexes by the ligand-promoted organic group migration betwwen boronic acids[SCIENTIFIC REPORTS,2017-03-14] -  A novel pyrazole derivative protects from ovariectomy-induced osteoporosis through the inhibition of NADPH oxidase[SCIENTIFIC REPORTS,2016-05-09] -  Triazole phenyl sulfides: 8-amino-7-oxononanoate synthase inhibitors as potential herbicide[ PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,2015-08-27]

연구과제 수행 실적

아미노산 기반 DKP의 합성과 활용