이해준 교수

Hae-June Lee

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  • 소속캠퍼스한국원자력의학원
  • 전공 방사선종양의과학
  • 연락처02-970-1638
  • 출신전공수의학과(수의해부학)
  • 학위박사
  • 최종출신대학전남대학교
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연구분야

방사선생물학

Radiation Biology

대표연구실적

-  Lee HJ, Yoon C, Schmidt B, Park DJ, Zhang AY, Erkizan HV, Toretsky JA, Kirsch DG, Yoon SS/Combining PARP-1 inhibition and radiation in Ewing sarcoma results in lethal DNA damage/Mol Cancer Ther/ 2013 Nov -  Lee HJ, Kwon HC, Chung HY, Lee YJ, Lee YS//Recovery from radiation-induced bone marrow damage by HSP25 through Tie2 signaling/Int J Radiat Oncol Biol Phys/2012 Sep 1 -  Jeong YJ, Son Y, Han NK, Choi HD, Pack JK, Kim N, Lee YS, Lee HJ/Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice/Int J Mol Sci/2018 Jul 19

논문(최근 5년)

-  Trastuzumab Induced Chemobrain, Atorvastatin Rescued Chemobrain with Enhanced Anticancer Effect and without Hair Loss-Side Effect.[JOURNAL OF CLINICAL MEDICINE,2019-02-11] -  Oridonin Enhances Radiation-Induced Cell Death by Promoting DNA Damage in Non-Small Cell Lung Cancer Cells[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2018-08-13] -  Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2018-07-19] -  Auranofin, an Anti-rheumatic Gold Drug, Aggravates the Radiation-Induced Acute Intestinal Injury in Mice.[FRONTIERS IN PHARMACOLOGY,2019-04-24] -  Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation.[Cell Death and Differentiation,2019-05-26] -  Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization.[Nature Communications,2018-11-30] -  Early Detection of Aβ Deposition in the 5xFAD Mouse by Amyloid PET.[CONTRAST MEDIA & MOLECULAR IMAGING,2018-02-28] -  Proinvasive extracellular matrix remodeling in tumor microenvironment in response to radiation.[Oncogene,2018-03-21] -  Aβ pathology downregulates brain mGluR5 density in a mouse model of Alzheimer.[Neuropharmacology,2018-03-21] -  FYN promotes mesenchymal phenotypes of basal type breast cancer cells through STAT5/NOTCH2 signaling node.[Oncogene,2018-01-19] -  Long-term RF exposure on behavior and cerebral glucose metabolism in 5xFAD mice.[Neuroscience Letters,2018-02-14] -  Silibinin attenuates radiation-induced intestinal fibrosis and reverses epithelial-to-mesenchymal transition.[Oncotarget,2017-09-02] -  Geranylgeranylacetone Ameliorates Intestinal Radiation Toxicity by Preventing Endothelial Cell Dysfunction.[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2017-10-07] -  NQO1 inhibits proteasome-mediated degradation of HIF-1α.[Nature Communications,2016-12-14] -  Identification of radiation response genes and proteins from mouse pulmonary tissues after high-dose per fraction irradiation of limited lung volumes.[INTERNATIONAL JOURNAL OF RADIATION BIOLOGY,2017-02-01] -  Geranylgeranylacetone alleviates radiation-induced lung injury by inhibiting epithelial-to-mesenchymal transition signaling[MOLECULAR MEDICINE REPORTS,2016-06-01] -  Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer.[Oncotarget,2016-08-16] -  1950 Hz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice.[Bioelectromagnetics,2016-09-30] -  Silicon Dioxide Nanoparticles Enhance Endotoxin-Induced Lung Injury in Mice[Molecules,2018-09-03] -  Effects of NOX1 on fibroblastic changes of endothelial cells in radiation-induced pulmonary fibrosis[Molecular Medicine Reports,2016-04-05] -  HSPB1 Inhibits the Endothelial-to-Mesenchymal Transition to Suppress Pulmonary Fibrosis and Lung Tumorigenesis.[CANCER RESEARCH,2016-03-01] -  PKCδ activated by c-MET enhances infiltration of human glioblastoma cells through NOTCH2 signaling[Oncotarget,2016-01-26] -  Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules.[Oncotarget,2016-07-16]