장미희 교수

Mihue Jang

INFO

  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
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연구분야

항암 치료, 면역 치료, 유전자 가위, 유전자 에디팅, 세포 입양 치료

Anti-cancer therapy, Immunotherapy, CRISPR/Cas9, Gene editing, Adoptive cell therapy

대표연구실적

-  Ju et al/A carrier-free multiplexed gene editing system applicable for suspension cells/Biomaterials/2019.06 -  Kim et al/Simple in Vivo Gene Editing via Direct Self-Assembly of Cas9 Ribonucleoprotein Complexes for Cancer Treatment/ACS NANO/2018.07 -  Jang et al/Design of a platform technology for systemic delivery of siRNA to tumours using rolling circle transcription/Nature communications/2015

저서(최근 5년)

-  Rolling Circle Transcription for the Self-Assembly of Multimeric RNAi Structures and Its Applications in Nanomedicine[2017-07-21]

논문(최근 5년)

-  A carrier-free multiplexed gene editing system applicable for suspension[BIOMATERIALS,2019-06-25] -  Simple in Vivo Gene Editing via Direct Self-Assembly of Cas9 Ribonucleoprotein Complexes for Cancer Treatment [ACS NANO,2018-07-20] -  MiR195 and miR 497 suppress tumorigenesis in lung cancer by inhibiting SMURF2 induced TGF β receptor ubiquitination[MOLECULAR ONCOLOGY,2019-10-03] -  Stemness-Attenuating miR-503-3p as a Paracrine Factor to Regulate Growth of Cancer Stem Cells [STEM CELLS INTERNATIONAL,2018-04-04] -  A Novel Secretory Vesicle from Deer Antlerogenic Mesenchymal Stem Cell-Conditioned Media (DaMSC-CM) Promotes Tissue Regeneration [STEM CELLS INTERNATIONAL,2018-03-25] -  Cancer-derived exosomes as a delivery platform of CRISPR/Cas9 confer cancer cell tropism-dependent targeting[JOURNAL OF CONTROLLED RELEASE,2017-09-12] -  A RNA nanotechnology platform for a simultaneous two-in-one siRNA delivery and its application in synergistic RNAi therapy[SCIENTIFIC REPORTS,2016-08-26]

특허(최근 5년)

-  유전자 표적의 동시 사일런싱이 가능한 2 종류 siRNA 동시 전달용 RNA 나노입자 및 이를 포함하는 전달체 [2017-10-12]