이미옥 교수

Mi-Ok Lee

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처042-879-8475
  • 출신전공의생명공학
  • 학위박사
  • 최종출신대학차의과학대학교
  • 이메일

연구분야

줄기세포, 질병모델

Stem Cell, Disease modeling

대표연구실적

-  MO Lee, CH You, MY Son, YD Kim, H Jeon, JS Chang, YS Cho Pro-fibrotic effects of PFKFB4-mediated glycolytic reprogramming in fibrous dysplasia. Biomaterials 2016 Aug 26 -  Mi-Ok Lee1#, Kwang Bo Jung1,2, Seong-Jae Jo1,2, Sung-Ae Hyun3, Kyoung-Sik Moon3, Joung-Wook Seo3, Sang-Heon Kim4,5# and Mi-Young Son1,2# Modelling cardiac fibrosis using three-dimensional cardiac microtissues derived from human embryonic stem cells J. Biol. Eng., 2019 Feb 13 -  Young-Hyun Go1, Changjin Lim2, Ho-Chang Jeong1, Ok-Seon Kwon, Sungkyun Chung, Haeseung Lee, Wankyu Kim, Young-Ger Suh, Woo Sung Son, Mi-Ok Lee#, Hyuk-Jin Cha# and Seok-Ho Kim# Structure-activity relationship analysis of YM155 for inducing selective cell death of human pluripotent stem cells, Frontiers in Chemistry, 2019 may 16

논문(최근 5년)

-  In situ label-free quantification of human pluripotent stem cells with electrochemical potential[BIOMATERIALS,2016-01-31] -  Generation and characterization of integration-free induced pluripotent stem cells from patients with autoimmune disease[EXPERIMENTAL AND MOLECULAR MEDICINE,2016-05-01] -  Biomarker discovery by modeling Behcet's disease with patient-specific human induced pluripotent stem cells[STEM CELLS AND DEVELOPMENT,2017-01-15] -  Distinctive genomic signature of neural and intestinal organoids from familial Parkinson's disease patient­derived induced pluripotent stem cells[NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY,2017-02-24] -  Technical approaches to induce selective cell death of pluripotent stem cells[CELLULAR AND MOLECULAR LIFE SCIENCES,2017-02-28] -  PRMT8 controls the pluripotency and mesodermal fate of human embryonic stem cells by enhancing the PI3K/AKT/SOX2 axis[STEM CELLS,2017-05-20] -  The unique spliceosome signature of human pluripotent stem cells is mediated by SNRPA1, SNRPD1, and PNN.[STEM CELL RESEARCH,2017-05-30] -  In vitro and in vivo imaging and tracking of intestinal organoids from human induced pluripotent stem cells[FASEB JOURNAL,2017-08-29] -  Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells[Oncotarget,2017-09-01] -  Clump-passaging-based efficient 3D culture of human pluripotent stem cells under chemically defined conditions[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2017-11-04] -  Comparative analysis of human embryonic stem cell?derived neural stem cells as an in vitro human model[INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE,2018-02-01] -  Interleukin-2 induces the in vitro maturation of human pluripotent stem cell-derived intestinal organoids[NATURE COMMUNICATIONS,2018-08-02] -  Selective Elimination of Culture-Adapted Human Embryonic Stem Cells with BH3 Mimetics[STEM CELL REPORTS,2018-11-13] -  Modelling cardiac fibrosis using three-dimensional cardiac microtissues derived from human embryonic stem cells[JOURNAL OF BIOLOGICAL ENGINEERING,2019-02-13] -  A SMN2 Splicing Modifier Rescues the Disease Phenotypes in an In Vitro Human Spinal Muscular Atrophy Model[STEM CELLS AND DEVELOPMENT,2019-04-01] -  Structure-activity relationship analysis of YM155 for inducing selective cell death of human pluripotent stem cells[FRONTIERS IN CHEMISTRY,2019-05-16] -  Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells[JOURNAL OF CLINICAL MEDICINE,2019-07-04] -  Generation of expandable human pluripotent stem cell-derived hepatocyte-like liver organoids[JOURNAL OF HEPATOLOGY,2019-06-21] -  Pro-fibrotic effects of PFKFB4-mediated glycolytic reprogramming in fibrous dysplasia[BIOMATERIALS,2016-11-30] -  Blood vessel formation in cerebral organoids formed from human embryonic stem cells[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2019-10-09] -  The Role of Selenium-mediated Redox Signaling by Selenophosphate Synthetase 1 (SEPHS1) in hESCs[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2019-09-27]

특허(최근 5년)

-  섬유증 질환 모델의 제조방법 및 섬유증 질환 모델의 용도[2018-03-27]