권석규 교수

Seok-Kyu Kwon

INFO

  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (생체신경과학)
  • 연락처02-958-7217
  • 출신전공
  • 학위
  • 최종출신대학
  • 이메일

연구분야

신경생물학, 미토콘드리아, 소포체, 시냅스, 라이브 이미징, 신경회로

Neurobiology, synapse, live imaging, neural circuit, mitochondria, ER

대표연구실적

-  MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size, Nat. Comm. 2018, co-first author -  ER-mitochondria tethering by PDZD8 regulates Ca2+ dynamics in mammalian neurons, Science, 2017, co-first author -  LKB1 regulates mitochondria-dependent presynaptic calcium clearance and neurotransmitter release properties at excitatory synapses along cortical axons, 2016, first author

논문(최근 5년)

-  MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size[NATURE COMMUNICATIONS,2018-11-27] -  ER-mitochondria tethering by PDZD8 regulates Ca2+ dynamics in mammalian neurons[SCIENCE,2017-11-03] -  LKB1 regulates mitochondria-dependent presynaptic calcium clearance and neurotransmitter release properties at excitatory synapses along cortical axons[PLOS BIOLOGY,2016-07-18] -  Emerging roles of mitochondria in synaptic transmission and neurodegeneration[Current Opinion in Physiology,2018-03-28] -  Organelle-specific sensors for monitoring Ca2+ dynamics in neurons[Frontiers in Synaptic Neuroscience,2016-09-16] -  Progressive decrease of mitochondrial motility during maturation of cortical axons in vitro and in vivo[CURRENT BIOLOGY,2016-10-10] -  Deficiency of aminopeptidase P1 causes behavioral hyperactivity, cognitive deficits, and hippocampal neurodegeneration[GENES BRAIN AND BEHAVIOR,2017-08-23] -  SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development[SCIENTIFIC REPORTS,2016-05-26]