신희섭 교수

Hee Sup Shin

INFO

  • 소속캠퍼스기초과학연구원
  • 전공 기초과학
  • 연락처042-878-9101
  • 출신전공유전학
  • 학위박사
  • 최종출신대학Cornell Univ
  • 이메일

연구분야

시상·대뇌피질 신경망의 의식, 인지 조절 기전 연구

Thalamocortical circuits in control of consciousness and cognition

대표연구실적

-  Jeon D, Kim S, Chetana M, Jo D, Ruley E. H, Lin S-Y, Rabah D, Kinet J-P, Shin H-S (2010. 4) Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC. N Neurosci 13(4):482-8 -  Lee S, Ahmed T, Lee S, Kim H, Choi C, Kim DS, Kim SJ, Cho J, Shin HS.(2011. 12) Bidirectional modulation of fear extinction by mediodorsal thalamic firing in mice. N Neurosci 15(2):308-14 -  Kim A, Latchoumane C, Lee S, Kim GB, Cheong E, Augustine GJ, Shin HS.(2012.12) Optogenetically induced sleep spindle rhythms alter sleep architectures in mice. Proc Natl Acad Sci U S A. 11;109(50):20673-8

논문(최근 5년)

-  Genetic factors associated with empathy in humans and mice.[Neuropharmacology,2019-01-25] -  Nerual circuits underlying a psycho-therapeutic regimen for fear disorders[NATURE,2019-02-13] -  Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions.[NATURE COMMUNICATIONS,2019-01-18] -  Stress-induced changes in social dominance are scaled by AMPA-type glutamate receptor phosphorylation in the medial prefrontal cortex[Scientific Reports,2018-10-09] -  Observational fear behavior in rodents as a model for empathy. Genes Brain Behav.[Genes, Brain and Behavior,2018-09-28] -  The Possible Role of Neurobeachin in Extinction of Contextual Fear Memory[SCIENTIFIC REPORTS,2018-09-13] -  LARGE, an intellectual disability-associated protein, regulates AMPA-type glutamate receptor trafficking and memor[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2018-07-03] -  Overcoming depression by inhibition of neural burst firing[NEURON,2018-06-06] -  A missense variant at the Nrxn3 locus enhances empathy fear in the mouse[NEURON,2018-05-02] -  The Improving Effect of HL271, a Chemical Derivative of Metformin, a Popular Drug for Type II Diabetes Mellitus, on Aging-induced Cognitive Decline[Experimental Neurobiology,2018-02-27] -  Targeted knockout of a chemokine-like gene increases anxiety and fear responses. [PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2018-01-30] -  Deficiency of a brain-specific chemokine-like molecule, SAM3, induces cardinal phenotypes of autism spectrum disorders in mice[SCIENTIFIC REPORTS,2017-11-28] -  Mice in conflict show rule-observance behavior enhancing long-term benefit[NATURE COMMUNICATIONS,2017-11-07] -  Thalamic Spindles Promote Memory Formation during Sleep through Triple Phase-Locking of Cortical, Thalamic, and Hippocampal Rhythms[NEURON,2017-07-19] -  The Ca2+-activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons.[NATURE COMMUNICATIONS,2016-12-19] -  Rodent models for studying empathy[NEUROBIOLOGY OF LEARNING AND MEMORY,2016-11-15] -  Variability in empathic fear response among 11 inbred strains of mice[Genes, Brain and Behavior,2016-02-15] -  Medial septal GABAergic projection neurons promote object exploration behavior and type 2 theta rhythm[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2016-06-07]

연구과제 수행 실적

의식, 인지 및 사회성에 대한 뇌의 기전 연구