최인표 교수

Choi, Inpyo

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처042-860-4223
  • 출신전공생물학
  • 학위박사
  • 최종출신대학University of Alabama
  • 이메일

연구분야

세포치료제, 줄기세포 기능, 면역학

Cell therapy, stem cell function, immunology

대표연구실적

-  VDUP1 is required for the development of natural killer cells.Immunity. 2005 22(2):195-208. -  TXNIP maintains the hematopoietic cell pool by switching the function of p53 under oxidative stress.Cell Metab. 2013 Jul 2;18(1):75-85. -  Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity. Nature Communications 2016 7:13674

논문(최근 5년)

-  Donor-Derived Natural Killer Cell Infusion after Human[ BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION,2016-08-08] -  Thioredoxin-interacting Protein Regulates Haematopoietic Stem Cell Ageing and Rejuvenation by Inhibiting p38 Kinase Activity[NATURE COMMUNICATIONS,2016-12-01] -  Suppressor of Cytokine Signaling 2 Negatively Regulates NK Cell Differentiation by Inhibiting JAK2 Activity[SCIENTIFIC REPORTS,2017-04-06] -  MicroRNA-150 modulates intracelluar Ca levles in naive CD8 T cells by tgargeting TMEM20[SCIENTIFIC REPORTS,2017-06-01] -  MicroRNA-150 modulates intracelluar Ca levles in naive CD8 T cells by tgargeting TMEM20[SCIENTIFIC REPORTS,2017-06-01] -  Macrophage migration inhibitory factor interacts with thioredoxin-interacting protein and induces NF-κB activity[ CELLULAR SIGNALLING,2017-06-01] -  Combining vasculature disrupting agent and Toll-like receptor 7/8 agonist for cancer therapy.[ONCOTARGET,2017-01-17] -  MicroRNA-150 modulates intracelluar Ca levles in naive CD8 T cells by tgargeting TMEM20[SCIENTIFIC REPORTS,2017-06-01] -  Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity.[THERANOSTICS,2017-01-11] -  TXNIP regulates AKT-mediated cellular senescence by direct interaction under glucose-mediated metabolic stress.[AGING CELL,2018-12-01] -  Protein phosphatase 1B dephosphorylates Rho guanine nucleotide dissociation inhibitor 1 and suppresses cancer cell migration and invasion.[CANCER LETTERS,2018-03-28] -  Prostaglandin E2 Secreted by Thyroid Cancer Cells Contributes to Immune Escape Through the Suppression of Natural Killer (NK) Cell Cytotoxicity and NK Cell Differentiation.[FRONTIERS IN IMMUNOLOGY,2018-08-09] -  TLR4/NF-κB axis induces fludarabine resistance by suppressing TXNIP expression in acute myeloid leukemia cells.[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2018-10-15] -  Thioredoxin-interacting protein-derived peptide (TN13) inhibits LPS-induced inflammation by inhibiting p38 MAPK signaling.[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2018-11-16] -  Efficient Interleukin-21 Production by Optimization of Codon and Signal Peptide in Chinese Hamster Ovarian Cells.[Journal of Microbiology and Biotechnology,2019-02-28] -  Causes and Mechanisms of Hematopoietic Stem Cell Aging.[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2019-03-13] -  Inhibition of Osteoclastogenesis by Thioredoxin-Interacting Protein-Derived Peptide (TN13).[JOURNAL OF CLINICAL MEDICINE,2019-03-29] -  Indoleamine-2,3-Dioxygenase in Thyroid Cancer Cells Suppresses Natural Killer Cell Function by Inhibiting NKG2D and NKp46 Expression via STAT Signaling Pathways.[JOURNAL OF CLINICAL MEDICINE,2019-06-12] -  TNFα and IL-1β in the synovial fluid facilitate mucosal-associated invariant T (MAIT) cell migration.[CYTOKINE,2017-07-03] -  Pseudomonas syringae evades phagocytosis by animal cells via type III effector-mediated regulation of actin filament plasticity.[APPLIED AND ENVIRONMENTAL MICROBIOLOGY,2018-06-01] -  Pharmacological Regulation of Oxidative Stress in Stem Cells[Oxidative Medicine and Cellular Longevity,2018-09-30] -  Ginsenoside Rg3 ameliorated HFD-induced hepatic steatosis through downregulation of STAT5-PPARγ[Journal of Endocrinology,2017-12-01] -  MicroRNA-150 controls differentiation of intraepithelial lymphocytes through TGF-β receptor II regulation[Journal of Allergy and Clinical Immunology,2018-04-01] -  MicroRNA-150 modulates intracelluar Ca levles in naive CD8 T cells by tgargeting TMEM20[SCIENTIFIC REPORTS,2017-06-01] -  MicroRNA-150 modulates intracelluar Ca levles in naive CD8 T cells by tgargeting TMEM20[SCIENTIFIC REPORTS,2017-06-01]

특허(최근 5년)

-  티오레독신-결합 단백질을 유효성분으로 포함하는 약학적 조성물 및 이의 용도[2016-02-24] -  miR-150의 발현을 조절하여 자연살해세포의 세포독성을 증가시키는 방법[2016-08-12] -  자연살해세포의 대량생산 방법 및 상기 방법으로 수득된 자연살해세포의 항암제로서의 용도[2019-03-06] -  티오레독신 결합단백질 유해 펩타이드 또는 이를 암호화 하는 폴리뉴클레오타이드를 유효성분으로 함유하는 노화 줄기세포의 역노화용 조성물 및 이의 용도 [2019-06-03]

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