유권 교수

Yu Kweon

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처042-860-4642
  • 출신전공발생유전학
  • 학위박사
  • 최종출신대학Bowling Green State University
  • 이메일

연구분야

분자유전학, 신경생리학, 대사질환

Molecular Genetics, Neurophysiology, Metabolism

대표연구실적

-  Genome-wide screening reveals that the evloutionary conserved miR-9a regulates body growth by targeting sNPFR1/NPYR. 2015 Nature Communications 6, 7693. -  Photoexcited porphyrins as a strong suppressor of beta-amyloid aggregation and synaptic toxicity. 2015 Angew. Chem. 54, 11472-11476. -  Drosophila short neuropeptide F signaling regulates growth by ERK mediated insulin signaling. 2008 Nature Cell Biology 10:468-475

논문(최근 5년)

-  High fat diet-induced TGF-β/Gbb signaling provokes insulin resistance through the tribbles expression[SCIENTIFIC REPORTS,2016-08-03] -  Cloning of monoacylglycerol o-acyltransferase 2 cDNA from a silkworm, Bombyx mori[BIOLOGIA,2016-07-13] -  A chemical with proven clinical safety rescues Down-syndrome related phenotypes in through DYRK1A inhibition[DISEASE MODELS & MECHANISMS,2016-07-16] -  Polo kinase phosphorylates Miro to control ER-Mitochondria contact sites and mitochondrial Ca2+ homeostasis in neural stem cell development[ DEVELOPMENTAL CELL,2016-04-18] -  Cloning of the Bombyx mori short neuropeptide F receptor (BsNPF-R) cDNA[생명과학회지,2016-06-01] -  Luteolin-induced apoptosis through activation of endoplasmic reticulum stress sensors in pheochromocytoma cells[MOLECULAR MEDICINE REPORTS,2017-02-07] -  Shedding light on Alzheimer’s β-amyloidosis: photosensitized methylene blue inhibits self-assembly of β-amyloid peptides and disintegrates their aggregates[SCIENTIFIC REPORTS,2017-08-08] -  Zebrafish knockout of Down syndrome gene, DYRK1A, shows social impairments relevant to autism[MOLECULAR AUTISM,2017-09-29] -  Neuropeptide Y mitigates ER stress-induced neuronal cell death by activating the PI3K-XBP1 pathway[EUROPEAN JOURNAL OF CELL BIOLOGY,2018-04-05] -  Larval hemolymph of rhinoceros beetle, Allomyrina dichotoma, enhances insulin secretion through ATF3 gene expression in INS-1 pancreatic β-cells[Zeitschrift fur Naturforschung - Section C Journal of Biosciences,2018-05-22] -  Vascular defects of DYRK1A knockouts are ameliorated by modulating calcium signaling in zebrafish[DISEASE MODELS & MECHANISMS,2019-04-11] -  Prominin-like regulates longevity and glucose metabolism via insulin signaling in Drosophila[JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES,2019-10-01] -  A threonyl-tRNA synthetase-mediated translation initiation machinery[NATURE COMMUNICATIONS,2019-03-22]

특허(최근 5년)

-  CX-4945를 유효성분으로 함유하는 퇴행성 뇌질환 예방 및 치료용 약학적 조성물[2017-02-03] -  아스파라기닐 tRNA 합성효소 (Asparaginyl tRNA synthetase, NRS)의 발현 또는 활성을 억제하는 물질을 포함하는, 암의 예방 또는 치료용 약학적 조성물[2019-06-04] -  피롤로-피리딘 유도체 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 단백질 키나아제 관련 질환의 예방 또는 치료용 약학적 조성물[2018-09-03]