이철주 교수

Cheolju Lee

INFO

  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (생물화학)
  • 연락처02-958-6788
  • 출신전공생물리학
  • 학위박사
  • 최종출신대학서울대학교
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연구분야

생화학, 생물물리학, 단백체학, 질량분석

biochemistry, biophysics, proteomics, mass spectrometry

대표연구실적

-  Both targeted mass spectrometry and flow sorting analysis methods detected the decreased serum apolipoprotein e level in Alzheimer's disease patients. Mol Cell Proteomics. 2014 Feb;13(2):407-19 -  Quantitative analysis of mTRAQ-labeled proteome using full MS scans. J Proteome Res. 2010 Jul 2;9(7):3750-8 -  Identification of S100A8 and S100A9 as serological markers for colorectal cancer. J Proteome Res. 2009 Mar;8(3):1368-79

논문(최근 5년)

-  Identification of ganglioside GM2 activator playing a role in cancer cell migration through proteomic analysis of breast cancer secretomes[Cancer Science,2016-06-01] -  Proteomics-based identification and validation of novel plasma biomarkers phospholipid transfer protein and mannan-binding lectin serine protease-1 in age-related macular degeneration[SCIENTIFIC REPORTS,2016-09-08] -  CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3[NATURE CELL BIOLOGY,2016-03-01] -  Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition[EMBO REPORTS,2016-01-01] -  Common repository of FBS proteins (cRFP) to be added to a asearch database for mass spectrometric analysis of cell secretome[JOURNAL OF PROTEOME RESEARCH,2019-10-04] -  Comparative analysis of differentially secreted proteins in serum-free and serum-containing media by using BONCAT and pulsed SILAC[SCIENTIFIC REPORTS,2019-02-28] -  Fromyl-methionine as an N-degron of a eukaryotic N-end rule pathway[SCIENCE,2018-11-30] -  SEPROGADIC-serum protein-based gastric cancer prediction model for prognosis and selection of proper adjuvant therapy[SCIENTIFIC REPORTS,2018-11-15] -  Quantification of protein markers monitoring the pre-analytical effect[JOURNAL OF MASS SPECTROMETRY,2018-12-01] -  Neutralizing the detrimental effect of an N-hydroxysuccinimide quenching reagent[ANALYTICAL CHEMISTRY,2018-03-06] -  Glioblastoma-secreted soluble CD44 activates tau pathology[EXPERIMENTAL AND MOLECULAR MEDICINE,2018-04-06] -  Comprehensive analysis of human protein N-termini enables assessment[SCIENTIFIC REPORTS,2017-07-26] -  A proteogenomic approach for protein-level evidence of genomic variants[SCIENTIFIC REPORTS,2016-10-13] -  Differentiation of selectively labeled peptides[NANOSCALE,2019-01-31] -  Dedifferentiated Schwann cells secrete proganulin[GLIA,2019-02-01] -  Misfolded polypeptides are selectively recognized[NATURE COMMUNICATIONS,2017-07-07] -  Makes catepillars floppy-like effector[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2019-09-03]

특허(최근 5년)

-  BCHE를 비소세포 폐암 진단용 혈액학적 마커로 사용하는 방법[2017-11-02] -  인터넷·게임 중독 진단용 neuropilin-2 바이오마커 및 이의 검출용 조성물 [2018-01-09]