배광희 교수

Bae, Kwang-Hee

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처042-860-4268
  • 출신전공생물과학과
  • 학위박사
  • 최종출신대학한국과학기술원
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연구분야

비만 및 대사질환, 단백체학, 줄기세포 분화및 제어, 바이오마커 발굴

Obestity and metabolic disorders, Proteomics, Stem cell differentiationa and regulation, Biomarkers

대표연구실적

-  배광희 등, Human zinc fingers as modular building blocks to construction of artificial transcription factors, Nature Biotechnology, 2003.03.15 -  배광희 외, Far upstream element-binding protein, a novel caspase substrate, acts as a cross-talker between apoptosis and c-myc oncogene, Oncogene, 2009.02.16 -  배광희 외, Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity, J. Lipid Res. 2012.09.15

논문(최근 5년)

-  Loss of NDRG2 promotes epithelial-mesenchymal transition of gallblader carcinoma cells through MMP=19-mediated slug expression[ JOURNAL OF HEPATOLOGY,2015-12-01] -  c-Jun regulates adipocyte differentiation via the KLF15-mediated mode[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2016-01-15] -  Profiling analysis of protein tyrosine phosphatases during neuronla differenitation[ NEUROSCIENCE LETTERS,2016-01-26] -  Set7/9, a methyltransferase, regulates the thermogenic program during brown adipocyte differentiation through the modulation of p53 acetylation[ MOLECULAR AND CELLULAR ENDOCRINOLOGY,2016-04-29] -  Methyltransferase and demethylase profiling studies during brown adipocyte differentiation[BMB REPORTS,2016-07-31] -  Structural insight into the critical role of the N-terminal region in the catalytic activity of dual-specificity phosphatase 26[PLOS ONE,2016-09-01] -  High-resolution crystal structure of the PDZ1 domain of human protein tyrosine phosphatase PTP-Bas[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2016-08-18] -  Histone H4 is cleaved by granzyme A during staurosporine-induced cell death in B-lymphoid Raji cells[BMB REPORTS,2016-10-01] -  Graphene oxide induces apoptotic cell death in endothelial cells by activating autophagy via calcium-dependent phophorylation of c-Jun N-terminal kinases[ACTA BIOMATERIALIA,2016-09-15] -  Metabolic adaptation in obesity and type II diabetes: myokines, adipokines and hepatokones[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2016-12-22] -  Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranfin-induced cell death through activation of autophagy in gastric cancer[ONCOTARGET,2016-11-15] -  HDAC11 Inhibits Myoblast Differentiation through repression of MyoD-dependent transcription[Molecules and Cells,2017-09-20] -  DSG2 Is a Functional Cell Surface Marker for Identification and Isolation of human pluripotent stem cells[STEM CELL REPORTS,2018-07-10] -  Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation[NATURE COMMUNICATIONS,2018-08-24] -  Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-Xl[JOURNAL OF BIOLOGICAL CHEMISTRY,2018-11-14] -  Ginkgetin, a biflavone from Ginkgo biloba leaves, prevents adipogenesis through STAT5-mediated PPARg and C/EBPa regulation[PHARMACOLOGICAL RESEARCH,2018-11-22] -  Two distinct cellular pathways leading to endothelial cell cytotoxicity by silica nanoparticle size[JOURNAL OF NANOBIOTECHNOLOGY,2019-02-05] -  The roles of ubiquitination in extrinsic cell death pathways and its implications for therapeutics[BIOCHEMICAL PHARMACOLOGY,2018-11-16] -  Protein Tyrosine Phosphatase, Receptor Type B (PTPRB) Inhibits brown adipocyte differentiation through regulation of VEGF2 phosphorylation[Journal of Microbiology and Biotechnology,2019-04-30] -  Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncogene E7 of human papillomavirus[PLOS BIOLOGY,2019-07-19] -  A reliable approach for assessing size-dependent effects of silica nanoparticles on cellular internalization behavior and cytotoxic mechanisms[INTERNATIONAL JOURNAL OF NANOMEDICINE,2019-09-01] -  The Role of Adipose Tissue Mitochondria: regulation of mitochondrial function for the treatment of metabolic diseases[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2019-10-04]

특허(최근 5년)

-  코플린-1을 이용한 갈색지방세포 분화조절 방법[2016-09-27] -  EpCAM 에 특이적으로 결합하는 핵산 앱타머 및 이의 용도[2016-07-18] -  TCF7L2를 유효성분으로 함유하는 비알콜성 지방간의 예방 및 치료용 약학 조성물[2019-09-03] -  Composition for detecting undifferentiated human pluripotent stem cell, monoclonal antibody 601 and use thereof[2017-09-05] -  콜린성 신경세포의 생산방법 {PROCESS FOR PREPARING CHOLINERGIC NEURONS)[2019-03-19] -  지각추출물 및 콜레우스 포스콜리 추출물을 유효성분으로 함유하는 비만예방 또는 개선용 건강기능식품[2018-10-17]