이창준 교수

Changjoon Justin Lee

INFO

  • 소속캠퍼스기초과학연구원
  • 전공 기초과학
  • 직급캠퍼스대표교수
  • 연락처042-878-9150
  • 출신전공Physiology and Cellular Biophysics
  • 학위박사
  • 최종출신대학Columbia Univ
  • 이메일

연구분야

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Glia-neuron interaction, Receptor and ion channel function, Neurodegenerative diseases, Brain cancer.

대표연구실적

-  Seonmi Jo, Oleg Yarishkin, Yu Jin Hwang,Ye Eun Chun, Mijeong Park,Dong Ho Woo,Jin Young Bae, Taekeun Kim, Jaekwang Lee, Heejung Chun, Hyun Jung Park, Da Yong Lee, Jinpyo Hong, Hye Yun Kim, Soo-Jin Oh, Seung Ju Park, Hyo Lee, Bo-Eun Yoon, YoungSoo Kim, Yong Jeong, Insop Shim, Yong Chul Bae, Jeiwon Cho, Neil W Kowall, Hoon Ryu, Eunmi Hwang, Daesoo Kim, C Justin Lee/GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease/Nature Medicine/29 June 2014 -  TREK-1 and Best1 Channels Mediate Fast and Slow Glutamate Release in Astrocytes upon GPCR Activation/Cell/28 September 2012 -  Soojung Lee, Bo-Eun Yoon, Ken Berglund, Soo-Jin Oh, Hyungju Park, Hee-Sup Shin, George J. Augustine, C. Justin Lee/Channel-Mediated Tonic GABA Release from Glia/Science/3 September 2010

논문(최근 5년)

-  Suppression of 14-3-3γ-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells[Scientific Reports,2016-05-01] -  Ultra-sensitive detection of brain-derived neurotrophic factor (BDNF) in the brain of freely moving mice using an interdigitated microelectrode (IME) biosensor[Scientific Reports,2016-09-01] -  The Ca2+-activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons.[NATURE COMMUNICATIONS,2016-12-19] -  Trifluoperazine, a Well-Known Antipsychotic, Inhibits Glioblastoma Invasion by Binding to Calmodulin and Disinhibiting Calcium Release Channel IP3R.[ MOLECULAR CANCER RESEARCH,2017-01-16] -  Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network.[NATURE COMMUNICATIONS,2017-02-01] -  Bestrophin 1 and retinal disease.[ PROGRESS IN RETINAL AND EYE RESEARCH,2017-01-30] -  Direct interaction with 14-3-3 gamma promotes surface expression of Best1 channel in astrocyte[Molecular Brain,2017-11-01] -  Ultra-sensitive detection of brain-derived neurotrophic factor (BDNF) in the brain of freely moving mice using an interdigitated microelectrode (IME) biosensor[Scientific Reports,2016-09-01] -  The Ca2+-activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons.[NATURE COMMUNICATIONS,2016-12-19] -  Trifluoperazine, a Well-Known Antipsychotic, Inhibits Glioblastoma Invasion by Binding to Calmodulin and Disinhibiting Calcium Release Channel IP3R.[ MOLECULAR CANCER RESEARCH,2017-01-16] -  Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network.[NATURE COMMUNICATIONS,2017-02-01] -  Bestrophin 1 and retinal disease.[ PROGRESS IN RETINAL AND EYE RESEARCH,2017-01-30]

특허(최근 5년)

-  망막의 ONOFF 이극세포 선택적 유전자 발현 방법[2016-02-05] -  소뇌에서의 GABA 방출 조절제[2016-03-25] -  항암활성을 가지는 페노싸이아진 유도체 또는 이의 약학적으로 허용 가능한 염, 이의 제조방법 및 이를 유효성분으로 하는 약학적 조성물[2016-08-03] -  클로라이드 채널 차단제로 유용한 화합물[2017-12-05] -  Aquaporin 4 (AQP4) 유전자의 단일염기다형성 분석을 통한 인지기능 예측[2017-12-06]