강용국 교수

Yong-Kook Kang

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
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연구분야

후성유전학, 발생유전학, 노화

Epigenetics, development, reprogramming. aging

대표연구실적

-  Yong Kook Kang, Deog Bon Koo, Young Hee Choi, Jung Sun Park, An Sik Chung, Kyung Kwang Lee, Yong Mahn Han. "Aberrant methylation of donor genome in cloned bovine embryos" NAT GENET. 28(2) : 173-177. 2001 -  Yong Kook Kang, Jung Sun Park, Deog Bon Koo, Young Hee Choi, Sun-Uk Kim, Kyung Kwang Lee, Yong Mahn Han. "Limited demethylation leaves mosaic-type methylation states in cloned bovine pre-implantation embryos" EMBO J. 21(5) : 1092-1100. 2002 -  Yong Kook Kang, Kyung Kwang Lee, Yong Mahn Han. Reprogramming DNA methylation in the preimplantation stage: peeping with Dolly’s eyes" CURR OPIN CELL BIOL. 15(3) : 290-295. 2003

논문(최근 5년)

-  Transcriptomic Features of Bovine Blastocysts Derived by Somatic Cell Nuclear Transfer.[G3: Genes, Genomes, Genetics,2015-12-01] -  The HIST1 locus escapes reprogramming in cloned bovine embryos.[G3: Genes, Genomes, Genetics,2016-05-02] -  Age-associated chromatin relaxation is enhanced in Huntington’s disease mice.[AGING-US,2017-03-13] -  Characterization of X-chromosome gene expression in bovine blastocysts derived by in vitro fertilization and somatic cell nuclear transfer.[ FRONTIERS IN GENETICS,2017-04-10] -  Simultaneous methylation-level assessment of hundreds of CpG sites by targeted bisulfite PCR sequencing (TBPseq)[FRONTIERS IN GENETICS,2017-07-13] -  Determination of oocyte-manipulation, zygote-manipulation, and genome-reprogramming effects on the transcriptomes of bovine blastocysts.[FRONTIERS IN GENETICS,2018-04-24] -  Age-associated bimodal transcriptional drift reduces intergenic disparities in transcription[AGING-US,2018-04-01] -  Surveillance of Retroelement Expression and Nucleic-Acid Immunity by Histone Methyltransferase SETDB1.[BIOESSAYS,2018-06-13] -  K120R mutation inactivates p53 by creating an aberrant splice site leading to nonsense-mediated mRNA decay[ONCOGENE,2018-10-22] -  Demethylation and derepression of genomic retroelements in the skeletal muscles of aged mice[AGING CELL,2019-08-30]

특허(최근 5년)

-  초기배아 및 줄기세포를 포함한 역분화세포의 양질성 판단방법[2016-02-25]