최수근 교수

Choi Soo Keun

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명공학
    (시스템생명공학)
  • 연락처042-860-4419
  • 출신전공생명과학
  • 학위박사
  • 최종출신대학서울대학교
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연구분야

그람양성균 유전학 및 유전체학

Bacilus Genetics and Genomics

대표연구실적

-  Jeong DE, Park SH, Pan JG, Kim EJ, Choi SK. 2015. Genome engineering using a synthetic gene circuit in Bacillus subtilis. Nucleic Acids Res. 43(6): e42. -  Lim H, Choi SK. 2019. Programmed gRNA removal system for CRISPR-Cas9-mediated multi-round genome editing in Bacillus subtilis. Front. Microbiol. 10: 1140. -  So Y, Park SY, Park EH, Park SH, Kim EJ, Pan JG, Choi SK. 2017. A highly efficient CRISPR-Cas9-mediated large genomic deletion in Bacillus subtilis. Front. Microbiol. 8: 1167.

논문(최근 5년)

-  A Highly efficient CRISPR-Cas9-mediated large genomic deletion in bacillus subtilis[FRONTIERS IN MICROBIOLOGY,2017-07-23] -  Identification of the Biosynthesis Gene Cluster for the Novel Lantibiotic Paenilan from Paenibacillus polymyxa E681 and Characterization of its Product[ JOURNAL OF APPLIED MICROBIOLOGY,2017-09-04] -  Draft Genome Sequences of Four Plant Probiotic Bacillus Strains[Genome Announcements,2016-05-12] -  Genome Sequences of Bacillus thuringiensis Serovar kurstaki Strain BP865 and B. thuringiensis Serovar aizawai Strain HD-133[Genome Announcements,2017-02-02] -  Random knock-in expression system for high yield production of heterologous protein in Bacillus subtilis[ JOURNAL OF BIOTECHNOLOGY,2018-01-20] -  Scarless Genomic Point Mutation to Construct a Bacillus subtilis Strain Displaying Increased Antibiotic Plipastatin Production[Journal of Microbiology and Biotechnology,2018-06-28] -  Genome Sequence of the Probiotic Strain Bacillus velezensis Variant polyfermenticus GF423[Microbiology Resource Announcements,2018-09-13] -  Complete Genome Sequence of Bacillus subtilis Strain WB800N, an Extracellular Protease-Deficient Derivative of Strain 168[Microbiology Resource Announcements,2018-11-08] -  Chronicle of a Soil Bacterium: Paenibacillus polymyxa E681 as a Tiny Guardian of Plant and Human Health[FRONTIERS IN MICROBIOLOGY,2019-03-15] -  Programmed gRNA Removal System for CRISPR-Cas9-Mediated Multi-Round Genome Editing in Bacillus subtilis[FRONTIERS IN MICROBIOLOGY,2019-05-21] -  Expansion of antibacterial spectrum of xanthorrhizol against Gram-negatives in combination with PMBN and food-grade antimicrobials[JOURNAL OF MICROBIOLOGY,2019-05-01] -  Bacillus subtilis spore vaccines displaying protective antigen induce functional antibodies and protective potency[BMC VETERINARY RESEARCH,2020-07-28] -  Regioselective Hydroxylation of Phloretin, a Bioactive Compound from Apples, by Human Cytochrome P450 Enzymes[Pharmaceuticals,2020-10-22]

특허(최근 5년)

-  용균 또는 항균 능력이 개선된 리신 효소 변이체[2016-04-01] -  프로모터 변이체 및 이를 이용한 단백질 생산방법[2016-07-15] -  바실러스 프로모터 변이체 및 이를 이용한 단백질의 제조방법[2016-05-02] -  저장병 방제용 균주 및 이를 이용한 저장병 방제 방법[2017-07-13] -  degU의 변이된 단백질을 포함하는 바실러스 속(Bacillus sp.) 균주 및 이를 포함하는 항균 조성물[2017-09-29] -  단백질 발현 미세 조절방법[2019-02-08]

연구과제 수행 실적

항생제-내성 슈퍼박테리아 제어 연구 해독제용 다중발현벡터 연구