임혜원 교수

Rhim, Hyewhon

INFO

  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (생체신경과학)
  • 연락처02-958-5923
  • 출신전공신경생리학
  • 학위박사
  • 최종출신대학Univ Chicago
  • 이메일

연구분야

신경생물학 ; 생리약학 ; 의과학

Neurobiology ; Physiological Pharmacy ; Medical Sciences

대표연구실적

-  Lee, M. S., Kim, Y. H., Park, W. S., Park, O. K., Kwon, S., Hong, K., H. Rhim, I. Shim, K. Morita, D. L .Wong, P. D. Patel, D. M. Lyons, A. F. Schatzberg & Her. S./ Temporal variability of glucocorticoid receptor activity is functionally important for the therapeutic action of fluoxetine in the hippocampus./ Molecular psychiatry/2014.09 -  Kim J, Kim Y, Tae J, Yeom M, Moon B, Huang XP, Roth BL, Lee K, Rhim H, Choo IH, Chong Y, Keum G, Nam G, Choo H/ Aryl Biphenyl-3-ylmethylpiperazines as 5-HT7 Receptor Antagonists./ ChemMedChem./2013. 11 -  Kim, S. H., Kim, D. H., Lee, K. H., Im, S. K., Hur, E. M., Chung, K. C., & Rhim, H./ Direct Interaction and functional coupling between human 5-HT6 receptor and the light chain 1 subunit of the microtubule-associated protein 1B (MAP1B-LC1)./ PloS one /2014. 02

논문(최근 5년)

-  Memory and synaptic plasticity are impaired by dysregulated hippocampal O-GlcNAcylation[SCIENTIFIC REPORTS,2017-04-03] -  Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway.[MOLECULAR NEUROBIOLOGY,2019-01-01] -  Functional significance of O-GlcNAc modification in regulating neuronal properties.[PHARMACOLOGICAL RESEARCH,2018-03-01] -  Acutely elevated O-GlcNAcylation suppresses hippocampal activity by modulating both intrinsic and synaptic excitability factors.[SCIENTIFIC REPORTS,2019-05-01]

특허(최근 5년)

-  하나의 탐침을 사용하여 전기생리적으로 확인된 뇌 부위에 정확히 약물을 주입하는 방법[2018-01-19] -  유전자 재조합 표적 서열 검출용 키트 및 그를 이용하여 표적 서열을 검출하는 방법[2017-08-10]