김상헌 교수

Kim Sang Heon

INFO

  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (의공학)
  • 연락처02-958-5344
  • 출신전공생명공학
  • 학위박사
  • 최종출신대학Tokyo Institute of Technology
  • 이메일

연구분야

재생의학, 조직공학, 줄기세포치료제, 재생기전연구, 3D 생체모델

Regenerative medicine, tissue engineering, stem cell therapy, tissue regeneration mechanism, 3D tissue model for drug screening

대표연구실적

-  Thanavel Rajangam, K-S Moon, D. Kim, J. Kang, S. Lee, S. J. Oh, S-H. Kim, Therapeutic effect of a xeno-free cultured three-dimensional stem cell mass in a hind limb ischemia mouse model, Tissue Eng., 25 (2019) -  2. Jungmi Kang, Min Han, In Su Park, Soo Hyun Kim, Youngmee Jung, and Sang-Heon Kim, Adhesion and differentiation of adipose-derived stem cells on a substrate wit immobilized fibroblast growth factor, Acta Biomat., 2012 -  3. In Su Park, Min Han, Jong Won Rhie, Soo Hun Kim, Youngmee Jung, Ick Hwan Kim, Sang-Heon Kim, “The correlation between human adipose-derived stem cells differentiation and cell adhesion mechanism”, Biomaterials, 30;6835-6843, 2009

논문(최근 5년)

-  Biomimetic 3D Clusters Using Human Adipose Derived Mesenchymal Stem Cells and Breast Cancer Cells: A Study on Migration and Invasion of Breast Cancer Cells[MOLECULAR PHARMACEUTICS,2016-05-10] -  Approximating bone ECM: Crosslinking directs individual and coupled osteoblast/osteoclast behavior[ BIOMATERIALS,2016-10-01] -  Elasticity Modulation of Fibroblast-Derived Matrix for Endothelial Cell Vascular Morphogenesis and Mesenchymal Stem Cell Differentiation[ TISSUE ENGINEERING PART A,2016-02-24] -  3D human adipose-derived stem cell clusters as a model for in vitro fibrosis[ TISSUE ENGINEERING PART C-METHODS,2016-06-23] -  Combinatorial therapy with three-dimensionally cultured adipose-derived stromal cells and self-assembling peptides to enhance angiogenesis and preserve cardiac function in infarcted hearts[JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE,2016-03-07] -  Novel platform of cardiomyocyte culture and coculture via fibroblast-derived matrix-coupled aligned electrospun nanofiber[ACS Applied Materials & Interfaces,2016-12-12] -  Human lung fibroblast-derived matrix facilitates vascularmorphogenesis in 3D environment and enhances skin wound healing[Acta Biomaterialia,2017-05-01] -  Simple in Vivo Gene Editing via Direct Self-Assembly of Cas9 Ribonucleoprotein Complexes for Cancer Treatment[ACS Nano,2018-07-20] -  Synergistic Therapeutic Effect of Three-Dimensional Stem Cell Clusters and Angiopoietin-1 on Promoting Vascular Regeneration in Ischemic Region[Tissue Engineering - Part A,2018-04-01] -  Cytotoxic and anticancer properties of new ruthenium polypyridyl complexes with different lipophilicities[Journal of Inorganic Biochemistry,2018-03-01] -  Modelling cardiac fibrosis using three- dimensional cardiac microtissues derived from human embryonic stem cells[JOURNAL OF BIOLOGICAL ENGINEERING,2019-02-13] -  Effect of chain flexibility on cell adhesion: Semi-flexible model based analysis of cell adhesion to hydrogels[Scientific Reports,2019-02-21] -  Boiling Histotripsy-induced Partial Mechanical Ablation Modulates Tumour Microenvironment by Promoting Immunogenic Cell Death of Cancers[Scientific Reports,2019-06-21] -  The three dimensional cues-integrated-biomaterial potentiates differentiation of human mesenchymal stem cells[Carbohydrate Polymers,2018-12-01] -  Therapeutic Effect of a Xeno-Free Three-Dimensional Stem Cell Mass in a Hind Limb Ischemia Model[Tissue Engineering - Part A,2019-04-17] -  MBP-FGF2-Immobilized Matrix Maintains Self-Renewal and Myogenic Differentiation Potential of Skeletal Muscle Stem Cells[International Journal of Stem Cells,2019-02-28]

특허(최근 5년)

-  Method for differentiation of stem cells into vascular cells and the induction of angiogenesis using the sam[2017-05-09] -  가교화된 PVA-ECM 복합체를 제조하는 방법 및 그에 의하여 제조된 PVA-ECM 복합체[2017-03-03] -  세포외기질이 코팅된 마이크로섬유 지자체 및 그 제조방법[2017-05-12] -  3차원 세포집합체 및 안지오포이에틴을 포함하는 허혈성 질환 예방 및 치료용 약학적 조성물[2017-06-05] -  인 비트로 섬유증 모델,그의 제조방법 및 용도[2017-06-21] -  인 비트로 3차원 세포 배양 모델, 이의 제조 방법 및 이를 이용한 스크리닝 방법[2018-11-13] -  세포 부착 제어를 통한 중간엽줄기세포를 분류하는 방법 및 그를 위한 단백질이 코팅된 배양 용기 [2018-03-13] -  생체적합성 조직을 제조하는데 사용하기 위한 조성물, 그를 제조하는 방법 및 상기 조성물을 이용한 혈관 형성이 필요한 질병을 치료하는 방법[2019-04-19]