정해용 교수

Haiyoung Jung

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처042-860-4218
  • 출신전공생화학 및 분자생물학
  • 학위박사
  • 최종출신대학충북대학교
  • 이메일

연구분야

면역학 (조혈줄기세포, 자연살해세포)

Immunology (Hematopoietic stem cell, NK cell)

대표연구실적

-  Haiyoung Jung, Dong Oh Kim, Jae-Eun Byun, Won Sam Kim, Mi Jeong Kim, Hae Young Song, Young Kwan Kim, Du-Kyeong Kang, Young-Jun Park, Tae-Don Kim, Suk Ran Yoon, Hee Gu Lee, Eun-Ji Choi, Sang-Hyun Min & Inpyo Choi /Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity/Nature Communications/2016.12.08 -  Hangsak Huy, Hae Young Song, Mi Jeong Kim, Won Sam Kim, Dong Oh Kim, Jae­Eun Byun, Jungwoon Lee, Young­Jun Park, Tae­Don Kim, Suk Ran Yoon, Eun­Ji Choi, Chul­Ho Lee, Ji­Yoon Noh, Haiyoung Jung* and Inpyo Choi*/TXNIP regulates AKT-mediated cellular senescence by direct interaction under glucose-mediated metabolic stress/Aging Cell/2018.08.31 -  Mi Jeong Kim, Won Sam Kim, Jae-Eun Byun, Jung Ha Choi, Suk Ran Yoon*, Inpyo Choi* and Haiyoung Jung* /Inhibition of osteoclastogenesis by thioredoxin-interacting protein-derived peptide (TN13)/Journal of Clinical Medicine/2019.03.29

논문(최근 5년)

-  Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer[Oncotarget,2016-11-15] -  Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity[NATURE COMMUNICATIONS,2016-12-08] -  Identification of proteins suppressing the functions of oncogenic phosphatase of regenerating liver 1 and 3[EXPERIMENTAL AND THERAPEUTIC MEDICINE,2016-08-11] -  Suppressor of cytokine signaling 2 negatively regulates NK cell differentiation by inhibiting JAK2 activity[SCIENTIFIC REPORTS,2017-04-06] -  MicroRNA-150 modulates intracellular Ca 2+ levels in naive CD8+ T cells by targeting TMEM20[SCIENTIFIC REPORTS,2017-06-01] -  Ginsenoside Rg3 ameliorated HFD-induced hepatic steatosis through downregulation of STAT5-PPARγ[JOURNAL OF ENDOCRINOLOGY,2017-09-26] -  Role of protein kinases and their inhibitors in radiation response of tumor cells[CURRENT PHARMACEUTICAL DESIGN,2017-05-30] -  Macrophage migration inhibitory factor interacts with thioredoxin-interacting protein and induces NF-κB activity[CELLULAR SIGNALLING,2017-03-18] -  Pharmacological regulation of oxidative stress in stem cells[OXIDATIVE MEDICINE AND CELLULAR LONGEVITY,2018-09-30] -  MicroRNA-150 controls differentiation of intraepithelial lymphocytes through TGF-β receptor II regulation[JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY,2017-08-07] -  Prostaglandin E2 secreted by thyroid cancer cells contributes to immune escape through the suppression of natural killer (NK) cell cytotoxicity and NK cell differentiation[FRONTIERS IN IMMUNOLOGY,2018-08-09] -  Thioredoxin-interacting protein-derived peptide (TN13) inhibits LPS-induced inflammation by inhibiting p38 MAPK signaling[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2018-11-16] -  TLR4/NF-κB axis induces fludarabine resistance by suppressing TXNIP expression in acute myeloid leukemia cells[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2018-10-15] -  TXNIP regulates AKT-mediated cellular senescence by direct interaction under glucose-mediated metabolic stress[AGING CELL,2018-08-31] -  Protein kinases and their inhibitors in pluripotent stem cell fate regulation[STEM CELLS INTERNATIONAL,2019-07-24] -  A negative feedback loop between XBP1 and Fbw7 regulates cancer development[ONCOGENESIS,2019-01-28] -  Indoleamine-2,3-dioxygenase in thyroid cancer cells suppresses natural killer cell function by inhibiting NKG2D and NKp46 expression via STAT signaling pathways[JOURNAL OF CLINICAL MEDICINE,2019-06-12] -  Inhibition of osteoclastogenesis by thioredoxin-interacting protein-derived peptide (TN13)[JOURNAL OF CLINICAL MEDICINE,2019-03-29] -  Causes and mechanisms of hematopoietic stem cell aging[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2019-03-13] -  Thioredoxin-interacting protein promotes phagosomal acidification upon exposure to Escherichia coli through inflammasome-mediated caspase-1 activation in macrophages[FRONTIERS IN IMMUNOLOGY,2019-11-12] -  Anti-inflammatory activities of astringent persimmons (Diospyros kaki Thunb.) stalks of various cultivar types based on the stages of maturity in the Gyeongnam province[BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE,2019-08-28] -  Toll-like receptors in natural killer cells and their application for immunotherapy[JOURNAL OF IMMUNOLOGY RESEARCH,2020-01-04]

특허(최근 5년)

-  티오레독신-결합 단백질을 유효성분으로 포함하는 약학적 조성물 및 이의 용도[2016-02-24] -  티오레독신 결합단백질 유래 펩타이드 또는 이를 암호화하는 폴리뉴클레오타이드를 유효성분으로 함유하는 노화줄기세포의 역노화용 조성물 및 이의 용도[2019-06-03]