빅데이터 인공지능을 이용한 신약개발 후보물질 발굴, 단백질 구조 모델링, 분자동력학 시뮬레이션, 가상 스크리닝
Big data driven based on AI drug candidate discovery, Protein Structure modeling, Molecular dynamics simulation, Protein-Ligand docking
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- Effects of cadmium on the cuttlefish Sepia pharaonis arginine kinase: unfolding kinetics integrated with computational simulations[ JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS,2016-01-01]
- Discovery of polymethoxyflavones from black ginger (Kaempferia parviflora) as potential β-secretase (BACE1) inhibitors[ JOURNAL OF FUNCTIONAL FOODS,2015-12-02]
- Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis[ MOLECULAR NEURODEGENERATION,2016-01-01]
- Designing an Antibody-based Chaperoning System through Programming the Binding and Release of Folding Intermediate[ ACS CHEMICAL BIOLOGY,2016-06-01]
- Integration of Inhibition Kinetics and Molecular Dynamics Simulations: A Urea-Mediated Folding Study on Acetaldehyde Dehydrogenase 1[ APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY,2016-05-01]
- Effect of Cadmium Ion on alpha-glucosidase: An inhibition kinetics and molecular dynamics simulation integration study[ PROTEIN JOURNAL,2016-05-05]
- A computational integrating kinetic study on the flexible active site of human acetaldehyde dehydrogenase 1[ PROCESS BIOCHEMISTRY,2016-03-15]
- Anti-obesity effects of spiramycin in vitro and in vivo[ PLOS ONE,2016-07-11]
- Effect of Cd2+ on tyrosinase: integration of inhibition kinetics with computational simulation[ INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2016-09-11]
- Identification of biochanin A as a potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitor[ NUTRIENTS,2016-10-14]
- Clinical Relevance and Molecular Phenotypes in Gastric Cancer, of TP53 Mutations and Gene Expressions, in Combination With Other Gene Mutations[ SCIENTIFIC REPORTS,2016-10-06]
- Systematic approach in identifying RHOA as a Potential Asian Gastric Cancer Biomarker Therapeutic Target[ ONCOTARGET,2016-10-28]