판철호 교수

Pan, Cheol-Ho

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  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (생물화학)
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  • 출신전공농화학
  • 학위박사
  • 최종출신대학서울대학교
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연구분야

천연물생이용성, 단백질-천연물 상호작용, 단백질 화학

bioavailability of natural product, protein-natural product interaction, protein chemistry

대표연구실적

-  Lee H. J., Cha K. H., Kim C. Y., Nho C. W., and Pan C. H. (2014) Bioavailability of Hydroxycinnamic Acids from Crepidiastrum denticulatum Using Simulated Digestion and Caco-2 Intestinal Cells. J. Agric. Food Chem., 62 : 5290-5295. -  Jung W.-S., Singh R. K., Lee J. K., and Pan C. H. (2013) Crystal Structure and Substrate Specificity of D-Galactose-6-Phosphate Isomerase Complexed with Substrates. PLoS ONE, 8 : e72902. -  Kang K., Song D. G., Lee E. H., Lee K. M., Park Y. G., Jung S. H., Pan C. H.*, and Nho C. W.* (2014) Secretome Profiling Reveals the Signaling Molecules of Apoptotic HCT116 Cells Induced by the Dietary Polyacetylene Gymnasterkoreayne B. J. Agric. Food Chem., 62 : 2353-2363. * Equal contribution

논문(최근 5년)

-  Development, Quantification, Method Validation, and Stability Study of a Novel Fucoxanthin-Fortified Milk[Journal of agricultural and food chemistry,2016-07-25] -  The Protective Effect of Antioxidant Enriched Fractions from Colored Potatoes Against Hepatotoxic Oxidative Stress in Cultured Hepatocytes and Mice[ JOURNAL OF FOOD BIOCHEMISTRY,2016-08-08] -  Expression, phosphorylation, localization, and microtubule binding of tau in colorectal cell lines[APPLIED BIOLOGICAL CHEMISTRY,2016-12-30] -  Cloning of a novel endogenous promoter for foreign gene expression in Phaeodactylum tricornutum[APPLIED BIOLOGICAL CHEMISTRY,2016-11-18] -  Fucoxanthin Suppresses Lipid Accumulation and ROS Production During Differentiation in 3T3-L1 Adipocytes[ PHYTOTHERAPY RESEARCH,2016-07-13] -  Mathematical models of pretreatment processes to utilize purple-fleshed potato (Solanum tuberosum L.) peels for anthocyanin extraction[FOOD SCIENCE AND BIOTECHNOLOGY,2016-10-31] -  Preparation of Fucoxanthin-Loaded Nanoparticles Composed of Casein and Chitosan with Improved Fucoxanthin Bioavailability[ JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2016-11-23] -  A highly efficient sorbitol dehydrogenase from Gluconobacter oxydans G624 and improvement of its stability through immobilization[SCIENTIFIC REPORTS,2016-09-16] -  Evaluation of the anti-obesity effect of the microalga Phaeodactylum tricornutum[APPLIED BIOLOGICAL CHEMISTRY,2016-02-01] -  Identification of Antioxidants in Lamiaceae Vegetables by HPLC-ABTS and HPLC-MS[Chiang Mai University Journal of Natural Sciences,2016-04-29] -  Ranitidine-induced anaphylaxis: clinical features, cross-reactivity, and skin testing[ CLINICAL AND EXPERIMENTAL ALLERGY,2016-04-29] -  High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells[Biotechnology letters,2017-11-21] -  Determination of Principal Components for Characterizing the Drying of Sea Cucumbers (Stichopus japonicus Selenka) Using Far Infrared Radiation Drying and Hot Air Drying[Journal of Aquatic Food Product Technology,2016-06-27] -  Effects of fermented milk treatment on microbial population and metabolomic outcomes in a three-stage semi-continuous culture system[FOOD CHEMISTRY,2018-04-23] -  AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo[JOURNAL OF ETHNOPHARMACOLOGY,2017-03-09] -  Identification and characterisation of the novel endogenous promoter HASP1 and its signal peptide from Phaeodactylum tricornutum[SCIENTIFIC REPORTS,2019-07-01] -  Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells[JOVE-JOURNAL OF VISUALIZED EXPERIMENTS,2017-09-01] -  Comparison of static and dynamic in vitro digestion models to estimate the bioaccessibility of lutein in lutein-rich foods[APPLIED BIOLOGICAL CHEMISTRY,2018-06-12] -  3,3'-Diindolylmethane improves intestinal permeability dysfunction in cultured human intestinal cells and the model animal Caenorhabditis elegans[JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2019-07-28] -  Machine learning-based chemical binding similarity using evolutionary relationships of target genes[NUCLEIC ACIDS RESEARCH,2019-08-01] -  Effects of temperature, light, and pH on the stability of fucoxanthin in an oil-in-water emulsion[FOOD CHEMISTRY,2019-04-01] -  Fucoxanthin bioavailability from fucoxanthin-fortified milk: In vivo and in vitro study[FOOD CHEMISTRY,2018-03-13] -  Glutamyl-prolyl-tRNA synthetase induces fibrotic extracellular matrix via both transcriptional and translational mechanisms[FASEB JOURNAL,2019-03-01] -  Glutamyl-Prolyl-tRNA Synthetase Regulates Epithelial Expression of Mesenchymal Markers and Extracellular Matrix Proteins: Implications for Idiopathic Pulmonary Fibrosis[FRONTIERS IN PHARMACOLOGY,2018-11-01] -  TM4SF5 promotes metastatic behavior of cells in 3D extracellular matrix gels by reducing dependency on environmental cues[Oncotarget,2017-05-07] -  Anti-Obesity Effect of Standardized Extract of Microalga Phaeodactylum tricornutum Containing Fucoxanthin[MARINE DRUGS,2019-05-01] -  Small black bean (Rhynchosia volubilis) extract ameliorates gut microbial and metabolic perturbation in ovariectomized mice[JOURNAL OF FUNCTIONAL FOODS,2019-09-01] -  Antiprotozoal activity of major constituents from the bioactive fraction of Verbesina encelioides[NATURAL PRODUCT RESEARCH,2016-05-01] -  Data on the anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin in mice[Data in Brief,2017-05-17]

특허(최근 5년)

-  유색감자를 포함하는 면의 제조방법[2016-06-02] -  고속 액체 크로마토그래피 장치 및 이를 이용한 물질 스크리닝 방법[2018-01-18] -  부처손 알코올 추출물을 유효성분으로 포함하는 화학요법제와의 병용투여를 위한 항암 조성물[2017-11-23] -  푸코잔틴을 포함하는 디하이드로테스토스테론 과다생성에 의해 유발되는 질병 예방 및 치료용 조성물[2018-01-09] -  LB 배지를 포함하는 미세조류 배양용 배지 조성물[2017-11-10] -  더덕 추출물을 함유하는 장 건강 개선용 조성물[2018-02-01] -  미세조류의 배양 농도 또는 푸코잔틴 및 클로로필의 생산을 증대시키는 미생물 스타피아 또는 스타피아 배양물[2017-11-10] -  락토바실러스 카세이 균주를 포함하는 미세먼지 독성에 대한 세포 및 조직 보호용 조성물[2018-10-22] -  섬바디 추출물을 포함하는 동맥경화증의 예방 또는 치료용 조성물[2019-07-26] -  남성 호르몬 생성촉진용 조성물[2019-03-05] -  베타 사이클로덱스트린 기반의 푸코잔틴 미세분말 및 이의 제조방법[2018-07-03] -  키토산으로 코팅된 카세인 기반의 푸코잔틴 미세분말 및 이의 제조방법[2018-07-02] -  홍국 추출물을 포함하는 장 건강 개선용 조성물[2018-04-13] -  실리마린을 포함하는 장 건강 개선용 조성물[2018-10-11] -  인간상피세포 성장인자 또는 피부침투성 인간상피세포 성장인자 발현용 벡터 및 상기 벡터로 형질전환된 미세조류[2019-08-19] -  Boc 화합물을 이용하여 아민기를 포함하는 화합물을 분석하는 방법[2019-07-04] -  생두 커피콩 및 아임계수를 이용하여 커피를 제조하는 방법[2018-06-01] -  카세인 기반의 푸코잔틴 미세분말 및 이의 제조방법[2018-07-03] -  유청 단백질 기반의 푸코잔틴 미세분말 및 이의 제조방법[2018-07-03]