이재욱 교수

Jae Wook Lee

INFO

  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (생물화학)
  • 연락처033-650-3514
  • 출신전공생유기화학
  • 학위박사
  • 최종출신대학New York Univ
  • 이메일

연구분야

천연물 초고속활성검색, 의약화학

natural product HTS/HCS, medicinal chemistry

대표연구실적

-  Identification of small molecule activators of cryptochrome T. Hirota, J. W. Lee et. al Science 2012, 337, 1094 -  A Small Molecule Modulates Circadian Rhythms through Phosphorylation of the Period Protein Lee, J. W.; Hirota, T. Angew. Chem. Int. Ed. 2011, 50,10608-10611. -  Stepwise Chemically Induced Cardiomyocyte Specification of Human Embryonic Stem Cells. Gonzalez, R.; Lee, J. W Angew. Chem. Int. Ed. 2011, 50, 11181-11185

논문(최근 5년)

-  Synthesis of pyrazine via chemoselective reduction of β-keto-α-oximino ester using baker’s yeast[Journal of molecular catalysis. B, Enzymatic,2016-01-01] -  Gambogic acid induces apoptotic cell death in T98G glioma cells[Bioorganic & medicinal chemistry letters,2016-02-01] -  Discovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic β-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress[Journal of medicinal chemistry,2016-08-01] -  Gambogic Acid-induced Autophagy and the MAPK Pathway in T98GGlioblastoma Cells[Bulletin of the Korean Chemical Society,2017-10-01] -  Chemical characterization of cytotoxic indole acetic acid derivative from mulberry fruit (Morus alba L.) against human cervical cancer[Bioorganic chemistry,2018-02-01]

특허(최근 5년)

-  구글스테론 유도체의 제조방법 및 그를 포함하는 항암제 조성물 [2016-07-01] -  등나무 추출물 및 분획을 함유하는 피부 미백 조성물[2018-01-12] -  도시 옥상 식물 재배용 에너지 절약형 지속가능한 저장장치 및 연계된 관수장치 개발 [2018-01-02] -  구굴스테론 유도체를 포함하는 신독성 감소용 조성물[2018-01-19]