김원곤 교수

Won-Kon Kim

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명과학
    (기능유전체학)
  • 연락처042-860-4265
  • 출신전공줄기세포학
  • 학위박사
  • 최종출신대학고려대학교
  • 이메일

연구분야

비만, 지방세포 분화, 대사성 질환, 줄기세포 분화, 프로테오믹스,

Obesity, Adipocyte Differentiation, Metabolic Disease, Stem Cell Differentiation, Proteomics

대표연구실적

-  Kim WK et al./Myostatin inhibits brown adipocyte differentiation via regulation of Smad3-mediated β-catenin stabilization/. Int. J. Biochem. Cell Biol./2012 -  Kim WK et al.,/RPTPμ tyrosine phosphatase promotes adipogenic differentiation via modulation of p120 catenin phosphorylation/Mol. Biol. Cell/2011 -  Kim et al.,/Regulation of adipogenic differentiation by LAR tyrosine phosphatase in human mesenchymal stem cells and 3T3-L1 preadipocytes/J. Cell Sci./2009

논문(최근 5년)

-  c-Jun regulates adipocyte differentiation via the KLF15-mediated mode[ BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2015-12-13] -  Profiling analysis of protein tyrosine phosphatases during neuronal differentiation[ NEUROSCIENCE LETTERS,2015-12-15] -  High-performance dendritic contrast agents for X-ray computed tomography imaging using potent tetraiodobenzene derivatives[ JOURNAL OF CONTROLLED RELEASE,2016-01-23] -  Set7/9, a methyltransferase, regulates the thermogenic program during brown adipocyte differentiation through the modulation of p53 acetylation[ MOLECULAR AND CELLULAR ENDOCRINOLOGY,2016-04-29] -  Methyltransferase ans demethylase profiling studies during brown adipocyte differentiation[BMB REPORTS,2016-05-02] -  Metabolic adaptation in obesity and type II diabetes: myokines, adipokines and hepatokines[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2016-12-22] -  Proteomics 분석기반 갈색지방 활성화 및 백색지방의 갈색지방화(browning)조절 연구[한국식품과학회지,2017-03-20] -  Phosphorylation of p53 at threonine 155 is required for Jab-1 mediated nuclear export of p53[BMB REPORTS,2017-05-25] -  HDAC11 inhibits myoblast differentiation through repression of MyoD-dependent transcription[MOLECULES AND CELLS,2017-09-20] -  Ginkgetin, a biflavone from Ginkgo biloba leaves, prevents adipogenesis through STAT5-mediated PPARγ and C/EBPα regulation[PHARMACOLOGICAL RESEARCH,2018-11-22] -  Two distinct cellular pathways leading to endothelial cell cytotoxicity by silica nanoparticle size[JOURNAL OF NANOBIOTECHNOLOGY,2019-02-05] -  Protein tyrosine phosphatase, receptor type B (PTPRB) inhibits brown adipocyte differentiation through regulation of VEGFR2 phosphorylation[JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,2019-02-20] -  A reliable approach for assessing size-dependent effects of silica nanoparticles on cellular internalization behavior and cytotoxic mechanisms[INTERNATIONAL JOURNAL OF NANOMEDICINE,2019-09-10] -  Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus[PLOS BIOLOGY,2019-07-19] -  The Role of Adipose Tissue Mitochondria: Regulation of Mitochondrial Function for the Treatment of Metabolic Diseases[INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2019-10-04] -  Adipokine & NAFLD[JOURNAL OF CLINICAL MEDICINE,2019-10-31] -  IDH1-dependent α-KG regulates brown adipocyte differentiation by[METABOLISM-CLINICAL AND EXPERIMENTAL,2020-01-22] -  Roles of protein histidine phosphatase 1 (PHPT1) in brown adipocyte differentiation[Journal of Microbiology and Biotechnology,2020-01-31] -  Adipokine & NAFLD[JOURNAL OF CLINICAL MEDICINE,2019-10-31] -  IDH1-dependent α-KG regulates brown adipocyte differentiation by[METABOLISM-CLINICAL AND EXPERIMENTAL,2020-01-22] -  Roles of protein histidine phosphatase 1 (PHPT1) in brown adipocyte differentiation[Journal of Microbiology and Biotechnology,2020-01-31]

특허(최근 5년)

-  성상세포의 생산방법 [2017-10-30] -  EpCAM에 특이적으로 결합하는 핵산 앱타머 및 이의 용도 [2016-07-18] -  신규한 신경세포 마커 및 이의 용도 [2016-09-28] -  코플린-1을 이용한 갈색 지방세포 분화 조절 방법 [2016-09-27] -  콜린성 신경세포의 생산방법 [2017-09-08] -  지각 추출물 및 콜레우스 포스콜리 추출물을 유효성분으로 함유하는 비만 예방 또는 개선용 건강기능식품 [2018-10-17] -  Process for preparing cholinergic neurons[2019-03-19] -  TCF7L2를 유효성분으로 함유하는 비알코올성 지방간의 예방 또는 치료용 약학 조성물 [2019-09-03]