이대희 교수

Lee Daehee

INFO

  • 소속캠퍼스한국생명공학연구원 스쿨
  • 전공 생명공학
    (시스템생명공학)
  • 연락처042-879-8225
  • 출신전공생물공학
  • 학위박사
  • 최종출신대학서울대학교
  • 이메일
개인홈페이지

연구분야

합성생물학 및 대사공학

Synthetic Biology & Metabolic Engineering

대표연구실적

-  Seong Keun Kim, P K Yoon, Soo Jung Kim, Seung Gyun Woo, Eugene Rha, Hyewon Lee, Soo Jin Yeom, Haseong Kim, Dae-Hee Lee, Seung Goo Lee (2020) "CRISPR interference-mediated gene regulation in Pseudomonas putida KT2440" MICROB BIOTECHNOL. 13(1) : 210-221. -  Soo Jung Kim, Seong Keun Kim, Wonjae Seong, Seung Gyun Woo, Hyewon Lee, Soo Jin Yeom, Haseong Kim, Dae-Hee Lee, Seung Goo Lee (2019) "Enhanced (-)-alpha-bisabolol productivity by efficient conversion of mevalonate in Escherichia coli" CATALYSTS. 9(0) : 432-432. -  Seong Keun Kim, S H Kim, B Subhadra, Seung Gyun Woo, Eugene Rha, S W Kim, Haseong Kim, Dae-Hee Lee, Seung Goo Lee (2018) "A genetically encoded biosensor for monitoring isoprene production in engineered Escherichia coli" ACS SYNTH BIOL. 7(0) : 2379-2390.

논문(최근 5년)

-  Fumarate-mediated persistence of Escherichia coli against antibiotics[ANTIMICROBIAL AGENTS AND CHEMOTHERAPY,2016-04-01] -  A cell-cell communication-based screening system for novel microbes with target enzyme activities?[ACS SYNTHETIC BIOLOGY,2016-07-25] -  CRISPR interference-guided balancing of a biosynthetic mevalonate pathway increases terpenoid production[METABOLIC ENGINEERING,2016-11-01] -  Fermentative production and direct extraction of (-)-alpha-bisabolol in?metabolically engineered?Escherichia coli[MICROBIAL CELL FACTORIES,2016-11-08] -  Long-term stable and tightly controlled expression of recombinant proteins in antibiotics-free conditions[PLOS ONE,2016-12-01] -  Production of D-ribose by metabolically engineered?Escherichia?coli??[PROCESS BIOCHEMISTRY,2017-01-02] -  Leucine zipper-mediated targeting of multi-enzyme cascade reactions to inclusion bodies in Escherichia coli for enhanced production of 1-butanol[METABOLIC ENGINEERING,2017-03-01] -  Controlled aggregation and increased stability of beta-glucuronidase by cellulose binding domain fusion[PLOS ONE,2017-01-18] -  Efficient transcriptional gene repression by type V-A CRISPR-Cpf1 from Eubacterium eligens[ACS SYNTHETIC BIOLOGY,2017-04-04] -  Tunable control of an Escherichia coli expression system for the overproduction of membrane proteins by titrated expression of a mutant lac repressor[ACS SYNTHETIC BIOLOGY,2017-05-19] -  Enhanced production of xylitol from xylose by expression of Bacillus?subtilis arabinose:H+?supporter and Scheffersomyces stipitis xylose reductase in recombinant Saccharomyces cerevisiae?[ENZYME AND MICROBIAL TECHNOLOGY,2017-12-01] -  CRISPR interference-guided multiplex repression of endogenous competing pathway genes for redirecting metabolic flux in Escherichia coli [MICROBIAL CELL FACTORIES,2017-11-03] -  Evolution of enzymes with new specificity by high-throughput screening using DmpR-based genetic circuits and multiple flow cytometry rounds[SCIENTIFIC REPORTS,2018-02-08] -  Development of a novel cellulase biosensor that detects crystalline cellulose hydrolysis using a transcriptional regulator[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2018-01-01] -  Tabrizicola fusiformis sp. nov., isolated from an industrial wastewater treatment plant [INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY,2018-04-06]

특허(최근 5년)

-  재설계 유전자회로를 이용한 아미노카프론산의 감지 및 정량 방법[2017-08-31] -  신규 카프로락탐 전환 효소 및 이를 이용한 카프로락탐 생산 방법[2017-03-07] -  단백질 융합 디스플레이 기술을 이용한 물질 간 상호작용 고속분석 방법[2017-04-28] -  재설계 유전자회로를 이용한 카프로락탐의 감지 및 정량 방법[2017-03-31] -  재설계 유전자회로를 이용한 섬유소분해효소 활성의 신규 탐색 및 정량방법[2016-07-07]