양유수 교수

Yoosoo Yang

INFO

  • 소속캠퍼스한국과학기술연구원 스쿨
  • 전공 바이오-메디컬 융합
    (생물화학)
  • 연락처029586655
  • 출신전공생명공학(생화학)
  • 학위박사
  • 최종출신대학성균관대학교 자연과학캠퍼스
  • 이메일

연구분야

엑소좀,막융합, 신경전달물질 방출, 스네어

exosome,membrane fusion, neuroexocytosis, SNARE

대표연구실적

-  Yeonsun Hong, Gi-Hoon Nam, Eunee Koh, Sangmin Jeon, Gi Beom Kim, Cherlhyun Jeong, Dong-Hwee Kim, Yoosoo Yang*; In-San Kim / Exosome as a vehicle for delivery of membrane protein therapeutics, PH20, for enhanced tumor penetration and antitumor efficacy/ Adv Funct Mater/201804 -  Yoosoo Yang1,*, Yeonsun Hong, Gi-Hoon Nam, Jin Hwa Chung, Eunee Koh, and In-San Kim* /Virus-mimetic fusogenic exosomes for direct delivery of integral membrane proteins to target cell membranes/ Adv Mater /201704 -  Han-Ki Lee1, Yoosoo Yang1, Zengliu Su1, Changbong Hyeon, Tae-Sun Lee, Hong-Won Lee, Dae-Hyuk Kweon, Yeon-Kyun Shin, and Tae-Young Yoon / Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1/Science/201005

저서(최근 5년)

-  Methods in Molecular Biology[2018-10-14]

논문(최근 5년)

-  A Chemical Controller of SNARE-Driven Membrane Fusion That Primes Vesicles for Ca(2+)-Triggered Millisecond Exocytosis[Journal of the American Chemical Society,2016-04-01] -  Inositol pyrophosphates inhibit synaptotagmin-dependent exocytosis.[Proceedings of the National Academy of Sciences of the United States of America,2016-07-01] -  Virus-mimetic fusogenic exosomes for direct delivery of integral membrane proteins to target cell membranes[ ADVANCED MATERIALS,2017-02-06] -  Exosome-SIRPa, a CD47 blockade increases cancer cell phagocytosis[ BIOMATERIALS,2017-01-03] -  Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics[Journal of controlled release,2017-12-01] -  Cancer-derived exosomes as a delivery platform of CRISPR/Cas9 confer cancer cell tropism-dependent targeting[Journal of controlled release ,2017-11-01] -  Harnessing designed nanoparticles: Current strategies and future perspectives in cancer immunotherapy[NANO TODAY,2017-11-06] -  Nanocage-Therapeutics Prevailing Phagocytosis and Immunogenic Cell Death Awakens Immunity against Cancer[ADVANCED MATERIALS,2018-03-30] -  Exosome as a vehicle for delivery of membrane protein therapeutics, PH20, for enhanced tumor penetration and antitumor efficacy[ADVANCED FUNCTIONAL MATERIALS,2018-01-31] -  Engineering nanoparticle strategies for effective cancer immunotherapy[BIOMATERIALS,2018-09-17] -  Comparison of exosomes and ferritin protein nanocages for the delivery of membrane protein therapeutics[JOURNAL OF CONTROLLED RELEASE,2018-06-10] -  Extracellular vesicles as a platform for membrane-associated therapeutic protein delivery[JOURNAL OF EXTRACELLULAR VESICLES,2018-03-01] -  Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor-Derived Peptides for Regulation of Mast Cell Degranulation[FRONTIERS IN IMMUNOLOGY,2018-04-11] -  Combined Rho-kinase inhibition and immunogenic cell death triggers and propagates immunity against cancer[NATURE COMMUNICATIONS,2018-06-04] -  Designed trimer-mimetic TNF superfamily ligands on self-assembling nanocages[BIOMATERIALS,2018-10-01]

특허(최근 5년)

-  Rho-연관된 단백질 키나제 저해제를 포함하는 면역 반응 증강용 조성물 및 이를 이용한 방법[2018-08-21]