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bang jeong kyu

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  • 소속캠퍼스한국기초과학지원연구원
  • 전공 생물분석과학
  • 연락처043 240 5023
  • 출신전공생유기화학
  • 학위박사
  • 최종출신대학Osaka University
  • 이메일

연구분야

생유기화학

Bioorganic chemistry

대표연구실적

-  Mija Ahn, Young-Hyun Han, Jung-Eun Park, Jeong Kyu Bang/A New Class of Peptidomimetics Targeting the Polo-box domain of Polo-Like Kinase 1/Journal of Medicinal Chemistry/2014년10월27일 -  jia-Lin Jia, Young-Hyun Han, Jeong Kyu Bang, Nam-Hyung Kim, Suk namgoong/Structural basis for recognition of EMi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization/Scientific Report/2015월10월13일 -  Ganipisetti Srinivasrao, Jeong Kyu Bang/Design and Synthesis of a cell-permeable, Drug-like Small molecule inhibitor targeting the polo-box domain of polo-like kinase 1/PLoS ONE/2014년9월11일

논문(최근 5년)

-  Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1[Bioorganic and medicinal chemistry,2013-02-27] -  Non hemolytic short peptidomimetics as a new class of potent and broad-spectrum antimicrobial agents[Bioorganic and medicinal chemistry letters,2013-06-14] -  Essential role of Cenexin1 but not Odf2 in ciliogenesis[Cell cycle,2013-01-12] -  Discovery of novel histidine-derived lipo-amino acids.......[European Journal of medicinal chemistry,2013-06-26] -  Short KR-12 analogs designed from human cathelicidin LL-37 possessing both antimicrobial and antiendotoxic activities without mammalian cell toxici[Journal of Peptide Science,2013-08-14] -  Antifreeze Peptides and Glycopeptides and Their Derivatives: Potential Uses in Biotechnology[Marine Drugs,2013-06-10] -  De Novo Design and Synthesis of Ultra-Short Peptidomimetic Antibiotics Having Dual Antimicrobial and Anti-Inflammatory Activities[PLoS ONE,2013-11-26] -  Exploring the Binding Nature of Pyrrolidine Pocket- Dependent Interactions in the Polo-Box Domain of Polo- Like Kinase 1[PLoS ONE,2013-11-06] -  Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds Cep192 and Cep152[PNAS,2013-11-26] -  Poly-lysine peptidomimetics having potent antimicrobial activity without hemolytic activity[Amino Acids,2014-06-25] -  Bacterial killing mechanism of sheep myeloid antimicrobial peptide-18 (SMAP-18) and its Trp-substituted analog with improved cell selectivity and reduced mammalian cell toxicity[Amino Acids,2013-11-13] -  Enhancement of Antibacterial Activity of Short Tryptophan-rich Antimicrobial Peptide Pac-525 by Replacing Trp with His(chx)[Bull.Korean Chemical Soc.,2014-05-30] -  Mechanisms Underlying Plk1 Polo-Box Domain- Mediated Biological Processes and Their Physiological Significance[molecules and Cells,2014-01-12] -  Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis[Nature structural and molecular biology,2014-06-29] -  Enhanced cellular uptake of a TAT?conjugated peptide inhibitor targeting the polo?box domain of polo?like kinase 1[Amino Acids,2014-08-24] -  Design and Synthesis of a Cell-Permeable Drug-Like Small Molecule Inhibitor Targeting the Polo-Box Domain of Polo-Like Kinase 1[PLoS ONE,2014-09-11] -  Multi-Frequency Multi-Technique Pulsed EPR Investigation of the Copper Binding Site of Murine Amyloid b Peptide[Angew.chem.Int.Ed,2014-12-10] -  Crystal structure of Legionella pneumophila type IV secretion system effector LegAS4[Biochemical and Biophysical research Commumications,2015-08-21] -  Peptoid-Substituted Hybrid Antimicrobial Peptide Derived from Papiliocin and Magainin 2 with Enhanced Bacterial Selectivity and Anti-inflammatory Activity[Biochemistry,2015-06-08] -  Mammalian Polo-like Kinase 1 (Plk1) Promotes Proper Chromosome Segregation by Phosphorylating and Delocalizing the PBIP1 CENP-Q Complex from Kinetochores[Journal of biological Chemistry,2015-02-10] -  A New Class of Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1[Journal of Medicinal Chemistry,2014-10-27] -  Bimodal Interaction of Mammalian Polo-Like Kinase 1 and a Centrosomal Scaffold Cep192 in the Regulation of Bipolar Spindle Formation[molecular and cellular biology,2015-05-26] -  Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilizatio[Scientific Report,2015-10-13]

특허(최근 5년)

-  항균활성 및 항염증활성을 갖는 신규한 펩티드[2014-03-28]