본문 바로가기 대메뉴 바로가기
류경석 교수

Kyoung-Seok, Ryu

INFO

  • 소속캠퍼스한국기초과학지원연구원
  • 연락처043-240-5064
  • 출신전공생물과학과
  • 학위박사
  • 최종출신대학한국과학기술원
  • 이메일

연구분야

단백질 구조 및 동역학 연구

Protein structure and dynamics

대표연구실적

-  Crystal structures of the LsrR proteins complexed with phospho-AI-2 and two signal-interrupting analogs reveal distinct mechanisms for ligand recognition. JACS 2013. -  Probing the rate limiting step for intramolecular transfer of a transcription factor between specific sites on the same DNA molecule by 15Nz-exchange NMR spectroscopy. JACS 2014. -  Differential ubiquitin binding by the acidic loops of Ube2g1 and Ube2r1 distinguishes their K48-ubiquitylation activities. JBC 2015.

논문(최근 5년)

-  Structural alteration of Escherichia coli Hsp31 by thermal unfolding increases chaperone activity. [Biochim Biophys Acta,2013-02-01] -  Insights into the regulation of human Rev1 for translesion synthesis polymerases revealed by the structural studies on its polymerase-interacting domain.[J Mol Cell Biol. ,2013-02-03] -  Crystal structures of the LsrR proteins complexed with phospho-AI-2 and two signal-interrupting analogs reveal distinct mechanisms for ligand recognition. [J. Am. Chem. Soc. ,2013-09-18] -  Structural and dynamic features of cold-shock proteins of Listeria monocytogenes, a psychrophilic bacterium.[Biochemistry,2013-03-18] -  Solution structure of the RecQ C-terminal domain of human Bloom syndrome protein[J Biomol NMR,2014-01-17] -  An Unusual Protein-Protein Interaction through Coupled Unfolding and Binding[Angew Chem Int Ed Engl,2014-09-08] -  Probing the rate limiting step for intramolecular transfer of a transcription factor between specific sites on the same DNA molecule by 15Nz-exchange NMR spectroscopy[J. Am. Chem. Soc. ,2014-09-25] -  Stereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetalcontaining crystal structures[Febs J.,2014-10-04]

특허(최근 5년)

-  LsrR의 결정화 방법과 그 결정 및 LsrR 활성 조절제[2012-10-24]